5OQG

Crystal structure of a single chain trimer composed of the MHC I heavy chain H-2Kb W167A, beta-2microglobulin, and and ovalbumin-derived peptide.

Summary for 5OQG

• Entry DOI: 10.2210/pdb5oqg/pdb
• Descriptor: Beta-2-microglobulin,H-2 class I histocompatibility antigen, K-B alpha chain (2 entities in total)
• Functional Keywords: diagnosis, epitopes, major histocompatibility complex, mice, models, molecular, molecular conformation, peptides, receptors, antigen, t-cell, t-lymphocytes, vaccines, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 96132.95

Authors

Mikolajek, H.,Werner, J.M. (deposition date: 2017-08-11, release date: 2018-04-11, Last modification date: 2024-01-17)

• Primary citation: Papakyriakou, A.,Reeves, E.,Beton, M.,Mikolajek, H.,Douglas, L.,Cooper, G.,Elliott, T.,Werner, J.M.,James, E.; The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1.; J. Biol. Chem., 293:7538-7548, 2018; PubMed: 29599287; DOI: 10.1074/jbc.RA117.000313

Experimental method

X-RAY DIFFRACTION (1.9 Å)