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PDB: 15 件

6MI3
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BU of 6mi3 by Molmil
Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.
分子名称: NF-kB ESSENTIAL MODULATOR,NF-kappa-B essential modulator,NF-kB ESSENTIAL MODULATOR
著者Pellegrini, M, Barczewski, A.H, Mierke, D.F, Ragusa, M.J.
登録日2018-09-19
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.783 Å)
主引用文献The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface.
Sci Rep, 9, 2019
7T2U
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BU of 7t2u by Molmil
SARS-CoV2 3C-Like protease complexed with Nemo peptide
分子名称: 3C-Like Protease, NEMO peptide
著者Wakatsuki, S, Mathews, I.I, Hameedi, M.A.
登録日2021-12-06
公開日2022-09-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro.
Nat Commun, 13, 2022
3BRV
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BU of 3brv by Molmil
NEMO/IKKb association domain structure
分子名称: Inhibitor of nuclear factor kappa-B kinase subunit beta, NF-kappa-B essential modulator
著者Silvian, L.F.
登録日2007-12-21
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site.
Structure, 16, 2008
3BRT
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BU of 3brt by Molmil
NEMO/IKK association domain structure
分子名称: Inhibitor of nuclear factor kappa-B kinase subunit beta,Inhibitor of nuclear factor kappa-B kinase subunit alpha, NF-kappa-B essential modulator
著者Silvian, L.F.
登録日2007-12-21
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site.
Structure, 16, 2008
4BWN
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BU of 4bwn by Molmil
NEMO CC2-LZ DOMAIN
分子名称: NF-KAPPA-B ESSENTIAL MODULATOR
著者Dubosclard, V, Duquerroy, S, Fontan, E, Agou, F.
登録日2013-07-03
公開日2014-07-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献High-Resolution of Crystal Structure of the Human Cc2-Lz Domain of Nemo by Protein Engineering
To be Published
6MI4
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BU of 6mi4 by Molmil
Structure of the I65M mutant of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.
分子名称: NF-kB ESSENTIAL MODULATOR
著者Pellegrini, M, Barczewski, A.H, Mierke, D.F, Ragusa, M.J.
登録日2018-09-19
公開日2019-08-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.50009418 Å)
主引用文献The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface.
Sci Rep, 9, 2019
6XX0
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BU of 6xx0 by Molmil
Crystal structure of NEMO in complex with Ubv-LIN
分子名称: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b, ...
著者Akutsu, M, Skenderovic, A, Garcia-Pardo, J, Maculins, T, Dikic, I.
登録日2020-01-26
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Cell Chem Biol, 27, 2020
3CL3
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BU of 3cl3 by Molmil
Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome
分子名称: NF-kappa-B essential modulator, ORF K13
著者Bagneris, C, Ageichik, A.V, Cronin, N, Boshoff, C, Waksman, G, Barrett, T.
登録日2008-03-18
公開日2008-06-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome.
Mol.Cell, 30, 2008
6YEK
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BU of 6yek by Molmil
Crystal structure of human NEMO apo form
分子名称: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b
著者Garcia-Pardo, J, Akutsu, M, Busse, P, Skenderovic, A, Maculins, T, Dikic, I.
登録日2020-03-25
公開日2021-03-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Cell Chem Biol, 27, 2020
3FX0
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BU of 3fx0 by Molmil
Crystal structure of Human NEMO CC2_LZ domain
分子名称: NF-kappa-B essential modulator
著者Lo, Y.C, Lin, S.C, Wu, H.
登録日2009-01-19
公開日2009-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for recognition of diubiquitins by NEMO.
Mol.Cell, 33, 2009
5LDE
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BU of 5lde by Molmil
Crystal structure of a vFLIP-IKKgamma stapled peptide dimer
分子名称: Immunoglobulin G-binding protein G,Viral FLICE protein, Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, ...
著者Barrett, T.
登録日2016-06-24
公開日2017-10-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献IKK gamma-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection.
J. Virol., 91, 2017
7TV4
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BU of 7tv4 by Molmil
Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin
分子名称: E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, Polyubiquitin-C, ...
著者Rahighi, S, Iyer, M, Oveisi, H.
登録日2022-02-03
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain.
Sci Rep, 12, 2022
2JVX
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BU of 2jvx by Molmil
Solution Structure of human NEMO zinc finger
分子名称: NF-kappa-B essential modulator, ZINC ION
著者Cordier, F, Vinolo, E, Veron, M, Delepierre, M, Agou, F.
登録日2007-09-28
公開日2008-03-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.
J.Mol.Biol., 377, 2008
5AAY
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BU of 5aay by Molmil
TBK1 recruitment to cytosol-invading Salmonella induces anti- bacterial autophagy
分子名称: NF-KAPPA-B ESSENTIAL MODULATOR, ZINC ION
著者Thurston, T.l, Allen, M.D, Ravenhill, B, Karpiyevitch, M, Bloor, S, Kaul, A, Matthews, S, Komander, D, Holden, D, Bycroft, M, Randow, F.
登録日2015-07-31
公開日2016-07-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Recruitment of Tbk1 to Cytosol-Invading Salmonella Induces Wipi2-Dependent Antibacterial Autophagy.
Embo J., 35, 2016
2JVY
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BU of 2jvy by Molmil
Solution Structure of the EDA-ID-related C417F mutant of human NEMO zinc finger
分子名称: NF-kappa-B essential modulator, ZINC ION
著者Cordier, F, Vinolo, E, Veron, M, Delepierre, M, Agou, F.
登録日2007-09-28
公開日2008-03-18
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation.
J.Mol.Biol., 377, 2008

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件を2024-07-10に公開中

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