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PDB: 70 件

7SYV
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BU of 7syv by Molmil
Structure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure 14(wt)
分子名称: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-20
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYN
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BU of 7syn by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYP
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BU of 7syp by Molmil
Structure of the wt IRES and 40S ribosome binary complex, open conformation. Structure 10(wt)
分子名称: 18S rRNA, HCV IRES, HCV IRES partially loaded mRNA portion, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-27
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7NWH
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BU of 7nwh by Molmil
Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S.
分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ...
著者Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C.
登録日2021-03-16
公開日2021-07-07
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49, 2021
7SYK
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BU of 7syk by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYG
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BU of 7syg by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYT
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BU of 7syt by Molmil
Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt)
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYL
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BU of 7syl by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYI
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BU of 7syi by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYU
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BU of 7syu by Molmil
Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYH
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BU of 7syh by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 2(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA
To Be Published
7SYO
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BU of 7syo by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head open. Structure 9(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S2, HCV IRES, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-27
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYJ
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BU of 7syj by Molmil
Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
7SYM
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BU of 7sym by Molmil
Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII)
分子名称: 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ...
著者Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2021-11-25
公開日2022-07-13
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway
To Be Published
5K0Y
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BU of 5k0y by Molmil
m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face
分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
著者Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y.
登録日2016-05-17
公開日2016-07-13
最終更新日2018-04-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63, 2016
4KZY
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BU of 4kzy by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
分子名称: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.01 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZZ
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BU of 4kzz by Molmil
Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A
分子名称: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.0305 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZX
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BU of 4kzx by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1.
分子名称: 18S ribosomal RNA, 40S Ribosomal protein S9, 40S ribosomal protein RACK1, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.809 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4D61
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BU of 4d61 by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
著者Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
登録日2014-11-07
公開日2015-03-04
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D5L
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BU of 4d5l by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
分子名称: 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ...
著者Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
登録日2014-11-05
公開日2015-02-04
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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