1G6X
 
 | | ULTRA HIGH RESOLUTION STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) MUTANT WITH ALTERED BINDING LOOP SEQUENCE | | 分子名称: | 1,2-ETHANEDIOL, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION | | 著者 | Addlagatta, A, Czapinska, H, Krzywda, S, Otlewski, J, Jaskolski, M. | | 登録日 | 2000-11-08 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (0.86 Å) | | 主引用文献 | Ultrahigh-resolution structure of a BPTI mutant.
Acta Crystallogr.,Sect.D, 57, 2001
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1K6U
 | | Crystal Structure of Cyclic Bovine Pancreatic Trypsin Inhibitor | | 分子名称: | 1,2-ETHANEDIOL, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION | | 著者 | Botos, I, Wu, Z, Lu, W, Wlodawer, A. | | 登録日 | 2001-10-17 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor.
FEBS Lett., 509, 2001
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5PTI
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1BPI
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2ZJX
 | | Bovine pancreatic trypsin inhibitor (BPTI) containing only the [5,55] disulfide bond | | 分子名称: | Pancreatic trypsin inhibitor, SULFATE ION | | 著者 | Islam, M.M, Sohya, S, Noguchi, K, Yohda, M, Kuroda, Y. | | 登録日 | 2008-03-11 | | 公開日 | 2008-10-21 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2ZVX
 | | Structure of a BPTI-[5,55] variant containing Gly/Val at the 14/38th positions | | 分子名称: | Pancreatic trypsin inhibitor, SULFATE ION | | 著者 | Islam, M.M, Sohya, S, Noguchi, K, Yohda, M, Kuroda, Y. | | 登録日 | 2008-11-24 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Thermodynamic and structural analysis of highly stabilized BPTIs by single and double mutations
Proteins, 77, 2009
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5XX2
 | | A BPTI-[5,55] variant with C14GA38L mutations | | 分子名称: | Pancreatic trypsin inhibitor, SULFATE ION | | 著者 | Islam, M.M. | | 登録日 | 2017-07-01 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Hydrophobic surface residues can stabilize a protein through improved water-protein interactions.
Febs J., 2019
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5XX3
 | | A BPTI-[5,55] variant with C14GA38G mutations | | 分子名称: | Pancreatic trypsin inhibitor, SULFATE ION | | 著者 | Islam, M.M. | | 登録日 | 2017-07-01 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Hydrophobic surface residues can stabilize a protein through improved water-protein interactions.
Febs J., 2019
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7PH1
 | | Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid | | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | | 著者 | Dimos, N, Leppkes, J, Koksch, B, Loll, B. | | 登録日 | 2021-08-16 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment.
J.Phys.Chem.B, 126, 2022
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9PTI
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4Y0Y
 | | Trypsin in complex with with BPTI | | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | | 著者 | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | | 登録日 | 2015-02-06 | | 公開日 | 2015-06-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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3P95
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4Y11
 | | Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4,4-trifluorobutanoic acid | | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | | 著者 | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | | 登録日 | 2015-02-06 | | 公開日 | 2015-06-24 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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5XX8
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3WNY
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5XX6
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1P2J
 | | Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin | | 分子名称: | CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ... | | 著者 | Helland, R, Czapinska, H, Leiros, I, Olufsen, M, Otlewski, J, Smalaas, A.O. | | 登録日 | 2003-04-15 | | 公開日 | 2004-04-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333, 2003
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4Y0Z
 | | Trypsin in complex with with BPTI mutant AMINOBUTYRIC ACID | | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | | 著者 | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | | 登録日 | 2015-02-06 | | 公開日 | 2015-06-24 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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4Y10
 | | Trypsin in complex with with BPTI mutant (2S)-2-amino-4,4-difluorobutanoic acid | | 分子名称: | CALCIUM ION, Cationic trypsin, GLYCEROL, ... | | 著者 | Loll, B, Ye, S, Berger, A.A, Muelow, U, Alings, C, Wahl, M.C, Koksch, B. | | 登録日 | 2015-02-06 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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5XX5
 | | A BPTI-[5,55] variant with C14GA38I mutations | | 分子名称: | Pancreatic trypsin inhibitor, SULFATE ION | | 著者 | Islam, M.M. | | 登録日 | 2017-07-01 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Hydrophobic surface residues can stabilize a protein through improved water-protein interactions.
Febs J., 2019
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5XX7
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4DG4
 | | Human mesotrypsin-S39Y complexed with bovine pancreatic trypsin inhibitor (BPTI) | | 分子名称: | CALCIUM ION, PRSS3 protein, Pancreatic trypsin inhibitor, ... | | 著者 | Salameh, M.A, Soares, A.S, Radisky, E.S. | | 登録日 | 2012-01-24 | | 公開日 | 2012-09-12 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.
Protein Sci., 21, 2012
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2R9P
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1QLQ
 | | Bovine Pancreatic Trypsin Inhibitor (BPTI) Mutant with Altered Binding Loop Sequence | | 分子名称: | PANCREATIC TRYPSIN INHIBITOR, SULFATE ION | | 著者 | Czapinska, H, Krzywda, S, Sheldrick, G.M, Otlewski, J, Jaskolski, M. | | 登録日 | 1999-09-10 | | 公開日 | 1999-10-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | High Resolution Structure of Bovine Pancreatic Trypsin Inhibitor with Altered Binding Loop Sequence
J.Mol.Biol., 295, 1999
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3FP7
 | | Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) cleaved at the scissile bond (LYS15-ALA16) determined to the 1.46 A resolution limit | | 分子名称: | 1,2-ETHANEDIOL, Anionic trypsin-2, CALCIUM ION, ... | | 著者 | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2009-01-04 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structure of a serine protease poised to resynthesize a peptide bond.
Proc.Natl.Acad.Sci.USA, 106, 2009
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