1FPT

THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN THE FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS AND ITS VIRAL EPITOPE

Summary for 1FPT

• Entry DOI: 10.2210/pdb1fpt/pdb
• Descriptor: FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS, IGG2A-KAPPA C3 FAB (LIGHT CHAIN), IGG2A-KAPPA C3 FAB (HEAVY CHAIN), ... (4 entities in total)
• Functional Keywords: complex (antibody-pv-1 fragment), complex (antibody-pv-1 fragment) complex, complex (antibody/pv-1 fragment)
• Biological source: Human poliovirus 1; More
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03299; Cell membrane; Single-pass membrane protein (Potential): P01865
• Total number of polymer chains: 3
• Total formula weight: 49499.09

Authors

Wien, M.W.,Hogle, J.M. (deposition date: 1995-01-26, release date: 1995-03-31, Last modification date: 2011-07-13)

• Primary citation: Wien, M.W.,Filman, D.J.,Stura, E.A.,Guillot, S.,Delpeyroux, F.,Crainic, R.,Hogle, J.M.; Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope.; Nat.Struct.Biol., 2:232-243, 1995; PubMed: 7539711; DOI: 10.1038/nsb0395-232

Experimental method

X-RAY DIFFRACTION (3 Å)