2PZD

Crystal Structure of the HtrA2/Omi PDZ Domain Bound to a Phage-Derived Ligand (WTMFWV)

Summary for 2PZD

• Entry DOI: 10.2210/pdb2pzd/pdb
• Related: 2JOA 2P3W
• Descriptor: Serine protease HTRA2, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: pdz domain, serine protease, apoptosis, mitochondria, peptide-binding module, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion intermembrane space: O43464
• Total number of polymer chains: 2
• Total formula weight: 25311.21

Authors

Appleton, B.A.,Wiesmann, C. (deposition date: 2007-05-17, release date: 2007-08-07, Last modification date: 2023-09-20)

• Primary citation: Zhang, Y.,Appleton, B.A.,Wu, P.,Wiesmann, C.,Sidhu, S.S.; Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain.; Protein Sci., 16:1738-1750, 2007; PubMed: 17656586; DOI: 10.1110/ps.072833207

Experimental method

X-RAY DIFFRACTION (2.75 Å)