5UE6
| Structure of nitrite reductase AniA from Neisseria gonorrhoeae, space group I4122 | Descriptor: | COPPER (II) ION, Nitrite reductase, SODIUM ION | Authors: | Hamza, A, Williamson, Z.A, Reed, R.W, Sikora, A.E, Korotkov, K.V. | Deposit date: | 2016-12-29 | Release date: | 2017-02-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Peptide Inhibitors Targeting the Neisseria gonorrhoeae Pivotal Anaerobic Respiration Factor AniA. Antimicrob. Agents Chemother., 61, 2017
|
|
1W9Y
| The structure of ACC oxidase | Descriptor: | 1-AMINOCYCLOPROPANE-1-CARBOXYLATE OXIDASE 1, SULFATE ION | Authors: | Zhang, Z, Ren, J.-S, Clifton, I.J, Schofield, C.J. | Deposit date: | 2004-10-20 | Release date: | 2005-10-26 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure and Mechanistic Implications of 1-Aminocyclopropane-1-Carboxylic Acid Oxidase (the Ethyling Forming Enzyme) Chem.Biol., 11, 2004
|
|
5UDO
| |
5UE3
| proMMP-9desFnII | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Matrix metalloproteinase-9, ... | Authors: | Alexander, R.S, Spurlino, J, Milligan, C. | Deposit date: | 2016-12-29 | Release date: | 2017-09-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation. J. Biol. Chem., 292, 2017
|
|
1WCY
| Crystal Structure Of Human Dipeptidyl Peptidase IV (DPPIV) Complex With Diprotin A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase IV, ... | Authors: | Hiramatsu, H, Yamamoto, A, Kyono, K, Higashiyama, Y, Fukushima, C, Shima, H, Sugiyama, S, Inaka, K, Shimizu, R. | Deposit date: | 2004-05-07 | Release date: | 2005-05-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of human dipeptidyl peptidase IV (DPPIV) complex with diprotin A Biol.Chem., 385, 2004
|
|
1WFS
| Solution Structure of Glia Maturation Factor-gamma from Mus Musculus | Descriptor: | Glia maturation factor gamma | Authors: | Goroncy, A.K, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-26 | Release date: | 2004-11-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structures of actin depolymerizing factor homology domains. Protein Sci., 18, 2009
|
|
5UF8
| Crystal structure of the ARF family small GTPase ARF2 from Candida albicans in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Potential ADP-ribosylation factor | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-01-03 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.872 Å) | Cite: | Crystal structure of the ARF family small GTPase ARF2 from Candida albicans in complex with GDP To Be Published
|
|
1WVU
| |
5UG9
| Crystal structure of the EGFR kinase domain (L858R, T790M, V948R) in complex with a covalent inhibitor N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-(propan-2-yl)-9H-purin-2-yl}pyrrolidin-3-yl]propanamide | Descriptor: | 1,2-ETHANEDIOL, Epidermal growth factor receptor, GLYCEROL, ... | Authors: | Gajiwala, K.S, Ferre, R.A. | Deposit date: | 2017-01-07 | Release date: | 2017-03-22 | Last modified: | 2018-10-10 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. J. Med. Chem., 60, 2017
|
|
1WXC
| Crystal Structure of the copper-free Streptomyces castaneoglobisporus tyrosinase complexed with a caddie protein | Descriptor: | MelC, NITRATE ION, tyrosinase | Authors: | Matoba, Y, Kumagai, T, Yamamoto, A, Yoshitsu, H, Sugiyama, M. | Deposit date: | 2005-01-20 | Release date: | 2006-01-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis J.Biol.Chem., 281, 2006
|
|
1WKO
| |
5UEK
| |
1WZF
| Crystal Structure Of An Artificial Metalloprotein: Fe(10-COOH-Salophen)/Wild Type Heme oxygenase | Descriptor: | GLYCEROL, Heme oxygenase, SULFATE ION, ... | Authors: | Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M. | Deposit date: | 2005-03-04 | Release date: | 2006-02-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Design of metal cofactors activated by a protein-protein electron transfer system. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
1WN9
| Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8 | Descriptor: | ACETIC ACID, the hypothetical protein (TT1805) | Authors: | Pioszak, A.A, Kishishita, S, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-07-28 | Release date: | 2005-01-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8 To be Published
|
|
5UE9
| WT DHODB with orotate bound | Descriptor: | CHLORIDE ION, Dihydroorotate dehydrogenase, Dihydroorotate dehydrogenase B (NAD(+)), ... | Authors: | Pompeu, Y.A, Stewart, J.D. | Deposit date: | 2016-12-29 | Release date: | 2017-09-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Isoleucine 74 Plays a Key Role in Controlling Electron Transfer Between Lactococcus lactis Dihydroorotate Dehydrogenase 1B Subunits to be published
|
|
1X27
| Crystal Structure of Lck SH2-SH3 with SH2 binding site of p130Cas | Descriptor: | CRK-associated substrate, Proto-oncogene tyrosine-protein kinase LCK, SODIUM ION | Authors: | Nasertorabi, F, Tars, K, Becherer, K, Kodandapani, R, Liljas, L, Vuori, K, Ely, K.R. | Deposit date: | 2005-04-20 | Release date: | 2006-02-07 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis for regulation of Src by the docking protein p130Cas J.MOL.RECOG., 19, 2006
|
|
5UGX
| |
1W7S
| |
1W8X
| Structural analysis of PRD1 | Descriptor: | MAJOR CAPSID PROTEIN (PROTEIN P3), PROTEIN P16, PROTEIN P30, ... | Authors: | Abrescia, N.G.A, Cockburn, J.J.B, Grimes, J.M, Sutton, G.C, Diprose, J.M, Butcher, S.J, Fuller, S.D, San Martin, C, Burnett, R.M, Stuart, D.I, Bamford, D.H, Bamford, J.K.H. | Deposit date: | 2004-10-01 | Release date: | 2004-11-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Insights Into Assembly from Structural Analysis of Bacteriophage Prd1. Nature, 432, 2004
|
|
5UHO
| |
1VWR
| |
5UHL
| Crystal structure of the core catalytic domain of human O-GlcNAcase complexed with Thiamet G | Descriptor: | (2Z,3aR,5R,6S,7R,7aR)-2-(ethylimino)-5-(hydroxymethyl)hexahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain | Authors: | Klein, D.J, Elsen, N.L. | Deposit date: | 2017-01-11 | Release date: | 2017-03-29 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.14 Å) | Cite: | Crystal structure of the core catalytic domain of human O-GlcNAcase and molecular basis of activity and inhibition To Be Published
|
|
5UGL
| |
5TTB
| |
5UHU
| |