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PDB: 70 件

6MID
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BU of 6mid by Molmil
Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ...
著者Long, F, Rossmann, M.G.
登録日2018-09-19
公開日2019-01-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
7KCR
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Cryo-EM structure of Zika virus in complex with E protein cross-linking human monoclonal antibody ADI30056
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADI30056 Fab heavy chain variable region, ADI30056 Fab light chain variable region, ...
著者Sevvana, M, Rogers, T.F, Miller, A.S, Long, F, Klose, T, Beutler, N, Lai, Y.C, Parren, M, Walker, L.M, Buda, G, Burton, D.R, Rossmann, M.G, Kuhn, R.J.
登録日2020-10-07
公開日2020-12-16
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections.
Viruses, 12, 2020
5H37
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BU of 5h37 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ...
著者Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M.
登録日2016-10-20
公開日2016-11-30
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
7CBP
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BU of 7cbp by Molmil
CryoEM structure of Zika virus with Fab at 4.1 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, Fab Heavy chain, ...
著者Tyagi, A, Ahmed, T, Shi, J, Bhushan, S.
登録日2020-06-13
公開日2020-07-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 angstrom resolution.
J Struct Biol X, 4, 2020
6NIP
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BU of 6nip by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E glycoprotein
分子名称: Envelope protein E, MZ1 Heavy chain, MZ1 Light Chain
著者Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
登録日2018-12-31
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.16 Å)
主引用文献Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat Med, 26, 2020
6NIU
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BU of 6niu by Molmil
Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein
分子名称: Envelope protein E, Human MZ4 Fab heavy chain, Human MZ4 Fab light chain
著者Sankhala, R.S, Dussupt, V, Donofrio, G, Choe, M, Modjarrad, K, Michael, N.L, Krebs, S.J, Joyce, M.G.
登録日2018-12-31
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.303 Å)
主引用文献Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor.
Nat. Med., 26, 2020
5H30
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BU of 5h30 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5
分子名称: IgG C10 heavy chain, IgG C10 light chain, structural protein E, ...
著者Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
登録日2016-10-19
公開日2016-11-30
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
7BUA
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BU of 7bua by Molmil
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SIgN-3C Fab heavy chain, ...
著者Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M.
登録日2020-04-06
公開日2020-05-13
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms.
Cell Rep, 31, 2020
7T17
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Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment
分子名称: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ...
著者Miller, A.S, Kuhn, R.J.
登録日2021-12-01
公開日2022-11-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5.26 Å)
主引用文献A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization.
Cell, 185, 2022
7YAR
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BU of 7yar by Molmil
ZIKV_Fab_G9E
分子名称: E protein, M protein, heavy chain, ...
著者Shu, B, Thiam-Seng, N, Lok, S.
登録日2022-06-28
公開日2023-01-04
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.
Plos Pathog., 19, 2023
5UHY
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BU of 5uhy by Molmil
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
分子名称: ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
著者Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G.
登録日2017-01-12
公開日2017-03-29
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
6LNT
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BU of 6lnt by Molmil
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
分子名称: Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ...
著者Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M.
登録日2020-01-02
公開日2020-02-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
6LNU
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BU of 6lnu by Molmil
Cryo-EM structure of immature Zika virus
分子名称: Genome polyprotein
著者Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M.
登録日2020-01-02
公開日2020-02-26
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
5U4W
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BU of 5u4w by Molmil
Cryo-EM Structure of Immature Zika Virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ...
著者Mangala Prasad, V, Miller, A.S, Klose, T, Sirohi, D, Buda, G, Jiang, W, Kuhn, R.J, Rossmann, M.G.
登録日2016-12-06
公開日2017-01-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献Structure of the immature Zika virus at 9 angstrom resolution.
Nat. Struct. Mol. Biol., 24, 2017
7C2T
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BU of 7c2t by Molmil
Helical reconstruction of Zika virus complexed with Fab C10
分子名称: Heavy chain from Fab C10, Light chain from Fab C10, M protein, ...
著者Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M.
登録日2020-05-09
公開日2020-07-08
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献High flavivirus structural plasticity demonstrated by a non-spherical morphological variant.
Nat Commun, 11, 2020
5GZR
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BU of 5gzr by Molmil
Zika virus E protein complexed with a neutralizing antibody Z23-Fab
分子名称: Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ...
著者Gao, G.G, Shi, Y, Peng, R, Liu, S.
登録日2016-10-01
公開日2016-11-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
6JFI
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BU of 6jfi by Molmil
The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex
分子名称: FabZK2B10 heavy chain, FabZK2B10 light chain, ZIKV structural protein E, ...
著者Wang, L, Wang, R.K, Wang, L, Ben, H.J, Yu, L, Gao, F, Shi, X.L, Yin, C.B, Zhang, F.C, Xiang, Y, Zhang, L.Q.
登録日2019-02-08
公開日2019-04-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
5H32
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BU of 5h32 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0
分子名称: C10 IgG heavy chain variable region, C10 IgG light chain variable region, structural protein E
著者Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
登録日2016-10-20
公開日2016-11-30
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
6JFH
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BU of 6jfh by Molmil
The asymmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex
分子名称: FabZK2B10 heavy chain, FabZK2B10 light chain, ZIKV structural E protein, ...
著者Wang, L, Wang, R.K, Wang, L, Ben, H.J, Yu, L, Gao, F, Shi, X.L, Yin, C.B, Zhang, F.C, Xiang, Y, Zhang, L.Q.
登録日2019-02-08
公開日2019-04-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody.
Cell Rep, 26, 2019
5Y0A
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BU of 5y0a by Molmil
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
分子名称: protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
著者Wang, J.Q, Lok, S.M.
登録日2017-07-15
公開日2017-10-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
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