2ZVX

Structure of a BPTI-[5,55] variant containing Gly/Val at the 14/38th positions

Summary for 2ZVX

• Entry DOI: 10.2210/pdb2zvx/pdb
• Related: 2ZJX 3CI7
• Descriptor: Pancreatic trypsin inhibitor, SULFATE ION (3 entities in total)
• Functional Keywords: protein folding, protein stabilization, protein design, pharmaceutical, protease inhibitor, secreted, serine protease inhibitor, hydrolase inhibitor, disulfide bond
• Biological source: Bos taurus (bovine)
• Cellular location: Secreted: P00974
• Total number of polymer chains: 2
• Total formula weight: 13078.78

Authors

Islam, M.M.,Sohya, S.,Noguchi, K.,Yohda, M.,Kuroda, Y. (deposition date: 2008-11-24, release date: 2009-10-13, Last modification date: 2023-11-01)

• Primary citation: Islam, M.M.,Sohya, S.,Noguchi, K.,Kidokoro, S.,Yohda, M.,Kuroda, Y.; Thermodynamic and structural analysis of highly stabilized BPTIs by single and double mutations; Proteins, 77:962-970, 2009; PubMed: 19830687; DOI: 10.1002/prot.22522

Experimental method

X-RAY DIFFRACTION (1.09 Å)