Summary for 4RF0
| Related | 4REZ 4RF1 |
|---|---|
| Descriptor | ORF1ab protein, Ubiquitin-60S ribosomal protein L40, ZINC ION, ... (6 entities in total) |
| Functional Keywords | zinc ribbon, deubiquitinase, papain-like protease, protein binding |
| Biological source | Human betacoronavirus 2c Jordan-N3/2012 More |
| Cellular location | Host cytoplasm, host perinuclear region . Host membrane ; Multi-pass membrane protein M4STU1 Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm P62987 |
| Total number of polymer chains | 2 |
| Total molecular weight | 45555.33 |
| Authors | Bailey-Elkin, B.A.,Johnson, G.G.,Mark, B.L. (deposition date: 2014-09-24, release date: 2014-10-22, Last modification date: 2015-01-14) |
| Primary citation | Bailey-Elkin, B.A.,Knaap, R.C.,Johnson, G.G.,Dalebout, T.J.,Ninaber, D.K.,van Kasteren, P.B.,Bredenbeek, P.J.,Snijder, E.J.,Kikkert, M.,Mark, B.L. Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression. J.Biol.Chem., 289:34667-34682, 2014 PubMed: 25320088 (PDB entries with the same primary citation) DOI: 10.1074/jbc.M114.609644  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
