8UQP
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![BU of 8uqp by Molmil](/molmil-images/mine/8uqp) | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-24 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome Nat.Struct.Mol.Biol., 2024
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8FIZ
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![BU of 8fiz by Molmil](/molmil-images/mine/8fiz) | Cryo-EM structure of E. coli 70S Ribosome containing mRNA and tRNA (in the transcription-translation complex) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | 登録日 | 2022-12-18 | 公開日 | 2023-03-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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7JSW
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![BU of 7jsw by Molmil](/molmil-images/mine/7jsw) | |
6VYR
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![BU of 6vyr by Molmil](/molmil-images/mine/6vyr) | Escherichia coli transcription-translation complex A1 (TTC-A1) containing an 18 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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5UYQ
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![BU of 5uyq by Molmil](/molmil-images/mine/5uyq) | 70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
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4V6D
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![BU of 4v6d by Molmil](/molmil-images/mine/4v6d) | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | 登録日 | 2009-06-27 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.814 Å) | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting. Science, 325, 2009
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7AFN
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![BU of 7afn by Molmil](/molmil-images/mine/7afn) | Bacterial 30S ribosomal subunit assembly complex state B (head domain) | 分子名称: | 16SrRNA (head domain of the 30S ribosome), 30S ribosomal protein S10, 30S ribosomal protein S13, ... | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | 登録日 | 2020-09-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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5KCS
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![BU of 5kcs by Molmil](/molmil-images/mine/5kcs) | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Evernimycin, mRNA, TetM and P-site tRNA at 3.9A resolution | 分子名称: | (2R,3R,4R,6S)-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7S,7aR)-6-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4S,5S,6S)-6-({(2R,3aS,3a'R,6S,7R,7'R,7aS,7a'S)-7'-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-7-hydroxyoctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4',7-dihydroxy-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-4-{[(2R,4S,5R,6S)-5-methoxy-4,6-dimethyl-4-nitrotetrahydro-2H-pyran-2-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N. | 登録日 | 2016-06-06 | 公開日 | 2016-08-17 | 最終更新日 | 2019-12-25 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome. Proc.Natl.Acad.Sci.USA, 113, 2016
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5KPX
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![BU of 5kpx by Molmil](/molmil-images/mine/5kpx) | Structure of RelA bound to ribosome in presence of A/R tRNA (Structure IV) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-07-05 | 公開日 | 2016-09-28 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Ribosome•RelA structures reveal the mechanism of stringent response activation. Elife, 5, 2016
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5KPS
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![BU of 5kps by Molmil](/molmil-images/mine/5kps) | Structure of RelA bound to ribosome in absence of A/R tRNA (Structure I) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-07-05 | 公開日 | 2016-09-28 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Ribosome•RelA structures reveal the mechanism of stringent response activation. Elife, 5, 2016
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5UYP
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![BU of 5uyp by Molmil](/molmil-images/mine/5uyp) | 70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
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6O9J
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![BU of 6o9j by Molmil](/molmil-images/mine/6o9j) | 70S Elongation Competent Ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Frank, J, Gonzalez Jr, R.L, Kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | 登録日 | 2019-03-14 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature, 570, 2019
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6GXN
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![BU of 6gxn by Molmil](/molmil-images/mine/6gxn) | Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State III) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N. | 登録日 | 2018-06-27 | 公開日 | 2018-08-15 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nat Commun, 9, 2018
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6WD7
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![BU of 6wd7 by Molmil](/molmil-images/mine/6wd7) | Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure II-D) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Korostelev, A.A. | 登録日 | 2020-03-31 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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6OT3
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![BU of 6ot3 by Molmil](/molmil-images/mine/6ot3) | RF2 accommodated state bound Release complex 70S at 24 ms | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | 登録日 | 2019-05-02 | 公開日 | 2019-06-19 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OGF
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![BU of 6ogf by Molmil](/molmil-images/mine/6ogf) | 70S termination complex with RF2 bound to the UGA codon. Partially rotated ribosome with RF2 bound (Structure III). | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | 登録日 | 2019-04-02 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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7SS9
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![BU of 7ss9 by Molmil](/molmil-images/mine/7ss9) | Late translocation intermediate with EF-G partially dissociated (Structure V) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Carbone, C.E, Loveland, A.B, Gamper, H.B, Hou, Y, Korostelev, A.A. | 登録日 | 2021-11-10 | 公開日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
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6ZTN
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![BU of 6ztn by Molmil](/molmil-images/mine/6ztn) | E. coli 70S-RNAP expressome complex in NusG-coupled state (42 nt intervening mRNA) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | 登録日 | 2020-07-20 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
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8VS9
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![BU of 8vs9 by Molmil](/molmil-images/mine/8vs9) | Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site and deacyl-tRNA in the E site of E. coli 70S ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Teran, D, Zhang, Y, Korostelev, A.A. | 登録日 | 2024-01-23 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon. Front Microbiol, 15, 2024
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5KPW
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![BU of 5kpw by Molmil](/molmil-images/mine/5kpw) | Structure of RelA bound to ribosome in presence of A/R tRNA (Structure III) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-07-05 | 公開日 | 2016-09-28 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Ribosome•RelA structures reveal the mechanism of stringent response activation. Elife, 5, 2016
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5UYK
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![BU of 5uyk by Molmil](/molmil-images/mine/5uyk) | 70S ribosome bound with cognate ternary complex not base-paired to A site codon (Structure I) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
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6GXO
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![BU of 6gxo by Molmil](/molmil-images/mine/6gxo) | Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and P/E-tRNA (State IV) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N. | 登録日 | 2018-06-27 | 公開日 | 2018-08-15 | 最終更新日 | 2018-10-24 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nat Commun, 9, 2018
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3J9Y
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![BU of 3j9y by Molmil](/molmil-images/mine/3j9y) | Cryo-EM structure of tetracycline resistance protein TetM bound to a translating E.coli ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Arenz, S, Nguyen, F, Beckmann, R, Wilson, D.N. | 登録日 | 2015-03-23 | 公開日 | 2015-04-15 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9- angstrom resolution. Proc.Natl.Acad.Sci.USA, 112, 2015
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4V56
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![BU of 4v56 by Molmil](/molmil-images/mine/4v56) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. | 登録日 | 2007-07-21 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.93 Å) | 主引用文献 | A steric block in translation caused by the antibiotic spectinomycin. Acs Chem.Biol., 2, 2007
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6BY1
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![BU of 6by1 by Molmil](/molmil-images/mine/6by1) | E. coli pH03H9 complex | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Amiri, H, Noller, H.F. | 登録日 | 2017-12-19 | 公開日 | 2019-02-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | 主引用文献 | Structural evidence for product stabilization by the ribosomal mRNA helicase. Rna, 25, 2019
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