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PDB: 420 件

6O9K
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70S initiation complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M.
登録日2019-03-14
公開日2019-05-29
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
4V55
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and ribosome recycling factor (RRF).
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-17
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
7PJW
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Structure of the 70S-EF-G-GDP-Pi ribosome complex with tRNAs in hybrid state 2 (H2-EF-G-GDP-Pi)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N.
登録日2021-08-24
公開日2021-10-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural mechanism of GTPase-powered ribosome-tRNA movement.
Nat Commun, 12, 2021
7BL6
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50S-ObgE-GMPPNP particle
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T.
登録日2021-01-18
公開日2021-05-12
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
5UYN
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70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
登録日2017-02-24
公開日2017-06-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
6WDB
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure IV-A)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6WDI
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure IV-B2)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
5KPV
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Structure of RelA bound to ribosome in presence of A/R tRNA (Structure II)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
登録日2016-07-05
公開日2016-09-28
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016
6VZJ
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Escherichia coli transcription-translation complex A1 (TTC-A1) containing mRNA with a 15 nt long spacer, fMet-tRNAs at E-site and P-site, and lacking transcription factor NusG
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
登録日2020-02-28
公開日2020-09-02
最終更新日2020-09-23
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of transcription-translation coupling.
Science, 369, 2020
7D80
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Molecular model of the cryo-EM structure of 70S ribosome in complex with peptide deformylase, trigger factor, and methionine aminopeptidase
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Akbar, S, Bhakta, S, Sengupta, J.
登録日2020-10-06
公開日2021-04-07
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the interplay of protein biogenesis factors with the 70S ribosome.
Structure, 29, 2021
7UPH
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Structure of a ribosome with tethered subunits
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Kim, D.S, Watkins, A, Bidstrup, E, Lee, J, Topkar, V.V, Kofman, C, Schwarz, K.J, Liu, Y, Pintilie, G, Roney, E, Das, R, Jewett, M.C.
登録日2022-04-15
公開日2022-08-17
最終更新日2022-08-31
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Three-dimensional structure-guided evolution of a ribosome with tethered subunits.
Nat.Chem.Biol., 18, 2022
6OST
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RF2 pre-accommodated state bound Release complex 70S at 24ms
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
登録日2019-05-02
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OGG
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BU of 6ogg by Molmil
70S termination complex with RF2 bound to the UGA codon. Rotated ribosome with RF2 bound (Structure IV).
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A.
登録日2019-04-02
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Extensive ribosome and RF2 rearrangements during translation termination.
Elife, 8, 2019
6WDC
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure IV-B)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
5GAF
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BU of 5gaf by Molmil
RNC in complex with SRP
分子名称: 1A9L SS, 23S ribosomal RNA, 50S ribosomal protein L10, ...
著者Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
登録日2015-11-25
公開日2016-02-03
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon
Nat Commun, 7, 2016
6Q98
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Structure of tmRNA SmpB bound in P site of E. coli 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rae, C.D.
登録日2018-12-17
公開日2019-02-27
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6WDH
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure IV-B1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6GXP
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Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP(RF3-only)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
登録日2018-06-27
公開日2018-08-15
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
4V5Y
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BU of 4v5y by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF).
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-19
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.45 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
8RCS
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BU of 8rcs by Molmil
Escherichia coli paused disome complex (Rotated disome interface class 1)
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Fluegel, T, Schacherl, M.
登録日2023-12-07
公開日2024-03-06
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.46 Å)
主引用文献Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8PVA
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BU of 8pva by Molmil
Structure of bacterial ribosome determined by cryoEM at 100 keV
分子名称: 16S rRNA, 23S rRNA, 50S ribosomal protein L14, ...
著者McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J.
登録日2023-07-17
公開日2023-11-29
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure determination by cryoEM at 100 keV.
Proc.Natl.Acad.Sci.USA, 120, 2023
5ADY
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BU of 5ady by Molmil
Cryo-EM structures of the 50S ribosome subunit bound with HflX
分子名称: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L10, ...
著者Zhang, Y, Mandava, C.S, Cao, W, Li, X, Zhang, D, Li, N, Zhang, Y, Zhang, X, Qin, Y, Mi, K, Lei, J, Sanyal, S, Gao, N.
登録日2015-08-25
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
5LZF
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BU of 5lzf by Molmil
Structure of the 70S ribosome with fMetSec-tRNASec in the hybrid pre-translocation state (H)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
3JCN
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BU of 3jcn by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
登録日2016-01-04
公開日2016-03-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
6XDR
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BU of 6xdr by Molmil
Escherichia coli transcription-translation complex B (TTC-B) containing an 27 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
登録日2020-06-11
公開日2020-09-02
最終更新日2020-09-23
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural basis of transcription-translation coupling.
Science, 369, 2020

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