8U13
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 1) | 分子名称: | DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-08-30 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|
6M44
| 355 bp di-nucleosome harboring cohesive DNA termini (high cryoprotectant) | 分子名称: | CALCIUM ION, DNA (355-MER), Histone H2A type 1-B/E, ... | 著者 | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | 登録日 | 2020-03-05 | 公開日 | 2020-10-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.81 Å) | 主引用文献 | Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
|
|
6LA2
| 343 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | 分子名称: | DNA (343-MER), Histone H1.0, Histone H2A type 1-B/E, ... | 著者 | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | 登録日 | 2019-11-11 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.89 Å) | 主引用文献 | Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
|
|
8W9D
| |
8HAH
| Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (3.9 angstrom resolution) | 分子名称: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
|
|
8SN5
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A) (class 3) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|
8SN9
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 1) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|
8U14
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A lysine 15 in complex with RNF168-UbcH5c (class 2) | 分子名称: | DNA (146-MER), DNA (147-MER), E3 ubiquitin-protein ligase RNF168, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-08-30 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|
6M4H
| Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 | 分子名称: | DNA (103-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ... | 著者 | Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q. | 登録日 | 2020-03-07 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2. Embo J., 40, 2021
|
|
6R8Z
| Cryo-EM structure of NCP_THF2(-1)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
|
|
7C0M
| Human cGAS-nucleosome complex | 分子名称: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1-B/E, ... | 著者 | Kujirai, T, Zierhut, C, Takizawa, Y, Kim, R, Negishi, L, Uruma, N, Hirai, S, Funabiki, H, Kurumizaka, H. | 登録日 | 2020-05-01 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for the inhibition of cGAS by nucleosomes. Science, 370, 2020
|
|
7V96
| Telomeric Dinucleosome | 分子名称: | DNA (275-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Soman, A. | 登録日 | 2021-08-24 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Columnar structure of human telomeric chromatin. Nature, 609, 2022
|
|
7X58
| Cryo-EM structure of human subnucleosome (open form) | 分子名称: | Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... | 著者 | Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-03-04 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7W9V
| Cryo-EM structure of nucleosome in complex with p300 acetyltransferase catalytic core (complex I) | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Hatazawa, S, Liu, J, Takizawa, Y, Zandian, M, Negishi, L, Kutateladze, T.G, Kurumizaka, H. | 登録日 | 2021-12-10 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Structural basis for binding diversity of acetyltransferase p300 to the nucleosome. Iscience, 25, 2022
|
|
7Y00
| Cryo-EM structure of the nucleosome containing 169 base-pair DNA with a p53 target sequence | 分子名称: | DNA (169-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-06-03 | 公開日 | 2022-10-19 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Structural basis for p53 binding to its nucleosomal target DNA sequence. Pnas Nexus, 1, 2022
|
|
7XZY
| Cryo-EM structure of the nucleosome containing 193 base-pair DNA with a p53 target sequence | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-06-03 | 公開日 | 2022-10-19 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structural basis for p53 binding to its nucleosomal target DNA sequence. Pnas Nexus, 1, 2022
|
|
6R93
| Cryo-EM structure of NCP-6-4PP | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
|
|
8SNA
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|
4YM5
| Crystal structure of the human nucleosome containing 6-4PP (inside) | 分子名称: | 144 mer-DNA, 144-mer DNA, Histone H2A type 1-B/E, ... | 著者 | Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H. | 登録日 | 2015-03-06 | 公開日 | 2015-12-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.005 Å) | 主引用文献 | Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome Sci Rep, 5, 2015
|
|
7XZZ
| Cryo-EM structure of the nucleosome in complex with p53 | 分子名称: | Cellular tumor antigen p53, DNA (169-MER), Histone H2A type 1-B/E, ... | 著者 | Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-06-03 | 公開日 | 2022-10-12 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Structural basis for p53 binding to its nucleosomal target DNA sequence. Pnas Nexus, 1, 2022
|
|
8EVJ
| CX3CR1 nucleosome bound PU.1 and C/EBPa | 分子名称: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Guan, R, Bai, Y, Lian, T. | 登録日 | 2022-10-20 | 公開日 | 2023-11-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
|
|
6R91
| Cryo-EM structure of NCP_THF2(-3)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
|
|
7SCY
| Nuc147 bound to single BRCT | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... | 著者 | Muthurajan, U.M, Rudolph, J.R. | 登録日 | 2021-09-29 | 公開日 | 2022-01-12 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol.Cell, 81, 2021
|
|
8XBT
| The cryo-EM structure of the octameric RAD51 ring bound to the nucleosome with the linker DNA binding | 分子名称: | DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-12-07 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
|
|
8YJM
| Structure of human SPT16 MD-CTD and MCM2 HBD chaperoning a histone H3-H4 tetramer and a single chain H2B-H2A chimera | 分子名称: | DNA replication licensing factor MCM2, FACT complex subunit SPT16, Histone H2B 1/2/3/4/6,Histone H2A type 1-D, ... | 著者 | Gan, S.L, Yang, W.S, Xu, R.M. | 登録日 | 2024-03-02 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | 主引用文献 | Structure of a histone hexamer bound by the chaperone domains of SPT16 and MCM2. Sci China Life Sci, 67, 2024
|
|