2PZD
Crystal Structure of the HtrA2/Omi PDZ Domain Bound to a Phage-Derived Ligand (WTMFWV)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine protease HTRA2 | polymer | 113 | 12593.5 | 2 | UniProt (O43464) Pfam (PF17820) In PDB | Homo sapiens (human) | High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine proteinase OMI, Serine protease 25 |
2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
3 | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A, B: 359 - 458 (UniProt: O43464)
PDB | External Database | Details |
---|---|---|
Gly 355 | - | cloning artifact |
Ser 356 | - | cloning artifact |
His 357 | - | cloning artifact |
Met 358 | - | cloning artifact |
Gly 459 | - | linker |
Gly 460 | - | linker |
Gly 461 | - | linker |
Trp 462 | - | SEE REMARK 999 |
Thr 463 | - | SEE REMARK 999 |
Met 464 | - | SEE REMARK 999 |
Phe 465 | - | SEE REMARK 999 |
Trp 466 | - | SEE REMARK 999 |
Val 467 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 25187.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 124.1 | |
All* | Total formula weight | 25311.2 |