2ILY

Crystal structure of poliovirus polymerase complexed with ATP and Mg2+

Summary for 2ILY

• Entry DOI: 10.2210/pdb2ily/pdb
• Related: 1RA6 1RA7 2ILZ 2IM0 2IM1 2IM2 2IM3
• Descriptor: Poliovirus polymerase, SODIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: nucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, stabilization, transferase
• Biological source: Human poliovirus 1
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300
• Total number of polymer chains: 1
• Total formula weight: 53938.39

Authors

Thompson, A.A.,Peersen, O.B. (deposition date: 2006-10-03, release date: 2006-12-12, Last modification date: 2023-08-30)

• Primary citation: Thompson, A.A.,Albertini, R.A.,Peersen, O.B.; Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.; J.Mol.Biol., 366:1459-1474, 2007; PubMed: 17223130; DOI: 10.1016/j.jmb.2006.11.070

Experimental method

X-RAY DIFFRACTION (2.6 Å)