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PDB: 9 results

4LV8
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BU of 4lv8 by Molmil
Murine IRGa6 bound to Toxoplasma ROP5C, a pseudokinase GDI
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Reese, M.L, Boothroyd, J.C.
Deposit date:2013-07-26
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Murine IRGa6 bound to Toxoplasma ROP5C, a pseudokinase GDI
To be Published
4LV5
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BU of 4lv5 by Molmil
Murine IRGa6 bound to Toxoplasma ROP5B, a pseudokinase GDI
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BETA-MERCAPTOETHANOL, ...
Authors:Reese, M.L, Boothroyd, J.C.
Deposit date:2013-07-25
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Murine IRGa6 bound to Toxoplasma ROP5B, a pseudokinase GDI
To be Published
3Q5Z
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BU of 3q5z by Molmil
Crystal structure of virulent allele ROP5B pseudokinase domain
Descriptor: 1,2-ETHANEDIOL, ROP5B
Authors:Reese, M.L, Boothroyd, J.C.
Deposit date:2010-12-30
Release date:2011-02-23
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence.
J.Biol.Chem., 286, 2011
3Q60
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BU of 3q60 by Molmil
Crystal structure of virulent allele ROP5B pseudokinase domain bound to ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MALONATE ION, ...
Authors:Reese, M.L, Boothroyd, J.C.
Deposit date:2010-12-30
Release date:2011-02-23
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence.
J.Biol.Chem., 286, 2011
4XLL
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BU of 4xll by Molmil
Toxoplasma gondii DJ-1, oxidized
Descriptor: DJ-1 family protein
Authors:Child, M.A, Wilson, M.A, Reese, M.L, Bogyo, M.
Deposit date:2015-01-13
Release date:2015-02-11
Last modified:2016-07-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Toxoplasma DJ-1 regulates microneme exocytosis through an association with the plant-like kinase, CDPK1
To Be Published
6M7Z
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BU of 6m7z by Molmil
A divergent kinase lacking the glycine-rich loop regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole
Descriptor: 1,2-ETHANEDIOL, Bradyzoite pseudokinase 1, CHLORIDE ION
Authors:Beraki, T, Borek, D.M, Reese, M.L.
Deposit date:2018-08-21
Release date:2018-10-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Divergent kinase regulates membrane ultrastructure of theToxoplasmaparasitophorous vacuole.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3UE8
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BU of 3ue8 by Molmil
Kynurenine Aminotransferase II Inhibitors
Descriptor: (5-hydroxy-4-{[(1-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Kynurenine/alpha-aminoadipate aminotransferase, ...
Authors:Dounay, A.B, Anderson, M, Bechle, B.M, Campbell, B.M, Claffey, M.M, Evdokimov, A, Edelweiss, E, Fonseca, K.R, Gan, X, Ghosh, S, Hayward, M.M, Horner, W, Kim, J.Y, McAllister, L.A, Pandit, J, Paradis, V, Parikh, V.D, Reese, M.R, Rong, S.B, Salafia, M.A, Schuyten, K, Strick, C.A, Tuttle, J.B, Valentine, J, Wang, H, Zawadzke, L.E, Verhoest, P.R.
Deposit date:2011-10-28
Release date:2012-02-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.
ACS Med Chem Lett, 3, 2012
6V6A
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BU of 6v6a by Molmil
Inhibitory scaffolding of the ancient MAPK, ERK7
Descriptor: 1,2-ETHANEDIOL, Apical Cap Protein 9 (AC9), Mitogen-activated protein kinase
Authors:Dewangan, P.S, O'Shaughnessy, W.J, Back, P.S, Hu, X, Bradley, P.J, Reese, M.L.
Deposit date:2019-12-04
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required forToxoplasmaapical complex biogenesis.
Proc.Natl.Acad.Sci.USA, 117, 2020
2N70
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BU of 2n70 by Molmil
Two-fold symmetric structure of the 18-60 construct of S31N M2 from Influenza A in lipid bilayers
Descriptor: Matrix protein 2
Authors:Andreas, L.B, Reese, M, Eddy, M.T, Gelev, V, Ni, Q, Miller, E.A, Emsley, L, Pintacuda, G, Chou, J.J, Griffin, R.G.
Deposit date:2015-09-01
Release date:2015-09-23
Last modified:2023-06-14
Method:SOLID-STATE NMR
Cite:Structure and Mechanism of the Influenza A M218-60 Dimer of Dimers.
J.Am.Chem.Soc., 137, 2015

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