3UVY
 
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac) | | 分子名称: | Bromodomain-containing protein 4, Histone H4 | | 著者 | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-11-30 | | 公開日 | 2012-01-18 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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3JPX
 | | EED: A Novel Histone Trimethyllysine Binder Within The EED-EZH2 Polycomb Complex | | 分子名称: | HISTONE PEPTIDE, Polycomb protein EED | | 著者 | Xu, C, Bian, C.B, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2009-09-04 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
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5FWE
 | | JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE | | 分子名称: | CHLORIDE ION, GLYCEROL, LYSINE-SPECIFIC DEMETHYLASE 4A, ... | | 著者 | Chowdhury, R, Walport, L.J, Schofield, C.J. | | 登録日 | 2016-02-15 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases.
Nat.Commun., 7, 2016
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4H9O
 | | Complex structure 2 of DAXX/H3.3(sub5,G90M)/H4 | | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | | 登録日 | 2012-09-24 | | 公開日 | 2012-10-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
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4GQB
 | | Crystal Structure of the human PRMT5:MEP50 Complex | | 分子名称: | (2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid, Histone H4 peptide, Methylosome protein 50, ... | | 著者 | Antonysamy, S, Bonday, Z, Campbell, R, Doyle, B, Druzina, Z, Gheyi, T, Han, B, Jungheim, L.N, Qian, Y, Rauch, C, Russell, M, Sauder, J.M, Wasserman, S.R, Weichert, K, Willard, F.S, Zhang, A, Emtage, S. | | 登録日 | 2012-08-22 | | 公開日 | 2012-10-17 | | 最終更新日 | 2018-11-21 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Crystal structure of the human PRMT5:MEP50 complex.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5Y0C
 | | Crystal Structure of the human nucleosome at 2.09 angstrom resolution | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | | 著者 | Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M. | | 登録日 | 2017-07-16 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.087 Å) | | 主引用文献 | Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
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4YYG
 | | Crystal structure of BRD9 Bromodomain bound to a butyryllysine peptide | | 分子名称: | Bromodomain-containing protein 9, Histone H4 | | 著者 | Tang, Y, Bellon, S, Cochran, A.G, Poy, F. | | 登録日 | 2015-03-23 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.
Structure, 23, 2015
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3IJ1
 | | Crystal structure of Eed in complex with a trimethylated histone H4K20 peptide | | 分子名称: | Histone H4K20 peptide, Polycomb protein EED | | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
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3NQJ
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6JOU
 | | Crystal structure of the human nucleosome containing H2A.Z.1 S42R | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | | 著者 | Horikoshi, N, Sato, K, Mizukami, Y, Kurumizaka, H. | | 登録日 | 2019-03-23 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo.
Biochem.Biophys.Res.Commun., 515, 2019
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8Q3E
 | | High Resolution Structure of Nucleosome Core with Bound Foamy Virus GAG Peptide | | 分子名称: | DNA (145-MER), GLY-GLY-TYR-ASN-LEU-ARG-PRO-ARG-THR-TYR-GLN-PRO-GLN-ARG-TYR-GLY-GLY-GLY, Histone H2A type 1-B/E, ... | | 著者 | De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A. | | 登録日 | 2023-08-04 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.174 Å) | | 主引用文献 | Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
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5X7X
 | | The crystal structure of the nucleosome containing H3.3 at 2.18 angstrom resolution | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | | 著者 | Arimura, Y, Taguchi, H, Kurumizaka, H. | | 登録日 | 2017-02-27 | | 公開日 | 2017-04-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.184 Å) | | 主引用文献 | Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Biochemistry, 56, 2017
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4H9R
 | | Complex structure 5 of DAXX(E225A)/H3.3(sub5,G90A)/H4 | | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | | 登録日 | 2012-09-24 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.197 Å) | | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
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4H9P
 | | Complex structure 3 of DAXX/H3.3(sub5,G90A)/H4 | | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | | 登録日 | 2012-09-24 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out
To be Published
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4M38
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6K1K
 | | Human nucleosome core particle with H2A.X S139E variant | | 分子名称: | CHLORIDE ION, DNA (145-MER), Histone H2AX, ... | | 著者 | Sharma, D, De Falco, L, Davey, C.A. | | 登録日 | 2019-05-10 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
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5AV6
 | | human nucleosome core particle | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. | | 登録日 | 2015-06-12 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
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5AV9
 | | human nucleosome core particle | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. | | 登録日 | 2015-06-12 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
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5AV8
 | | human nucleosome core particle | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. | | 登録日 | 2015-06-12 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
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5B31
 | | The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | | 著者 | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | | 登録日 | 2016-02-08 | | 公開日 | 2016-08-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
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6KVD
 | | Crystal structure of human nucleosome containing H2A.J | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A.J, ... | | 著者 | Tanaka, H, Koyama, M, Sato, S, Kujirai, T, Kurumizaka, H. | | 登録日 | 2019-09-04 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Biochemical and structural analyses of the nucleosome containing human histone H2A.J.
J.Biochem., 167, 2020
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6KE9
 | | The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ... | | 著者 | Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L. | | 登録日 | 2019-07-04 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
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6JXD
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6IQ4
 | | Nucleosome core particle cross-linked with a hetero-binuclear molecule possessing RAPTA and gold(I) 4-(diphenylphosphino)benzoic acid groups. | | 分子名称: | 4-diphenylphosphanylbenzoic acid, DNA (145-MER), GOLD ION, ... | | 著者 | DeFalco, L, Batchelor, L.K, Adhireksan, Z, Dyson, P.J, Davey, C.A. | | 登録日 | 2018-11-06 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crosslinking Allosteric Sites on the Nucleosome.
Angew.Chem.Int.Ed.Engl., 58, 2019
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8KB5
 | | Cryo-EM structure of the human nucleosome containing H3.8 | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Hirai, H, Kujirai, T, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-08-03 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.26133 Å) | | 主引用文献 | Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8.
J.Biochem., 174, 2023
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