7PH1
Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid
Summary for 7PH1
Entry DOI | 10.2210/pdb7ph1/pdb |
Related | 4Y0Y 4Y0Z 4Y10 4Y11 |
Descriptor | Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ... (6 entities in total) |
Functional Keywords | hydrolase inhibitors, metal-binding, serine protease, hydrolase-2 inhibitor complex, hydrolase |
Biological source | Bos taurus (cattle) More |
Total number of polymer chains | 2 |
Total formula weight | 31786.32 |
Authors | Dimos, N.,Leppkes, J.,Koksch, B.,Loll, B. (deposition date: 2021-08-16, release date: 2022-03-30, Last modification date: 2024-01-31) |
Primary citation | Wehrhan, L.,Leppkes, J.,Dimos, N.,Loll, B.,Koksch, B.,Keller, B.G. Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment. J.Phys.Chem.B, 126:9985-9999, 2022 Cited by PubMed: 36409613DOI: 10.1021/acs.jpcb.2c05496 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.18 Å) |
Structure validation
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