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PDB: 9 件

1HTJ
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STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF
分子名称: KIAA0380
著者Longenecker, K.L, Lewis, M.E, Chikumi, H, Gutkind, J.S, Derewenda, Z.S.
登録日2000-12-29
公開日2001-07-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases.
Structure, 9, 2001
5JHH
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Crystal structure of the ternary complex between the human RhoA, its inhibitor and the DH/PH domain of human ARHGEF11
分子名称: 3-{3-[ethyl(quinolin-2-yl)amino]phenyl}propanoic acid, GLYCEROL, Rho guanine nucleotide exchange factor 11, ...
著者Lv, Z, Wang, R, Ma, L, Miao, Q, Wu, J, Yan, Z, Li, J, Miao, L, Wang, F.
登録日2016-04-21
公開日2017-04-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and PDZRhoGEF
To Be Published
5TYT
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Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide
分子名称: Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera
著者Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z.
登録日2016-11-21
公開日2017-02-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.398 Å)
主引用文献Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF.
Biochem. Biophys. Res. Commun., 485, 2017
5JHG
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Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11
分子名称: GLYCEROL, Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
著者Wang, R, Chen, Q, Zhang, H, Yan, Z, Li, J, Miao, L, Wang, F.
登録日2016-04-21
公開日2017-04-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11
To Be Published
1XCG
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Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF
分子名称: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
著者Derewenda, U, Oleksy, A, Stevenson, A.S, Korczynska, J, Dauter, Z, Somlyo, A.P, Otlewski, J, Somlyo, A.V, Derewenda, Z.S.
登録日2004-09-01
公開日2004-12-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle
Structure, 12, 2004
3KZ1
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Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ...
著者Chen, Z, Sternweis, P.C, Sprang, S.R.
登録日2009-12-07
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010
3T06
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Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA
分子名称: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
著者Bielnicki, J.A, Derewenda, U, Derewenda, Z.S.
登録日2011-07-19
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF.
J.Biol.Chem., 286, 2011
5E6P
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PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
分子名称: Plexin-B2, Rho guanine nucleotide exchange factor 11
著者Pascoe, H.G, Zhang, X.
登録日2015-10-10
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.215 Å)
主引用文献Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
2DLS
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Solution structure of the PDZ domain of human Rho guanine nucleotide exchange factor 11
分子名称: Rho guanine nucleotide exchange factor 11
著者Inoue, K, Suetake, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-20
公開日2006-10-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PDZ domain of human Rho guanine nucleotide exchange factor 11
To be Published

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件を2024-11-13に公開中

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