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2IM1

Crystal structure of poliovirus polymerase complexed with CTP and Mn2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1Apoliovirus polymerasepolymer46152987.91UniProt (P03300)
Pfam (PF00680)
In PDB
Human poliovirus 1
2AMANGANESE (II) IONnon-polymer54.93Chemie (MN)
3ASODIUM IONnon-polymer23.01Chemie (NA)
4ACYTIDINE-5'-TRIPHOSPHATEnon-polymer483.21Chemie (CTP)
5AACETIC ACIDnon-polymer60.15Chemie (ACY)
6waterwater18.0124Chemie (HOH)
Sequence modifications
A: 1 - 461 (UniProt: P03300)
PDBExternal DatabaseDetails
Cas 96Cys 1843modified residue
Cas 212Cys 1959modified residue
Cas 281Cys 2028modified residue
Cas 290Cys 2037modified residue
Asp 446Leu 2193engineered mutation
Asp 455Arg 2202engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight52987.9
Non-Polymers*Number of molecules10
Total formula weight971.2
All*Total formula weight53959.1
*Water molecules are not included.

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PDB entries from 2024-06-12

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