7PH1

Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid

Summary for 7PH1

• Entry DOI: 10.2210/pdb7ph1/pdb
• Related: 4Y0Y 4Y0Z 4Y10 4Y11
• Descriptor: Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ... (6 entities in total)
• Functional Keywords: hydrolase inhibitors, metal-binding, serine protease, hydrolase-2 inhibitor complex, hydrolase
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 2
• Total formula weight: 31786.32

Authors

Dimos, N.,Leppkes, J.,Koksch, B.,Loll, B. (deposition date: 2021-08-16, release date: 2022-03-30, Last modification date: 2024-01-31)

• Primary citation: Wehrhan, L.,Leppkes, J.,Dimos, N.,Loll, B.,Koksch, B.,Keller, B.G.; Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment.; J.Phys.Chem.B, 126:9985-9999, 2022; PubMed: 36409613; DOI: 10.1021/acs.jpcb.2c05496

Experimental method

X-RAY DIFFRACTION (1.18 Å)