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PDB: 260 件

7TZC
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A drug and ATP binding site in type 1 ryanodine receptor
分子名称: (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R.
登録日2022-02-15
公開日2022-05-18
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献A drug and ATP binding site in type 1 ryanodine receptor.
Structure, 30, 2022
8AHS
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Crystal structure of human Ca2+/Calmodulin in complex with melittin
分子名称: CALCIUM ION, Calmodulin-1, Melittin
著者Durvanger, Z, Harmat, V.
登録日2022-07-22
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structures of calmodulin-melittin complexes show multiple binding modes lacking classical anchoring interactions.
J.Biol.Chem., 299, 2023
3HR4
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Human iNOS Reductase and Calmodulin Complex
分子名称: CALCIUM ION, Calmodulin, FLAVIN MONONUCLEOTIDE, ...
著者Xia, C, Misra, I, Iyanaki, T, Kim, J.J.K.
登録日2009-06-08
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase
J.Biol.Chem., 2009
1YRU
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Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin and 1mM calcium chloride
分子名称: Bifunctional hemolysin-adenylate cyclase, CALCIUM ION, Calmodulin
著者Guo, Q, Shen, Y, Tang, W.J.
登録日2005-02-04
公開日2005-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin
Embo J., 24, 2005
6DAH
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2.5 Angstrom crystal structure of the N97S CaM mutant
分子名称: CALCIUM ION, Calmodulin-1
著者Wang, K, Van Petegem, F.
登録日2018-05-01
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3OXQ
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BU of 3oxq by Molmil
Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L.
登録日2010-09-21
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization.
Embo J., 29, 2010
8FO6
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Nucleotide-free structure of a functional construct of eukaryotic elongation factor 2 kinase.
分子名称: CALCIUM ION, Calmodulin-1, Eukaryotic elongation factor 2 kinase, ...
著者Piserchio, A, Isiorho, E.A, Dalby, K.N, Ghose, R.
登録日2022-12-29
公開日2023-05-03
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin.
Proc.Natl.Acad.Sci.USA, 120, 2023
8B6Q
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X-ray structure of the haloalkane dehalogenase HaloTag7 with an insertion of Calmodulin-M13 fusion at position 154-156 that mimic the structure of CaProLa, an calcium gated protein labeling technology
分子名称: CALCIUM ION, CHLORIDE ION, Haloalkane dehalogenase,Calmodulin-1,Haloalkane dehalogenase,Calmodulin-1,M13 peptide
著者Tarnawski, M, Johnsson, K, Hiblot, J.
登録日2022-09-27
公開日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献X-ray structure of the haloalkane dehalogenase HaloTag7 with an insertion of Calmodulin-M13 fusion at position 154-156 that mimic the structure of CaProLa, an calcium gated protein labeling technology
To Be Published
3EWV
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BU of 3ewv by Molmil
Crystal Structure of calmodulin complexed with a peptide
分子名称: CALCIUM ION, Calmodulin, Tumor necrosis factor receptor superfamily member 16
著者Jiang, T, Cao, P, Gong, Y, Yu, H.J, Gui, W.J, Zhang, W.T.
登録日2008-10-16
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into the mechanism of calmodulin binding to death receptors.
Acta Crystallogr.,Sect.D, 70, 2014
6B8Q
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Crystal Structure of the Mg2+/CaM:Kv7.5 (KCNQ5) AB domain complex
分子名称: Calmodulin-1, MAGNESIUM ION, Potassium voltage-gated channel subfamily KQT member 5
著者Chang, A, Abderemane-Ali, F, Minor, D.L.
登録日2017-10-09
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Calmodulin C-Lobe Ca
Neuron, 97, 2018
3DVM
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BU of 3dvm by Molmil
Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
4GOW
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Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex
分子名称: CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 4
著者Xu, Q, Chang, A, Tolia, A, Minor Jr, D.L.
登録日2012-08-20
公開日2012-12-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation.
J.Mol.Biol., 425, 2013
3O78
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The structure of Ca2+ Sensor (Case-12)
分子名称: CALCIUM ION, Myosin light chain kinase, smooth muscle,Green fluorescent protein,Green fluorescent protein,Calmodulin-1
著者Leder, L, Stark, W, Freuler, F, Marsh, M, Meyerhofer, M, Stettler, T, Mayr, L.M, Britanova, O.V, Strukova, L.A, Chudakov, D.M.
登録日2010-07-30
公開日2010-09-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of Ca2+ sensor Case16 reveals the mechanism of reaction to low Ca2+ concentrations
Sensors (Basel), 10, 2010
3EVV
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Crystal Structure of Calcium bound dimeric GCAMP2 (#2)
分子名称: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
著者Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H.
登録日2008-10-13
公開日2008-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
7ZRP
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BU of 7zrp by Molmil
2.65 Angstrom crystal structure of Ca/CaM:CaMKIIdelta peptide complex
分子名称: CALCIUM ION, Calcium/calmodulin-dependent protein kinase type II subunit delta, Calmodulin-1, ...
著者Helassa, N, Antonyuk, S.
登録日2022-05-04
公開日2022-12-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Calmodulin variant E140G associated with long QT syndrome impairs CaMKII delta autophosphorylation and L-type calcium channel inactivation.
J.Biol.Chem., 299, 2022
5COC
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BU of 5coc by Molmil
Fusion protein of human calmodulin and B4 domain of protein A from staphylococcal aureus
分子名称: CALCIUM ION, Immunoglobulin G-binding protein A,Calmodulin
著者Jeong, W.H, Lee, H, Song, D.H, Lee, J.O.
登録日2015-07-20
公開日2016-03-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6691 Å)
主引用文献Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker.
Nat Commun, 7, 2016
7VUO
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BU of 7vuo by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
分子名称: CALCIUM ION, Calmodulin-1, Kv7.1
著者Chen, L.
登録日2021-11-03
公開日2022-11-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.679 Å)
主引用文献Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
7U9T
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Structure of PKA phosphorylated human RyR2 in the closed state in the presence of Calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2022-03-11
公開日2022-08-03
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
6MUD
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BU of 6mud by Molmil
Voltage-gated sodium channel NaV1.5 C-terminal domain in complex with Ca2+/Calmodulin
分子名称: CALCIUM ION, Calmodulin-1, Sodium channel protein type 5 subunit alpha
著者Gardill, B.R, Tung, C.C, Van Petegem, F.
登録日2018-10-23
公開日2019-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Crystal structures of Ca2+-calmodulin bound to NaVC-terminal regions suggest role for EF-hand domain in binding and inactivation.
Proc.Natl.Acad.Sci.USA, 116, 2019
8J05
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BU of 8j05 by Molmil
Human KCNQ2-CaM complex in the presence of PIP2
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2
著者Ma, D, Li, X, Guo, J.
登録日2023-04-09
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J03
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Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state I
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, cannabidiol
著者Ma, D, Li, D, Guo, J.
登録日2023-04-09
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8J04
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Human KCNQ2-CaM-HN37 complex in the presence of PIP2
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate
著者Ma, D, Li, X, Guo, J.
登録日2023-04-09
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8XYA
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BU of 8xya by Molmil
hPhK alpha-beta-gamma-delta subcomplex in inactive state
分子名称: Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者Yang, X.K, Xiao, J.Y.
登録日2024-01-19
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Architecture and activation of human muscle phosphorylase kinase.
Nat Commun, 15, 2024
6K4K
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Crystal structure of SidJ-CaM binary complex at 2.71 A
分子名称: CALCIUM ION, Calmodulin-1, SidJ
著者Ouyang, S.Y.
登録日2019-05-24
公開日2019-07-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.715 Å)
主引用文献Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase.
Nature, 572, 2019
4BYF
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Crystal structure of human Myosin 1c in complex with calmodulin in the pre-power stroke state
分子名称: ADP ORTHOVANADATE, CALMODULIN, MAGNESIUM ION, ...
著者Munnich, S, Taft, M.H, Pathan-Chhatbar, S, Manstein, D.J.
登録日2013-07-19
公開日2014-03-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Crystal Structure of Human Myosin 1C-the Motor in Glut4 Exocytosis: Implications for Ca(2+) Regulation and 14-3-3 Binding.
J.Mol.Biol., 426, 2014

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件を2024-07-10に公開中

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