6XX0
Crystal structure of NEMO in complex with Ubv-LIN
Summary for 6XX0
| Entry DOI | 10.2210/pdb6xx0/pdb |
| Descriptor | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b, Ubv-LIN (3 entities in total) |
| Functional Keywords | inhibitor, ubiquitin, protein binding |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 38561.92 |
| Authors | Akutsu, M.,Skenderovic, A.,Garcia-Pardo, J.,Maculins, T.,Dikic, I. (deposition date: 2020-01-26, release date: 2021-02-03, Last modification date: 2024-01-24) |
| Primary citation | Maculins, T.,Garcia-Pardo, J.,Skenderovic, A.,Gebel, J.,Putyrski, M.,Vorobyov, A.,Busse, P.,Varga, G.,Kuzikov, M.,Zaliani, A.,Rahighi, S.,Schaeffer, V.,Parnham, M.J.,Sidhu, S.S.,Ernst, A.,Dotsch, V.,Akutsu, M.,Dikic, I. Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol, 27:1441-1451.e7, 2020 Cited by PubMed: 32726587DOI: 10.1016/j.chembiol.2020.07.010 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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