2E2R
Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Estrogen-related receptor gamma | polymer | 244 | 27611.1 | 1 | UniProt (P62508) Pfam (PF00104) | Homo sapiens (human) | Estrogen receptor-related protein 3, ERR gamma-2 |
| 2 | B (A) | 4,4'-PROPANE-2,2-DIYLDIPHENOL | non-polymer | 228.3 | 1 | Chemie (2OH) | |||
| 3 | C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F (A) | water | water | 18.0 | 387 | Chemie (HOH) |
Sequence modifications
A: 222 - 458 (UniProt: P62508)
| PDB | External Database | Details |
|---|---|---|
| Leu 216 | - | expression tag |
| Gly 217 | - | expression tag |
| Ser 218 | - | expression tag |
| Pro 219 | - | expression tag |
| Glu 220 | - | expression tag |
| Phe 221 | - | expression tag |
| Cys 459 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27611.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 504.6 | |
| All* | Total formula weight | 28115.7 |
