7KCR

Cryo-EM structure of Zika virus in complex with E protein cross-linking human monoclonal antibody ADI30056

Summary for 7KCR

• Entry DOI: 10.2210/pdb7kcr/pdb
• EMDB information: 22818
• Descriptor: ADI30056 Fab heavy chain variable region, ADI30056 Fab light chain variable region, envelope protein E, ... (5 entities in total)
• Functional Keywords: zika virus, flavivirus, zika-antibody, virus-immune system complex, virus/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 214176.87

Authors

Sevvana, M.,Rogers, T.F.,Miller, A.S.,Long, F.,Klose, T.,Beutler, N.,Lai, Y.C.,Parren, M.,Walker, L.M.,Buda, G.,Burton, D.R.,Rossmann, M.G.,Kuhn, R.J. (deposition date: 2020-10-07, release date: 2020-12-16)

• Primary citation: Sevvana, M.,Rogers, T.F.,Miller, A.S.,Long, F.,Klose, T.,Beutler, N.,Lai, Y.C.,Parren, M.,Walker, L.M.,Buda, G.,Burton, D.R.,Rossmann, M.G.,Kuhn, R.J.; Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections.; Viruses, 12:-, 2020; PubMed: 33255202; DOI: 10.3390/v12121346

Experimental method

ELECTRON MICROSCOPY (4 Å)