5YNB

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to Sinefungin

Summary for 5YNB

• Entry DOI: 10.2210/pdb5ynb/pdb
• Descriptor: nsp16 protein, nsp10 protein, SINEFUNGIN, ... (5 entities in total)
• Functional Keywords: inhibitor, complex, transferase
• Biological source: Human betacoronavirus 2c EMC/2012; More
• Total number of polymer chains: 2
• Total formula weight: 49152.70

Authors

Wei, S.M.,Yang, L.,Ke, Z.H.,Chen, Y.,Guo, D.Y.,Fan, C.P. (deposition date: 2017-10-24, release date: 2018-12-05, Last modification date: 2023-11-22)

• Primary citation: Wei, S.M.,Yang, L.,Ke, Z.H.,Liu, Q.Y.,Chen, Y.,Yang, Z.Z.,Guo, D.Y.,Fan, C.P.; Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.98 Å)