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PDB: 22 件
5YNM
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BU of 5ynm by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppA
分子名称: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYLMETHIONINE, ZINC ION, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNF
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BU of 5ynf by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppA
分子名称: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ZINC ION, nsp10 protein, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.791 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNN
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BU of 5ynn by Molmil
Crystal structure of MERS-CoV nsp16/nsp10complex bound to sinefungin and m7GpppG
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, SINEFUNGIN, ZINC ION, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YN6
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BU of 5yn6 by Molmil
Crystal structure of MERS-CoV nsp10/nsp16 complex bound to SAM
分子名称: S-ADENOSYLMETHIONINE, ZINC ION, nsp10 protein, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.947 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNQ
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BU of 5ynq by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH and m7GpppG
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P.
登録日2017-10-25
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.958 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNO
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BU of 5yno by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH and m7GpppA
分子名称: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YN5
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BU of 5yn5 by Molmil
Crystal structure of MERS-CoV nsp10/nsp16 complex
分子名称: ZINC ION, nsp10 protein, nsp16 protein
著者Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YN8
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BU of 5yn8 by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, nsp10 protein, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNB
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BU of 5ynb by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to Sinefungin
分子名称: SINEFUNGIN, ZINC ION, nsp10 protein, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNJ
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BU of 5ynj by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppG
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ZINC ION, nsp10 protein, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.043 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
5YNI
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BU of 5yni by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, S-ADENOSYLMETHIONINE, ZINC ION, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P.
登録日2017-10-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
4RF1
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BU of 4rf1 by Molmil
Crystal structure of the Middle-East respiratory syndrome coronavirus papain-like protease in complex with ubiquitin (space group P63)
分子名称: 3-AMINOPROPANE, ORF1ab protein, S-1,2-PROPANEDIOL, ...
著者Bailey-Elkin, B.A, Johnson, G.G, Mark, B.L.
登録日2014-09-24
公開日2014-10-22
最終更新日2015-01-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression.
J.Biol.Chem., 289, 2014
5YNP
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BU of 5ynp by Molmil
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to sinefungin and m7GpppA
分子名称: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, SINEFUNGIN, ZINC ION, ...
著者Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P.
登録日2017-10-25
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex
To Be Published
6BI8
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BU of 6bi8 by Molmil
X-ray structure of MERS coronavirus papain-like protease in complex with human ISG15
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, GLYCEROL, ...
著者Clasman, J.C, Mesecar, A.D.
登録日2017-11-01
公開日2018-11-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.291 Å)
主引用文献Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease.
Antiviral Res., 174, 2020
5W8U
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BU of 5w8u by Molmil
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ...
著者Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.D, Pegan, S.D.
登録日2017-06-22
公開日2017-09-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
4P16
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BU of 4p16 by Molmil
Crystal structure of the papain-like protease of Middle-East Respiratory Syndrome coronavirus
分子名称: ORF1a, ZINC ION
著者Lei, J, Mesters, J.R, Ma, Q, Hilgenfeld, R.
登録日2014-02-25
公開日2014-05-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features.
Antiviral Res., 109C, 2014
5V69
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BU of 5v69 by Molmil
Crystal structure of the Middle East respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant ME.4
分子名称: CHLORIDE ION, ME.4, MERS-CoV PLpro, ...
著者Bailey-Elkin, B.A, Mark, B.L.
登録日2017-03-16
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
PLoS Pathog., 13, 2017
5V6A
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BU of 5v6a by Molmil
Crystal structure of the Middle East respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant ME.2
分子名称: CHLORIDE ION, CITRATE ANION, ME.2, ...
著者Bailey-Elkin, B.A, Mark, B.L.
登録日2017-03-16
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.
PLoS Pathog., 13, 2017
5W8T
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BU of 5w8t by Molmil
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ...
著者Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.V, Farhat, J.J, Pegan, S.D.
登録日2017-06-22
公開日2017-09-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
4REZ
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BU of 4rez by Molmil
Crystal structure of the Middle-East respiratory syndrome coronavirus papain-like protease
分子名称: ORF1ab protein, S-1,2-PROPANEDIOL, ZINC ION
著者Bailey-Elkin, B.A, Johnson, G.G, Mark, B.L.
登録日2014-09-24
公開日2014-10-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression.
J.Biol.Chem., 289, 2014
4RF0
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BU of 4rf0 by Molmil
Crystal structure of the Middle-East respiratory syndrome coronavirus papain-like protease in complex with ubiquitin (space group P6522)
分子名称: 3-AMINOPROPANE, ORF1ab protein, SULFATE ION, ...
著者Bailey-Elkin, B.A, Johnson, G.G, Mark, B.L.
登録日2014-09-24
公開日2014-10-22
最終更新日2015-01-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression.
J.Biol.Chem., 289, 2014
5WWP
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BU of 5wwp by Molmil
Crystal structure of Middle East respiratory syndrome coronavirus helicase (MERS-CoV nsp13)
分子名称: ORF1ab, SULFATE ION, ZINC ION
著者Hao, W, Wojdyla, J.A, Zhao, R, Han, R, Das, R, Zlatev, I, Manoharan, M, Wang, M, Cui, S.
登録日2017-01-03
公開日2017-07-05
最終更新日2021-09-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of Middle East respiratory syndrome coronavirus helicase
PLoS Pathog., 13, 2017

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件を2024-07-10に公開中

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