1TYN
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![BU of 1tyn by Molmil](/molmil-images/mine/1tyn) | ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS | Descriptor: | BETA-TRYPSIN, CYCLOTHEONAMIDE A | Authors: | Lee, A.Y, Hagihara, M, Karmacharya, R, Albers, M.W, Schreiber, S.L, Clardy, J. | Deposit date: | 1994-09-19 | Release date: | 1995-01-26 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic Structure of the Trypsin-Cyclotheonamide a Complex: Lessons for the Design of Serine Protease Inhibitors J.Am.Chem.Soc., 115, 1993
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2KLI
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![BU of 2kli by Molmil](/molmil-images/mine/2kli) | Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form | Descriptor: | PHYCOCYANOBILIN, Sensor protein | Authors: | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Zhang, J, Rivera, M, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2009-07-03 | Release date: | 2009-11-03 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structural basis for the photoconversion of a phytochrome to the activated Pfr form Nature, 463, 2010
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2CE2
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![BU of 2ce2 by Molmil](/molmil-images/mine/2ce2) | CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP | Descriptor: | GTPASE HRAS, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Klink, B.U, Goody, R.S, Scheidig, A.J. | Deposit date: | 2006-02-02 | Release date: | 2006-08-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | A Newly Designed Microspectrofluorometer for Kinetic Studies on Protein Crystals in Combination with X-Ray Diffraction Biophys.J., 91, 2006
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2E2R
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![BU of 2e2r by Molmil](/molmil-images/mine/2e2r) | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol A | Descriptor: | 4,4'-PROPANE-2,2-DIYLDIPHENOL, Estrogen-related receptor gamma, GLYCEROL | Authors: | Matsushima, A, Kakuta, Y, Teramoto, T, Koshiba, T, Kimura, M, Shimohigashi, Y. | Deposit date: | 2006-11-16 | Release date: | 2007-09-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERR{gamma} J.Biochem.(Tokyo), 142, 2007
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1JEG
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![BU of 1jeg by Molmil](/molmil-images/mine/1jeg) | Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP | Descriptor: | HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK | Authors: | Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D. | Deposit date: | 2001-06-17 | Release date: | 2001-10-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A novel, specific interaction involving the Csk SH3 domain and its natural ligand. Nat.Struct.Biol., 8, 2001
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2B58
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![BU of 2b58 by Molmil](/molmil-images/mine/2b58) | SSAT with coa_sp, spermine disordered, K26R mutant | Descriptor: | COENZYME A, Diamine acetyltransferase 1 | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-27 | Release date: | 2006-01-24 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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2B4D
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![BU of 2b4d by Molmil](/molmil-images/mine/2b4d) | SSAT+COA+SP- SP disordered | Descriptor: | COENZYME A, Diamine acetyltransferase 1 | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-23 | Release date: | 2006-01-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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2B3V
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![BU of 2b3v by Molmil](/molmil-images/mine/2b3v) | Spermine spermidine acetyltransferase in complex with acetylcoa, K26R mutant | Descriptor: | ACETYL COENZYME *A, Diamine acetyltransferase 1 | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-21 | Release date: | 2006-01-17 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. Proc.Natl.Acad.Sci.USA, 103, 2006
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2B4B
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![BU of 2b4b by Molmil](/molmil-images/mine/2b4b) | SSAT+COA+BE-3-3-3, K26R mutant | Descriptor: | COENZYME A, Diamine acetyltransferase 1, N-ETHYL-N-[3-(PROPYLAMINO)PROPYL]PROPANE-1,3-DIAMINE | Authors: | Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-09-23 | Release date: | 2006-01-17 | Last modified: | 2023-05-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
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2CS7
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![BU of 2cs7 by Molmil](/molmil-images/mine/2cs7) | |
2LB5
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![BU of 2lb5 by Molmil](/molmil-images/mine/2lb5) | Refined Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form | Descriptor: | PHYCOCYANOBILIN, Sensor histidine kinase | Authors: | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L. | Deposit date: | 2011-03-23 | Release date: | 2011-06-29 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis for the photoconversion of a phytochrome to the activated Pfr form. Nature, 463, 2010
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3U6T
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![BU of 3u6t by Molmil](/molmil-images/mine/3u6t) | Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, KANAMYCIN A, ... | Authors: | Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2011-10-13 | Release date: | 2011-11-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the complex of type I Ribosome inactivating protein in complex with Kanamycin at 1.85 A To be Published
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2EZV
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![BU of 2ezv by Molmil](/molmil-images/mine/2ezv) | Crystal structure of tetrameric restriction endonuclease SfiI bound to cognate DNA. | Descriptor: | 5'-D(*AP*GP*GP*CP*CP*TP*TP*GP*TP*TP*GP*GP*CP*CP*A)-3', 5'-D(*TP*GP*GP*CP*CP*AP*AP*CP*AP*AP*GP*GP*CP*CP*T)-3', CALCIUM ION, ... | Authors: | Aggarwal, A.K, Vanamee, E.S, Viadiu, H. | Deposit date: | 2005-11-10 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA Embo J., 24, 2005
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2EWJ
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![BU of 2ewj by Molmil](/molmil-images/mine/2ewj) | Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- Locked form | Descriptor: | 5'-D(*T*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*CP*T)-3', 5'-D(*TP*G*AP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3', DNA replication terminus site-binding protein, ... | Authors: | Oakley, A.J, Mulcair, M.D, Schaeffer, P.M, Dixon, N.E. | Deposit date: | 2005-11-03 | Release date: | 2006-05-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A molecular mousetrap determines polarity of termination of DNA replication in E. coli. Cell(Cambridge,Mass.), 125, 2006
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2CTB
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![BU of 2ctb by Molmil](/molmil-images/mine/2ctb) | THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE | Descriptor: | CARBOXYPEPTIDASE A, ZINC ION | Authors: | Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S. | Deposit date: | 1993-04-02 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate. Acta Crystallogr.,Sect.D, 49, 1993
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2OVM
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![BU of 2ovm by Molmil](/molmil-images/mine/2ovm) | Progesterone Receptor with Bound Asoprisnil and a Peptide from the Co-Repressor NCoR | Descriptor: | 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDE OXIME, NCoR, Progesterone receptor | Authors: | Madauss, K.P, Deng, S.-J, Short, S.A, Stewart, E.L, Williams, S.P. | Deposit date: | 2007-02-14 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator. Mol.Endocrinol., 21, 2007
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2N70
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![BU of 2n70 by Molmil](/molmil-images/mine/2n70) | Two-fold symmetric structure of the 18-60 construct of S31N M2 from Influenza A in lipid bilayers | Descriptor: | Matrix protein 2 | Authors: | Andreas, L.B, Reese, M, Eddy, M.T, Gelev, V, Ni, Q, Miller, E.A, Emsley, L, Pintacuda, G, Chou, J.J, Griffin, R.G. | Deposit date: | 2015-09-01 | Release date: | 2015-09-23 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structure and Mechanism of the Influenza A M218-60 Dimer of Dimers. J.Am.Chem.Soc., 137, 2015
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2CTC
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![BU of 2ctc by Molmil](/molmil-images/mine/2ctc) | THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE | Descriptor: | ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CARBOXYPEPTIDASE A, ZINC ION | Authors: | Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S. | Deposit date: | 1993-04-02 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate. Acta Crystallogr.,Sect.D, 49, 1993
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2N17
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![BU of 2n17 by Molmil](/molmil-images/mine/2n17) | NMR structure of a Kazal-type serine protease inhibitor from the subterranean termite defense gland of Coptotermes formosanus Shiraki soldiers | Descriptor: | Lysozyme-Protease Inhibitor Protein | Authors: | Negulescu, H, Guo, Y, Garner, T.P, Goodwin, O.Y, Henderson, G, Laine, R.A, Macnaughtan, M.A. | Deposit date: | 2015-03-23 | Release date: | 2015-05-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki. Plos One, 10, 2015
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2HWN
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![BU of 2hwn by Molmil](/molmil-images/mine/2hwn) | |
2H67
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![BU of 2h67 by Molmil](/molmil-images/mine/2h67) | NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Hua, Q.X, Liu, M, Hu, S.Q, Jia, W, Arvan, P, Weiss, M.A. | Deposit date: | 2006-05-30 | Release date: | 2006-07-18 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | A Conserved Histidine in Insulin Is Required for the Foldability of Human Proinsulin: Structure and function of an Alab5 analog. J.Biol.Chem., 281, 2006
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1N33
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![BU of 1n33 by Molmil](/molmil-images/mine/1n33) | Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer rna anticodon stem-loop mismatched at the second codon position at the a site with paromomycin | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V. | Deposit date: | 2002-10-25 | Release date: | 2002-11-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form Cell(Cambridge,Mass.), 111, 2002
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1VZK
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![BU of 1vzk by Molmil](/molmil-images/mine/1vzk) | A Thiophene Based Diamidine Forms a "Super" AT Binding Minor Groove Agent | Descriptor: | 2-(5-{4-[AMINO(IMINO)METHYL]PHENYL}-2-THIENYL)-1H-BENZIMIDAZOLE-6- CARBOXIMIDAMIDE DIHYDROCHLORIDE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP *CP*G)-3', MAGNESIUM ION | Authors: | Mallena, S, Lee, M.P.H, Bailly, C, Neidle, S, Kumar, A, Boykin, D.W, Wilson, W.D. | Deposit date: | 2004-05-20 | Release date: | 2004-10-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Thiophene-Based Diamidine Forms a "Super" at Binding Minor Groove Agent J.Am.Chem.Soc., 142, 2004
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1E8L
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![BU of 1e8l by Molmil](/molmil-images/mine/1e8l) | NMR solution structure of hen lysozyme | Descriptor: | LYSOZYME | Authors: | Schwalbe, H, Grimshaw, S.B, Spencer, A, Buck, M, Boyd, J, Dobson, C.M, Redfield, C, Smith, L.J. | Deposit date: | 2000-09-27 | Release date: | 2000-10-09 | Last modified: | 2018-01-24 | Method: | SOLUTION NMR | Cite: | A refined solution structure of hen lysozyme determined using residual dipolar coupling data. Protein Sci., 10, 2001
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1N49
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![BU of 1n49 by Molmil](/molmil-images/mine/1n49) | Viability of a Drug-Resistant HIV-1 Protease Variant: Structural Insights for Better Anti-Viral Therapy | Descriptor: | Protease, RITONAVIR | Authors: | Prabu-Jeyabalan, M, Nalivaika, E.A, King, N.M, Schiffer, C.A. | Deposit date: | 2002-10-30 | Release date: | 2003-01-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Viability of a Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variant:
Structural Insights for Better Antiviral Therapy J.VIROL., 77, 2003
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