Complex of TM1a(1-14)Zip with TM9a(251-284): a model for the polymerization domain ("overlap region") of tropomyosin, Northeast Structural Genomics Target OR9

Summary for 2G9J

Related1TMZ 1MV4
DescriptorTropomyosin 1 alpha chain, Tropomyosin 1 alpha chain/General control protein GCN4 (2 entities in total)
Functional Keywordstropomyosin, peptide complex, overlap complex, intermolecular junction, n-terminal:c-terminal interface, parallel coiled coil, polymerization domain, structural protein, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg
Biological sourceRattus norvegicus (Norway rat)
Cellular locationNucleus P03069
Cytoplasm, cytoskeleton Q63609
Total number of polymer chains4
Total molecular weight16174.83
Primary citation
Greenfield, N.J.,Huang, Y.J.,Swapna, G.V.,Bhattacharya, A.,Rapp, B.,Singh, A.,Montelione, G.T.,Hitchcock-Degregori, S.E.
Solution NMR Structure of the Junction between Tropomyosin Molecules: Implications for Actin Binding and Regulation.
J.Mol.Biol., 364:80-96, 2006
PubMed: 16999976 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2006.08.033
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers131.2%10.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures