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PDB: 465 件

5VA6
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CRYSTAL STRUCTURE OF ATXR5 IN COMPLEX WITH HISTONE H3.1 MONO-METHYLATED ON R26
分子名称: Histone H3.1, Probable Histone-lysine N-methyltransferase ATXR5, S-ADENOSYL-L-HOMOCYSTEINE
著者Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.-F.
登録日2017-03-24
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for the methylation specificity of ATXR5 for histone H3.
Nucleic Acids Res., 45, 2017
5V22
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Crystal structure of human SETD2 SET-domain in complex with H3K36M peptide and SAH
分子名称: Histone H3K36M peptide, Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Zhang, Y, Tong, L.
登録日2017-03-02
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.
Sci Rep, 7, 2017
3AZG
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Crystal Structure of Human Nucleosome Core Particle Containing H3K115Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
5AVB
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human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
8GE0
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Crystal structure of JADE1 PZP domain in complex with Histone H3
分子名称: Histone H3.1,Protein Jade-1, ZINC ION
著者Klein, B.J, Liu, J, Kutateladze, T.G.
登録日2023-03-06
公開日2024-03-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 2024
5XFQ
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Ternary complex of PHF1, a DNA duplex and a histone peptide
分子名称: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, Peptide from Histone H3, ...
著者Wang, Z, Li, H.
登録日2017-04-11
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017
5VNB
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YEATS in complex with histone H3
分子名称: 1,2-ETHANEDIOL, H3K23acK27ac peptide, SULFATE ION, ...
著者Cho, H.J, Cierpicki, T.
登録日2017-04-29
公開日2018-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.
ACS Chem. Biol., 13, 2018
3UIG
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crystal structure of human Survivin in complex with T3 phosphorylated H3(1-15) peptide
分子名称: Baculoviral IAP repeat-containing protein 5, T3 phosphorylated H3(1-15) peptide, ZINC ION
著者Du, J, Patel, D.J.
登録日2011-11-04
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
5T8R
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Crystal structure of human BAZ2A PHD zinc finger in complex with unmodified H3 10-mer
分子名称: Bromodomain adjacent to zinc finger domain protein 2A, GLYCEROL, Histone H3.1, ...
著者Amato, A, Gadd, M.S, Bortoluzzi, A, Ciulli, A.
登録日2016-09-08
公開日2017-04-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains.
Biochem. J., 474, 2017
2B2W
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Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
5AV5
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human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-11
公開日2015-12-23
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
6JR1
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Crystal structure of the human nucleosome phased with 16 selenium atoms
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W.
登録日2019-04-02
公開日2019-10-02
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure determination of the nucleosome core particle by selenium SAD phasing.
Acta Crystallogr D Struct Biol, 75, 2019
3U3D
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BU of 3u3d by Molmil
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine
分子名称: GLYCEROL, Transcriptional regulatory protein sir2 homologue, ZINC ION, ...
著者Zhou, Y, Hao, Q.
登録日2011-10-05
公開日2011-11-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine
Acs Chem.Biol., 2011
5AVC
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human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
2V83
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
4QBQ
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BU of 4qbq by Molmil
Crystal structure of DNMT3a ADD domain bound to H3 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
著者Li, H, Patel, D.J.
登録日2014-05-08
公開日2015-05-13
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
5Y20
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Crystal structure of AL1 PHD finger bound to H3K4me3
分子名称: PEPTIDE FROM HISTONE H3, PHD finger protein ALFIN-LIKE 1, ZINC ION
著者Zhao, S, Zhang, B, Li, H.
登録日2017-07-22
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.409 Å)
主引用文献Systematic Profiling of Histone Readers in Arabidopsis thaliana.
Cell Rep, 22, 2018
5V21
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Crystal structure of human SETD2 SET-domain in complex with H3K36M peptide and SAM
分子名称: Histone H3K36M peptide, Histone-lysine N-methyltransferase SETD2, S-ADENOSYLMETHIONINE, ...
著者Zhang, Y, Tong, L.
登録日2017-03-02
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.415 Å)
主引用文献Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.
Sci Rep, 7, 2017
7X8F
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Crystal structure of ENL T4 mutant YEATS domain in complex with histone H3 acetylation at K27
分子名称: CHLORIDE ION, H3K27ac(24-27) peptide, Protein ENL
著者Li, Y, Peng, B, Li, H.
登録日2022-03-12
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
Mol.Cell, 82, 2022
5Z30
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The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A.Z, ...
著者Horikoshi, N, Arimura, Y, Kurumizaka, H.
登録日2018-01-05
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
2B2T
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BU of 2b2t by Molmil
Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
3UEF
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Crystal structure of human Survivin bound to histone H3 (C2 space group).
分子名称: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, N-terminal fragment of histone H3, ...
著者Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W.
登録日2011-10-30
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol.Biol.Cell, 23, 2012
6AZE
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Crystal Structure of the BPTF PHD-bromodomain module bound to H3KC4me3 methyl lysine analog
分子名称: ALA-ARG-THR-ML3-GLN-THR, Nucleosome-remodeling factor subunit BPTF, ZINC ION
著者Chen, Z, Ruthenburg, A.J.
登録日2017-09-11
公開日2018-09-19
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Quantitative and structural assessment of methyllysine analog engagement by cognate binding proteins reveals decrements that can impact qualitative experiment interpretation
To be published
3QO2
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Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9
分子名称: 1,2-ETHANEDIOL, Histone H3 peptide, M-phase phosphoprotein 8
著者Chang, Y, Horton, J.R, Bedford, M.T, Zhang, X, Cheng, X.
登録日2011-02-09
公開日2011-04-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding.
J.Mol.Biol., 408, 2011
9FGQ
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Structure of human APC3loop 375-381 bound to the NCP
分子名称: Cell division cycle protein 27 homolog, DNA (131-MER), DNA (132-MER), ...
著者Young, R.V.C, Muhammad, R, Alfieri, C.
登録日2024-05-24
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Spatial control of the APC/C ensures the rapid degradation of Cyclin B1
To be published

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