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PDB: 146 件

6ZN5
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SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-06
公開日2020-07-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6Y0G
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BU of 6y0g by Molmil
Structure of human ribosome in classical-PRE state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-07
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
7TQL
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BU of 7tql by Molmil
CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D.
登録日2022-01-26
公開日2022-04-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
8Y0X
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BU of 8y0x by Molmil
Dormant ribosome with SERBP1
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Du, M, Zeng, F.
登録日2024-01-23
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The global structure of dormant ribosome
To Be Published
7JQC
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BU of 7jqc by Molmil
SARS-CoV-2 Nsp1, CrPV IRES and rabbit 40S ribosome complex
分子名称: 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ...
著者Yuan, S, Xiong, Y.
登録日2020-08-10
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.
Mol.Cell, 80, 2020
7WU0
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BU of 7wu0 by Molmil
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B3
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2022-02-05
公開日2022-10-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
6YBD
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BU of 6ybd by Molmil
Structure of a human 48S translational initiation complex - eIF3
分子名称: 40S ribosomal protein S13, 40S ribosomal protein S14, 40S ribosomal protein S17, ...
著者Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
登録日2020-03-16
公開日2020-09-16
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
8Y0W
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BU of 8y0w by Molmil
dormant ribosome with eIF5A, eEF2 and SERBP1
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Du, M, Zeng, F.
登録日2024-01-23
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献dormant ribosome with eIF5A, eEF2 and SERBP1
To Be Published
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
3JAH
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BU of 3jah by Molmil
Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V.
登録日2015-06-10
公開日2015-08-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
6YAN
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BU of 6yan by Molmil
Mammalian 48S late-stage translation initiation complex with histone 4 mRNA
分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
著者Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
登録日2020-03-12
公開日2020-04-08
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
6OLI
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BU of 6oli by Molmil
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
8BTK
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BU of 8btk by Molmil
Structure of the TRAP complex with the Sec translocon and a translating ribosome
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ...
著者Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N.
登録日2022-11-29
公開日2023-05-24
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis of the TRAP complex function in ER protein biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
7SYS
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BU of 7sys by Molmil
Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII).
分子名称: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-27
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
6G5I
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BU of 6g5i by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State R
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
登録日2018-03-29
公開日2018-06-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
7WTV
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BU of 7wtv by Molmil
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A2
分子名称: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2022-02-05
公開日2022-10-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
5AJ0
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BU of 5aj0 by Molmil
Cryo electron microscopy of actively translating human polysomes (POST state).
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T.
登録日2015-02-19
公開日2015-05-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Snapshots of Actively Translating Human Ribosomes
Cell(Cambridge,Mass.), 161, 2015
6Y57
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BU of 6y57 by Molmil
Structure of human ribosome in hybrid-PRE state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-25
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
7A09
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BU of 7a09 by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State III
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-08-07
公開日2020-10-14
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
8OZ0
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BU of 8oz0 by Molmil
Structure of a human 48S translation initiation complex with eIF4F and eIF4A
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V.
登録日2023-05-06
公開日2024-02-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.
Nat.Struct.Mol.Biol., 31, 2024
8XXN
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BU of 8xxn by Molmil
Cryo-EM structure of the human 43S ribosome with PDCD4
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
登録日2024-01-18
公開日2024-05-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
4UG0
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BU of 4ug0 by Molmil
STRUCTURE OF THE HUMAN 80S RIBOSOME
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ...
著者Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P.
登録日2015-03-20
公開日2015-06-10
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the human 80S ribosome
NATURE, 520, 2015
7SYR
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BU of 7syr by Molmil
Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt).
分子名称: 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-27
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
6G18
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BU of 6g18 by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State C
分子名称: 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, ...
著者Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
登録日2018-03-20
公開日2018-06-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
6G5H
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BU of 6g5h by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
登録日2018-03-29
公開日2018-06-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018

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