2YO0
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2Z5H
| Crystal structure of the head-to-tail junction of tropomyosin complexed with a fragment of TnT | 分子名称: | General control protein GCN4 and Tropomyosin alpha-1 chain, Tropomyosin alpha-1 chain and General control protein GCN4, Troponin T, ... | 著者 | Murakami, K, Nozawa, K, Tomii, K, Kudou, N, Igarashi, N, Shirakihara, Y, Wakatsuki, S, Stewart, M, Yasunaga, T, Wakabayashi, T. | 登録日 | 2007-07-12 | 公開日 | 2008-04-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T Proc.Natl.Acad.Sci.USA, 105, 2008
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1YSA
| THE GCN4 BASIC REGION LEUCINE ZIPPER BINDS DNA AS A DIMER OF UNINTERRUPTED ALPHA HELICES: CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX | 分子名称: | DNA (5'-D(*AP*AP*AP*CP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*A P*GP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*A P*GP*TP*T)-3'), PROTEIN (GCN4) | 著者 | Ellenberger, T.E, Brandl, C.J, Struhl, K, Harrison, S.C. | 登録日 | 1993-08-09 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex. Cell(Cambridge,Mass.), 71, 1992
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3P8M
| Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide dimerized by leucine zipper | 分子名称: | Dynein light chain 2, General control protein GCN4 | 著者 | Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G. | 登録日 | 2010-10-14 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. Plos One, 6, 2011
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1FAV
| THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE | 分子名称: | HIV-1 ENVELOPE PROTEIN CHIMERA, PROTEIN (TRANSMEMBRANE GLYCOPROTEIN) | 著者 | Zhou, G, Ferrer, M, Chopra, R, Strassmaier, T, Weissenhorn, W, Skehel, J.J, Oprian, D, Schreiber, S.L, Harrison, S.C, Wiley, D.C. | 登録日 | 2000-07-13 | 公開日 | 2000-08-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorg.Med.Chem., 8, 2000
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1DGC
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2YO1
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6HN5
| Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | 登録日 | 2018-09-14 | 公開日 | 2018-11-21 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
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6VWG
| Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain | 著者 | Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. | 登録日 | 2020-02-19 | 公開日 | 2020-05-13 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure, 28, 2020
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7T6F
| Structure of active Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain | 分子名称: | ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Interferon lambda receptor 1, ... | 著者 | Glassman, C.R, Tsutsumi, N, Jude, K.M, Garcia, K.C. | 登録日 | 2021-12-13 | 公開日 | 2022-03-16 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation. Science, 376, 2022
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8OPO
| Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (3-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ... | 著者 | Pronker, M.F, Creutznacher, R, Hurdiss, D.L. | 登録日 | 2023-04-07 | 公開日 | 2023-08-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Sialoglycan binding triggers spike opening in a human coronavirus. Nature, 624, 2023
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6VWI
| Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain | 著者 | Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. | 登録日 | 2020-02-19 | 公開日 | 2020-05-13 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure, 28, 2020
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8OPM
| Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (closed state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ... | 著者 | Pronker, M.F, Creutznacher, R, Hurdiss, D.L. | 登録日 | 2023-04-07 | 公開日 | 2023-08-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Sialoglycan binding triggers spike opening in a human coronavirus. Nature, 624, 2023
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6HN4
| Leucine-zippered human insulin receptor ectodomain with single bound insulin - "lower" membrane-proximal part | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor,Insulin receptor,General control protein GCN4 | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | 登録日 | 2018-09-14 | 公開日 | 2018-11-21 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
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6VWJ
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6VWH
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8OPN
| Human Coronavirus HKU1 spike glycoprotein in complex with an alpha2,8-linked 9-O-acetylated disialoside (1-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ... | 著者 | Pronker, M.F, Creutznacher, R, Hurdiss, D.L. | 登録日 | 2023-04-07 | 公開日 | 2023-08-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Sialoglycan binding triggers spike opening in a human coronavirus. Nature, 624, 2023
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8EWY
| Structure of Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain | 分子名称: | ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Interferon lambda receptor 1, ... | 著者 | Caveney, N.A, Saxton, R.A, Waghray, D, Garcia, K.C. | 登録日 | 2022-10-24 | 公開日 | 2023-03-08 | 最終更新日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structural basis of Janus kinase trans-activation. Cell Rep, 42, 2023
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1LD4
| Placement of the Structural Proteins in Sindbis Virus | 分子名称: | Coat protein C, GENERAL CONTROL PROTEIN GCN4, Spike glycoprotein E1, ... | 著者 | Zhang, W, Mukhopadhyay, S, Pletnev, S.V, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2002-04-08 | 公開日 | 2002-11-04 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (11.4 Å) | 主引用文献 | Placement of the Structural Proteins in Sindbis virus J.VIROL., 76, 2002
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2G9J
| Complex of TM1a(1-14)Zip with TM9a(251-284): a model for the polymerization domain ("overlap region") of tropomyosin, Northeast Structural Genomics Target OR9 | 分子名称: | Tropomyosin 1 alpha chain, Tropomyosin 1 alpha chain/General control protein GCN4 | 著者 | Greenfield, N.J, Huang, Y.J, Swapna, G.V.T, Bhattacharya, A, Singh, A, Montelione, G.T, Hitchcock-DeGregori, S.E, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-03-06 | 公開日 | 2006-11-07 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of the Junction between Tropomyosin Molecules: Implications for Actin Binding and Regulation. J.Mol.Biol., 364, 2006
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1IHQ
| GLYTM1BZIP: A CHIMERIC PEPTIDE MODEL OF THE N-TERMINUS OF A RAT SHORT ALPHA TROPOMYOSIN WITH THE N-TERMINUS ENCODED BY EXON 1B | 分子名称: | CHIMERIC PEPTIDE GlyTM1bZip: TROPOMYOSIN ALPHA CHAIN, BRAIN-3 and GENERAL CONTROL PROTEIN GCN4 | 著者 | Greenfield, N.J, Yuang, Y.J, Palm, T, Swapna, G.V, Monleon, D, Montelione, G.T, Hitchcock-Degregori, S.E, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2001-04-19 | 公開日 | 2001-10-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure and folding dynamics of the N terminus of a rat non-muscle alpha-tropomyosin in an engineered chimeric protein. J.Mol.Biol., 312, 2001
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6UT2
| 3D structure of the leiomodin/tropomyosin binding interface | 分子名称: | Leiomodin-2, Tropomyosin alpha-1 chain chimeric peptide | 著者 | Tolkatchev, D, Smith, G.E, Helms, G.L, Cort, J.R, Kostyukova, A.S. | 登録日 | 2019-10-29 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Leiomodin creates a leaky cap at the pointed end of actin-thin filaments. Plos Biol., 18, 2020
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5IIV
| GCN4p pH 1.5 | 分子名称: | General control protein GCN4 | 著者 | Brady, M.R, Kaplan, A.R, Alexandrescu, A.T. | 登録日 | 2016-03-01 | 公開日 | 2017-03-15 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear Magnetic Resonance Structures of GCN4p Are Largely Conserved When Ion Pairs Are Disrupted at Acidic pH but Show a Relaxation of the Coiled Coil Superhelix. Biochemistry, 56, 2017
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5IEW
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5IIR
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