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PDB: 86 件
1LK2
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BU of 1lk2 by Molmil
1.35A crystal structure of H-2Kb complexed with the GNYSFYAL peptide
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Luz, J.G, Rudolph, M.G, Wilson, I.A, Eisen, H.
登録日2002-04-23
公開日2003-11-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects.
J.Immunol., 172, 2004
1G7P
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BU of 1g7p by Molmil
CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-GLUCOSIDASE P1, ...
著者Apostolopoulos, V, Yu, M, Corper, A.L, Li, W, McKenzie, I.F, Teyton, L, Wilson, I.A.
登録日2000-11-13
公開日2002-07-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.
J.Mol.Biol., 318, 2002
1KPU
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BU of 1kpu by Molmil
High resolution crystal structure of the MHC class I complex H-2Kb/VSV8
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudolph, M.G, Wilson, I.A.
登録日2002-01-02
公開日2003-06-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High Resolution Crystal Structure of H-2Kb/VSV8
To be Published
1G7Q
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BU of 1g7q by Molmil
CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND MUC1 VNTR PEPTIDE SAPDTRPA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2 MICROGLOBULIN, ...
著者Apostolopoulos, V, Yu, M, Corper, A.L, Teyton, L, Pietersz, G.A, McKenzie, I.F, Wilson, I.A.
登録日2000-11-13
公開日2002-07-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.
J.Mol.Biol., 318, 2002
3TID
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BU of 3tid by Molmil
Crystal structure of the LCMV derived peptide GP34 in complex with the murine mhc class I H-2 Kb
分子名称: ACETATE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Nguyen, T.T, Shen, Z.T, Stern, L.J.
登録日2011-08-20
公開日2012-08-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells.
J.Immunol., 191, 2013
1FZK
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BU of 1fzk by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM1 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
登録日2000-10-03
公開日2001-03-28
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
1KPV
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BU of 1kpv by Molmil
High resolution crystal structure of the MHC class I complex H-2Kb/SEV9
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class I histocompatibility antigen, ...
著者Rudolph, M.G, Wilson, I.A.
登録日2002-01-02
公開日2003-06-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献High Resolution Crystal Structure of H-2Kb/VSV8
To be Published
1LEG
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BU of 1leg by Molmil
Crystal Structure of H-2Kb bound to the dEV8 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-2-MICROGLOBULIN, ...
著者Luz, J.G, Huang, M, Garcia, K.C, Rudolph, M.G, Apostolopoulos, V, Teyton, L, Wilson, I.A.
登録日2002-04-09
公開日2002-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions.
J.Exp.Med., 195, 2002
6GB6
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BU of 6gb6 by Molmil
Structure of H-2Kb with dipeptide GL
分子名称: Beta-2-microglobulin, GLYCEROL, GLYCINE, ...
著者Hafstrand, I, Sandalova, T, Achour, A.
登録日2018-04-13
公開日2019-03-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Proc.Natl.Acad.Sci.USA, 116, 2019
1FZM
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BU of 1fzm by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
登録日2000-10-03
公開日2001-03-28
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
1FZO
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BU of 1fzo by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
登録日2000-10-03
公開日2001-03-28
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
1T0N
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BU of 1t0n by Molmil
Conformational switch in polymorphic H-2K molecules containing an HSV peptide
分子名称: Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ...
著者Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J.
登録日2004-04-12
公開日2004-11-23
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.
J Immunol., 173, 2004
2QRT
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BU of 2qrt by Molmil
Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-29
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
2ZSV
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BU of 2zsv by Molmil
Crystal structure of H-2Kb in complex with JHMV epitope S598
分子名称: 8-mer peptide from spike glycoprotein, Beta-2-microglobulin, CYSTEINE, ...
著者Theodossis, A, Dunstone, M.A, Rossjohn, J.
登録日2008-09-18
公開日2008-11-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant.
Plos Pathog., 4, 2008
1FZJ
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BU of 1fzj by Molmil
MHC CLASS I NATURAL MUTANT H-2KBM1 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudolph, M.G, Speir, J.A, Brunmark, A, Mattsson, N, Jackson, M.R, Peterson, P.A, Teyton, L, Wilson, I.A.
登録日2000-10-03
公開日2001-03-28
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.
Immunity, 14, 2001
1RJY
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BU of 1rjy by Molmil
Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B Peptide
分子名称: Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ...
著者Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H.
登録日2003-11-20
公開日2004-12-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution
J.Exp.Med., 200, 2004
2CLZ
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BU of 2clz by Molmil
Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and pBM1 peptide
分子名称: BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, ...
著者Mazza, C, Auphan-Anezin, N, Guimezanes, A, Barrett-Wilt, G.A, Montero-Julian, F, Roussel, A, Hunt, D.F, Schmitt-Verhulst, A.M, Malissen, B.
登録日2006-05-03
公開日2006-06-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distinct Orientation of the Alloreactive Monoclonal Cd8 T Cell Activation Program by Three Different Peptide/Mhc Complexes.
Eur.J.Immunol., 36, 2006
2CLV
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BU of 2clv by Molmil
MHC Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and pBM8 peptide
分子名称: BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, ...
著者Mazza, C, Auphan-Anezin, N, Guimezanes, A, Barrett-Wilt, G.A, Montero-Julian, F, Roussel, A, Hunt, D.F, Schmitt-Verhulst, A.M, Malissen, B.
登録日2006-05-02
公開日2006-06-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes.
Eur. J. Immunol., 36, 2006
5OQG
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BU of 5oqg by Molmil
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb W167A, beta-2microglobulin, and and ovalbumin-derived peptide.
分子名称: Beta-2-microglobulin,H-2 class I histocompatibility antigen, K-B alpha chain
著者Mikolajek, H, Werner, J.M.
登録日2017-08-11
公開日2018-04-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1.
J. Biol. Chem., 293, 2018
7JI2
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BU of 7ji2 by Molmil
Crystal Structure of H2-Kb in complex with a OVA mutant peptide
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Li, X, Mallis, R.J, Mizsei, R, Tan, K, Reinherz, E.L, Wang, J.
登録日2020-07-22
公開日2020-12-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection.
Science, 371, 2021
1S7S
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BU of 1s7s by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
1S7Q
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BU of 1s7q by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
3P9M
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BU of 3p9m by Molmil
Crystal Structure of H2-Kb in complex with a mutant of the chicken ovalbumin epitope OVA-G4
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Wesselingh, R, Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J.
登録日2010-10-18
公開日2011-10-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses
J.Immunol., 187, 2011
2QRI
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BU of 2qri by Molmil
Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb WT, beta-2microglobulin, and ovalbumin-derived peptide.
分子名称: H-2 class I histocompatibility antigen K-B alpha chain, Beta-2 microglobulin, ovalbumin-derived peptide
著者Mitaksov, V.E, Fremont, D.H.
登録日2007-07-28
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural engineering of pMHC reagents for T cell vaccines and diagnostics.
Chem.Biol., 14, 2007
3P9L
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BU of 3p9l by Molmil
Crystal Structure of H2-Kb in complex with the chicken ovalbumin epitope OVA
分子名称: Beta-2-microglobulin, CALCIUM ION, H-2 class I histocompatibility antigen, ...
著者Wesselingh, R, Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J.
登録日2010-10-18
公開日2011-10-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses
J.Immunol., 187, 2011

 

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