Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 176 件
7GA1
DownloadVisualize
BU of 7ga1 by Molmil
PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with POB0128
分子名称: (1S,2R)-2-(thiophen-3-yl)cyclopentane-1-carboxylic acid, 1,2-ETHANEDIOL, PHOSPHATE ION, ...
著者Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F.
登録日2023-07-03
公開日2023-07-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献PanDDA analysis group deposition
To Be Published
5VIM
DownloadVisualize
BU of 5vim by Molmil
Crystal structure of the Zika virus NS5 methyltransferase.
分子名称: Methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION
著者Bukrejewska, M, Derewenda, Z.S, Derewenda, U.
登録日2017-04-17
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Acta Crystallogr D Struct Biol, 73, 2017
7G9Q
DownloadVisualize
BU of 7g9q by Molmil
PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z751811134
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, N,N-dimethylpyridine-3-sulfonamide, ...
著者Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F.
登録日2023-07-03
公開日2023-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.131 Å)
主引用文献PanDDA analysis group deposition
To Be Published
7ZMI
DownloadVisualize
BU of 7zmi by Molmil
Crystal Structure of Unlinked NS2B_NS3 Protease from Zika Virus in Complex with Inhibitor MI-2113
分子名称: (2~{R})-6-[[(2~{S})-6-azanyl-2-[[(2~{S})-6-azanyl-2-(2-phenylethanoylamino)hexanoyl]amino]hexanoyl]amino]-2-carbamimidamido-hexanoic acid, Serine protease NS3, Serine protease subunit NS2B
著者Huber, S, Steinmetzer, T.
登録日2022-04-19
公開日2022-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Thermodynamic characterization of a macrocyclic Zika virus NS2B/NS3 protease inhibitor and its acyclic analogs.
Arch Pharm, 356, 2023
6ADW
DownloadVisualize
BU of 6adw by Molmil
Crystal structure of the Zika virus NS3 helicase (apo form)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Serine protease NS3
著者Fang, J, Lu, G, Gong, P.
登録日2018-08-02
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
ACS Infect Dis, 5, 2019
5W41
DownloadVisualize
BU of 5w41 by Molmil
Zika MR766 NLS in complex with Importin alpha subunit-1
分子名称: Importin subunit alpha-1, ZIKA MR766 NLS
著者Jeffress, S, Smith, K.M, Forwood, J.K.
登録日2017-06-08
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells.
ACS Infect Dis, 2019
7VLI
DownloadVisualize
BU of 7vli by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound MI2220
分子名称: 1-[(3~{S},6~{S},19~{R})-3,6-bis(4-azanylbutyl)-2,5,8,12,15,18-hexakis(oxidanylidene)-1,4,7,11,14,17-hexazacyclotricos-19-yl]guanidine, NS3 protease, SULFATE ION, ...
著者Quek, J.P.
登録日2021-10-02
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.385 Å)
主引用文献Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors.
J.Med.Chem., 65, 2022
5TFO
DownloadVisualize
BU of 5tfo by Molmil
CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS2B-NS3 PROTEASE with a deletion V76-L86 in NS2b
分子名称: NS2B-NS3 Protease CHIMERA,NS2B-NS3 PROTEASE,NS2B-NS3 Protease CHIMERA
著者Aleshin, A.E, Bankston, L, Liddington, R.C.
登録日2016-09-26
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献A novel conformation for the Zika virus NS2B-NS3 protease offers new insights into biological regulation and inhibitor design.
To Be Published
5GXJ
DownloadVisualize
BU of 5gxj by Molmil
Zika Virus NS2B-NS3 protease
分子名称: FLAVIVIRUS_NS2B,LINKER,Peptidase S7
著者Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K.
登録日2016-09-18
公開日2017-05-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Viral protease activation mechanism
To Be Published
6KPQ
DownloadVisualize
BU of 6kpq by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 8
分子名称: 1-[(10~{R},17~{S},20~{S})-17,20-bis(4-azanylbutyl)-4,9,16,19,22-pentakis(oxidanylidene)-3,8,15,18,21-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-trien-10-yl]guanidine, NS3 protease, Serine protease subunit NS2B
著者Quek, J.P.
登録日2019-08-15
公開日2020-06-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure-Based Macrocyclization of Substrate Analogue NS2B-NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses.
Chemmedchem, 15, 2020
7VLH
DownloadVisualize
BU of 7vlh by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound MI2219
分子名称: 1-[(3~{S},6~{R},18~{R})-3,6-bis(4-azanylbutyl)-2,5,8,11,14,17-hexakis(oxidanylidene)-1,4,7,10,13,16-hexazacyclodocos-18-yl]guanidine, NS3 protease, SULFATE ION, ...
著者Quek, J.P.
登録日2021-10-02
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.621 Å)
主引用文献Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors.
J.Med.Chem., 65, 2022
8WO4
DownloadVisualize
BU of 8wo4 by Molmil
ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者Chew, B.L.A, Luo, D.
登録日2023-10-06
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
5Z0V
DownloadVisualize
BU of 5z0v by Molmil
Structural insight into the Zika virus capsid encapsulating the viral genome
分子名称: Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H.
登録日2017-12-21
公開日2018-04-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.913 Å)
主引用文献Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
5U0C
DownloadVisualize
BU of 5u0c by Molmil
Structure of Zika virus NS5 RNA polymerase domain
分子名称: NS5 RNA polymerase domain, ZINC ION
著者Zhao, B, Du, F.
登録日2016-11-23
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and function of the Zika virus full-length NS5 protein.
Nat Commun, 8, 2017
8WN8
DownloadVisualize
BU of 8wn8 by Molmil
CryoEM structure of ZIKV rsNS1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1
著者Chew, B.L.A, Luo, D.
登録日2023-10-05
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
5U0B
DownloadVisualize
BU of 5u0b by Molmil
Structure of full-length Zika virus NS5
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Zhao, B, Du, F.
登録日2016-11-23
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and function of the Zika virus full-length NS5 protein.
Nat Commun, 8, 2017
5TFN
DownloadVisualize
BU of 5tfn by Molmil
CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS2B-NS3 PROTEASE in super-open conformation
分子名称: NS2B-NS3 Protease CHIMERA,Genome polyprotein
著者Aleshin, A.E, Bankston, L, Liddington, R.C.
登録日2016-09-26
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A novel conformation for the Zika virus NS2B-NS3 protease offers new insights into biological regulation and inhibitor design.
To Be Published
6UX2
DownloadVisualize
BU of 6ux2 by Molmil
Crystal structure of ZIKV RdRp in complex with STAT2
分子名称: Nonstructural Protein 5, SULFATE ION, Signal transducer and activator of transcription 2, ...
著者Wang, B, Song, J.
登録日2019-11-06
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural basis for STAT2 suppression by flavivirus NS5.
Nat.Struct.Mol.Biol., 27, 2020
5TFR
DownloadVisualize
BU of 5tfr by Molmil
Crystal structure of Zika Virus NS5 protein
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Longenecker, K.L, Upadhyay, A.K.
登録日2016-09-26
公開日2016-10-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5T1V
DownloadVisualize
BU of 5t1v by Molmil
Crystal structure of Zika virus NS2B-NS3 protease in apo-form.
分子名称: NS2B-NS3 protease,NS2B-NS3 protease
著者Nocadello, S, Light, S.H, Minasov, G, Shuvalova, L, Cardona-Correa, A.A, Ojeda, I, Vargas, J, Johnson, M.E, Lee, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-08-22
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of Zika virus NS2B-NS3 protease in apo-form.
To Be Published
8WNP
DownloadVisualize
BU of 8wnp by Molmil
ZIKV rsNS1 in complex with Fab AA12 and anti-fab nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者Chew, B.L.A, Luo, D.
登録日2023-10-06
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
5TMH
DownloadVisualize
BU of 5tmh by Molmil
Structure of Zika virus NS5
分子名称: GLYCEROL, Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Wang, B, Tan, X, Song, J.
登録日2016-10-12
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.278 Å)
主引用文献The structure of Zika virus NS5 reveals a conserved domain conformation.
Nat Commun, 8, 2017
7JYI
DownloadVisualize
BU of 7jyi by Molmil
Subparticle Map of ZIKV MR-766
分子名称: E Glycoprotein, M protein
著者Jose, J, Hafenstein, S.
登録日2020-08-30
公開日2020-09-16
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Identification of a pocket factor that is critical to Zika virus assembly.
Nat Commun, 11, 2020
8WNU
DownloadVisualize
BU of 8wnu by Molmil
ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者Chew, B.L.A, Luo, D.
登録日2023-10-06
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
6WCZ
DownloadVisualize
BU of 6wcz by Molmil
CryoEM structure of full-length ZIKV NS5-hSTAT2 complex
分子名称: Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION
著者Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S.
登録日2020-03-31
公開日2020-07-08
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for STAT2 suppression by flavivirus NS5.
Nat.Struct.Mol.Biol., 27, 2020

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon