5M3N
 
 | | HTRA2 wild-type structure | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | | 著者 | Merski, M, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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5TO1
 | | HtrA2 exposed (L266R, F303A) mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Serine protease HTRA2, ... | | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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5M3O
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5TNY
 | | HTRA2 G399S mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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5TNZ
 | | HtrA2 S142D mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, Serine protease HTRA2, ... | | 著者 | Macedo-Ribeiro, S, Merski, M, Pereira, P.J.B. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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5TO0
 | | HTRA2 S276C mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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5FHT
 | | HtrA2 protease mutant V226K | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, POTASSIUM ION, ... | | 著者 | Golik, P, Dubin, G, Zurawa-Janicka, D, Lipinska, B, Jarzab, M, Wenta, T, Gieldon, A, Ciarkowski, A. | | 登録日 | 2015-12-22 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Distinct 3D Architecture and Dynamics of the Human HtrA2(Omi) Protease and Its Mutated Variants.
Plos One, 11, 2016
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1LCY
 | | Crystal Structure of the Mitochondrial Serine Protease HtrA2 | | 分子名称: | HtrA2 serine protease | | 著者 | Li, W, Srinivasula, S.M, Chai, J, Li, P, Wu, J.W, Zhang, Z, Alnemri, E.S, Shi, Y. | | 登録日 | 2002-04-07 | | 公開日 | 2002-05-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi.
Nat.Struct.Biol., 9, 2002
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5WYN
 | | HtrA2 Pathogenic Mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Serine protease HTRA2, ... | | 著者 | Wagh, A.R, Bose, K. | | 登録日 | 2017-01-13 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis of inactivation of human counterpart of mouse motor neuron degeneration 2 mutant in serine protease HtrA2
Biosci. Rep., 38, 2018
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2PZD
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8E2K
 | | Cryo-EM structure of BIRC6/HtrA2-S306A | | 分子名称: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial | | 著者 | Hunkeler, M, Fischer, E.S. | | 登録日 | 2022-08-15 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.
Science, 379, 2023
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7VGE
 | | Structure of the PDZ deleted variant of HtrA2 protease (S306A) | | 分子名称: | Serine protease HTRA2, mitochondrial | | 著者 | Parui, A.L, Mishra, V, Bhaumik, P, Bose, K. | | 登録日 | 2021-09-15 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2.
Structure, 30, 2022
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8AUK
 | | Cryo-EM structure of human BIRC6 in complex with HTRA2. | | 分子名称: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial, ... | | 著者 | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | | 登録日 | 2022-08-25 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
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