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PDB: 280 件

6VYP
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Crystal structure of the LSD1/CoREST histone demethylase bound to its nucleosome substrate
分子名称: DNA (191-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A type 1, ...
著者Kim, S, Zhu, J, Eek, P, Yennawar, N, Song, T.
登録日2020-02-27
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.99 Å)
主引用文献Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Mol.Cell, 78, 2020
8GXQ
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BU of 8gxq by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y.
登録日2022-09-21
公開日2022-11-02
実験手法ELECTRON MICROSCOPY (5.04 Å)
主引用文献Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
6ESH
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BU of 6esh by Molmil
Nucleosome breathing : Class 3
分子名称: DNA (137-MER), Histone H2A, Histone H2B 1.1, ...
著者Bilokapic, S, Halic, M.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
7X3T
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BU of 7x3t by Molmil
Cryo-EM structure of ISW1a-dinucleosome
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (343-MER), ...
著者Lifei, L, Kangjing, C, Chen, Z.
登録日2022-03-01
公開日2023-09-20
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Structure of the ISW1a complex bound to the dinucleosome.
Nat.Struct.Mol.Biol., 31, 2024
5NL0
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BU of 5nl0 by Molmil
Crystal structure of a 197-bp palindromic 601L nucleosome in complex with linker histone H1
分子名称: DNA (197-MER), Histone H1.0-B, Histone H2A type 1, ...
著者Garcia-Saez, I, Petosa, C, Dimitrov, S.
登録日2017-04-03
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (5.4 Å)
主引用文献Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.
Mol. Cell, 66, 2017
6ESG
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BU of 6esg by Molmil
Nucleosome breathing : Class 2
分子名称: DNA (141-MER), Histone H2A, Histone H2B 1.1, ...
著者Bilokapic, S, Halic, M.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
5OY7
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BU of 5oy7 by Molmil
Structure of the 4_601_157 tetranucleosome (P1 form)
分子名称: CHLORIDE ION, DNA (619-MER), Histone H2A, ...
著者Ekundayo, B, Richmond, T.J, Schalch, T.
登録日2017-09-07
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (5.774 Å)
主引用文献Capturing Structural Heterogeneity in Chromatin Fibers.
J. Mol. Biol., 429, 2017
6W5N
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BU of 6w5n by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05)
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
6PWV
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BU of 6pwv by Molmil
Cryo-EM structure of MLL1 core complex bound to the nucleosome
分子名称: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
登録日2019-07-23
公開日2019-12-18
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
6ESI
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BU of 6esi by Molmil
Nucleosome breathing : Class 4
分子名称: DNA (133-MER), Histone H2A, Histone H2B 1.1, ...
著者Bilokapic, S, Halic, M.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
7ZSB
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BU of 7zsb by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Wang, H, Cramer, P.
登録日2022-05-06
公開日2022-11-16
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8ETT
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BU of 8ett by Molmil
Class1 of the INO80-Hexasome complex
分子名称: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
登録日2022-10-17
公開日2023-07-12
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (6.68 Å)
主引用文献Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
5OXV
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BU of 5oxv by Molmil
Structure of the 4_601_157 tetranucleosome (C2 form)
分子名称: DNA STRAND 1 (601-based sequence model), DNA STRAND 2 (601-based sequence model), Histone H2A, ...
著者Ekundayo, B, Schalch, T.
登録日2017-09-07
公開日2017-10-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (6.721 Å)
主引用文献Capturing Structural Heterogeneity in Chromatin Fibers.
J. Mol. Biol., 429, 2017
6JMA
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BU of 6jma by Molmil
cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome
分子名称: DNA I&J, Histone H2A, Histone H2B 1.1, ...
著者Jang, S, Song, J.J.
登録日2019-03-07
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
7EGP
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BU of 7egp by Molmil
The structure of SWI/SNF-nucleosome complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ...
著者Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P.
登録日2021-03-24
公開日2022-01-12
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity.
Cell Discov, 7, 2021
6W5I
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BU of 6w5i by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01)
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U.
登録日2020-03-13
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
Nat Commun, 12, 2021
6KW3
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BU of 6kw3 by Molmil
The ClassA RSC-Nucleosome Complex
分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
著者Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
登録日2019-09-05
公開日2019-11-13
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (7.13 Å)
主引用文献Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
6JM9
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BU of 6jm9 by Molmil
cryo-EM structure of DOT1L bound to unmodified nucleosome
分子名称: DNA strand I, DNA strand J, Histone H2A, ...
著者Jang, S, Song, J.J.
登録日2019-03-07
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
6KW4
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BU of 6kw4 by Molmil
The ClassB RSC-Nucleosome Complex
分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ...
著者Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
登録日2019-09-06
公開日2019-11-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (7.55 Å)
主引用文献Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
8JHO
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BU of 8jho by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with di-nucleosome
分子名称: Chromatin modification-related protein EAF3, Di-nucleosome template foward, Di-nucleosome template reverse, ...
著者Wang, H.
登録日2023-05-25
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7VVZ
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BU of 7vvz by Molmil
NuA4 bound to the nucleosome
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
著者Qu, K, Chen, Z.
登録日2021-11-09
公開日2022-08-10
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022
6UXW
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BU of 6uxw by Molmil
SWI/SNF nucleosome complex with ADP-BeFx
分子名称: 601 sequence bottom strand, 601 sequence top strand, ADENOSINE-5'-DIPHOSPHATE, ...
著者He, Y, Han, Y.
登録日2019-11-08
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (8.96 Å)
主引用文献Cryo-EM structure of SWI/SNF complex bound to a nucleosome.
Nature, 579, 2020
1ZBB
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BU of 1zbb by Molmil
Structure of the 4_601_167 Tetranucleosome
分子名称: DNA STRAND 1 (ARBITRARY MODEL SEQUENCE), DNA STRAND 2 (ARBITRARY MODEL SEQUENCE), HISTONE H3, ...
著者Schalch, T, Duda, S, Sargent, D.F, Richmond, T.J.
登録日2005-04-08
公開日2005-07-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (9 Å)
主引用文献X-ray structure of a tetranucleosome and its implications for the chromatin fibre.
Nature, 436, 2005
6X0N
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Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
分子名称: DNA (167-MER), Histone H2A, Histone H2B 1.1, ...
著者Halic, M, Bilokapic, S.
登録日2020-05-16
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
6G0L
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BU of 6g0l by Molmil
Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
著者Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A.
登録日2018-03-19
公開日2018-08-22
最終更新日2018-11-21
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome.
Elife, 7, 2018

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