2E2R

Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol A

Summary for 2E2R

Entry DOI	10.2210/pdb2e2r/pdb
Descriptor	Estrogen-related receptor gamma, 4,4'-PROPANE-2,2-DIYLDIPHENOL, GLYCEROL, ... (4 entities in total)
Functional Keywords	err gamma, bpa, nuclear receptor, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus (Probable): P62508
Total number of polymer chains	1
Total formula weight	28115.70
Authors	Matsushima, A.,Kakuta, Y.,Teramoto, T.,Koshiba, T.,Kimura, M.,Shimohigashi, Y. (deposition date: 2006-11-16, release date: 2007-09-11, Last modification date: 2023-10-25)
Primary citation	Matsushima, A.,Kakuta, Y.,Teramoto, T.,Koshiba, T.,Liu, X.,Okada, H.,Tokunaga, T.,Kawabata, S.,Kimura, M.,Shimohigashi, Y. Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERR{gamma} J.Biochem.(Tokyo), 142:517-524, 2007 Cited by PubMed: 17761695 DOI: 10.1093/jb/mvm158 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation