1K6U

Crystal Structure of Cyclic Bovine Pancreatic Trypsin Inhibitor

Summary for 1K6U

Entry DOI	10.2210/pdb1k6u/pdb
Descriptor	PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	bpti, cyclic protein, atomic resolution, hydrolase inhibitor
Cellular location	Secreted: P00974
Total number of polymer chains	1
Total formula weight	7278.06
Authors	Botos, I.,Wu, Z.,Lu, W.,Wlodawer, A. (deposition date: 2001-10-17, release date: 2001-12-19, Last modification date: 2024-10-30)
Primary citation	Botos, I.,Wu, Z.,Lu, W.,Wlodawer, A. Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor. FEBS Lett., 509:90-94, 2001 Cited by PubMed Abstract: The crystal structure of a cyclic form of a mutant of bovine pancreatic trypsin inhibitor has been solved at 1.0 A resolution. The protein was synthesized by native chemical ligation and its structure is almost indistinguishable from the previously described recombinant form of the same mutant; however, the new loop containing the former termini became much better ordered. PubMed: 11734212 DOI: 10.1016/S0014-5793(01)03113-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1 Å)

Structure validation