2IM1
Crystal structure of poliovirus polymerase complexed with CTP and Mn2+
Summary for 2IM1
Entry DOI | 10.2210/pdb2im1/pdb |
Related | 1RA6 1RA7 2ILY 2ILZ 2IM0 2IM2 2IM3 |
Descriptor | poliovirus polymerase, MANGANESE (II) ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | nucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, ctp, stabilization, transferase |
Biological source | Human poliovirus 1 |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300 |
Total number of polymer chains | 1 |
Total formula weight | 53959.08 |
Authors | Thompson, A.A.,Peersen, O.B. (deposition date: 2006-10-03, release date: 2006-12-12, Last modification date: 2023-08-30) |
Primary citation | Thompson, A.A.,Albertini, R.A.,Peersen, O.B. Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions. J.Mol.Biol., 366:1459-1474, 2007 Cited by PubMed: 17223130DOI: 10.1016/j.jmb.2006.11.070 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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