5WYN

HtrA2 Pathogenic Mutant

Summary for 5WYN

Entry DOI	10.2210/pdb5wyn/pdb
Descriptor	Serine protease HTRA2, mitochondrial, CHLORIDE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	neurodegeneration, pathogenic mutant, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	36424.94
Authors	Wagh, A.R.,Bose, K. (deposition date: 2017-01-13, release date: 2018-08-08, Last modification date: 2023-11-22)
Primary citation	Wagh, A.R.,Bose, K. Structural basis of inactivation of human counterpart of mouse motor neuron degeneration 2 mutant in serine protease HtrA2 Biosci. Rep., 38:-, 2018 Cited by PubMed: 30068699 DOI: 10.1042/BSR20181072 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation