5Z56
| cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | Deposit date: | 2018-01-17 | Release date: | 2018-09-19 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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3WXM
| Crystal structure of archaeal Pelota and GTP-bound EF1 alpha complex | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kobayashi, K, Ishitani, R, Nureki, O. | Deposit date: | 2014-08-04 | Release date: | 2014-09-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1 alpha complex Proc.Natl.Acad.Sci.USA, 107, 2010
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5WE4
| 70S ribosome-EF-Tu wt complex with GppNHp | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Fislage, M, Brown, Z, Frank, J. | Deposit date: | 2017-07-07 | Release date: | 2018-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
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3VNV
| Complex structure of viral RNA polymerase II | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ... | Authors: | Takeshita, D, Tomita, K. | Deposit date: | 2012-01-18 | Release date: | 2012-08-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | Mechanism for template-independent terminal adenylation activity of Q beta replicase Structure, 20, 2012
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5UYN
| 70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | Deposit date: | 2017-02-24 | Release date: | 2017-06-07 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
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4PC2
| Elongation factor Tu:Ts complex with a bound GDP | Descriptor: | CHLORIDE ION, Elongation factor Ts, Elongation factor Tu, ... | Authors: | Thirup, S.S. | Deposit date: | 2014-04-14 | Release date: | 2015-05-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1999 Å) | Cite: | Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu. J.Struct.Biol., 191, 2015
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4Q7J
| Complex structure of viral RNA polymerase | Descriptor: | 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu 1, ... | Authors: | Takeshita, D. | Deposit date: | 2014-04-25 | Release date: | 2014-08-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular insights into replication initiation by Q beta replicase using ribosomal protein S1. Nucleic Acids Res., 42, 2014
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3WY9
| Crystal structure of a complex of the archaeal ribosomal stalk protein aP1 and the GDP-bound archaeal elongation factor aEF1alpha | Descriptor: | 50S ribosomal protein L12, Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE | Authors: | Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T. | Deposit date: | 2014-08-22 | Release date: | 2014-12-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha. Nucleic Acids Res., 42, 2014
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4MYU
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3WYA
| Crystal structure of GDP-bound EF1alpha from Pyrococcus horikoshii | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE | Authors: | Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T. | Deposit date: | 2014-08-22 | Release date: | 2014-12-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha. Nucleic Acids Res., 42, 2014
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6I3M
| eIF2B:eIF2 complex, phosphorylated on eIF2 alpha serine 52. | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Adomavicius, T, Roseman, A.M, Pavitt, G.D. | Deposit date: | 2018-11-06 | Release date: | 2019-05-22 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | The structural basis of translational control by eIF2 phosphorylation. Nat Commun, 10, 2019
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6ID0
| Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6I7T
| eIF2B:eIF2 complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Adomavicius, T, Guaita, M, Roseman, A.M, Pavitt, G.D. | Deposit date: | 2018-11-17 | Release date: | 2019-05-22 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.61 Å) | Cite: | The structural basis of translational control by eIF2 phosphorylation. Nat Commun, 10, 2019
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6JI2
| Crystal structure of archaeal ribosomal protein aP1, aPelota, and GTP-bound aEF1A complex | Descriptor: | Archaeal ribosomal stalk protein aP1, Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Maruyama, K, Imai, H, Kawamura, M, Ishino, S, Ishino, Y, Ito, K, Uchiumi, T. | Deposit date: | 2019-02-20 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations. Sci Rep, 9, 2019
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6QG1
| Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QDV
| Human post-catalytic P complex spliceosome | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. | Deposit date: | 2019-01-03 | Release date: | 2019-02-20 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science, 363, 2019
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6Q2D
| Crystal structure of Methanobrevibacter smithii Dph2 in complex with Methanobrevibacter smithii elongation factor 2 | Descriptor: | 2-(3-amino-3-carboxypropyl)histidine synthase, Elongation factor 2, IRON/SULFUR CLUSTER | Authors: | Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. | Deposit date: | 2019-08-07 | Release date: | 2019-10-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis. Biochemistry, 58, 2019
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6ID1
| Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6QG6
| Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.65 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG2
| Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG0
| Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG3
| Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6QG5
| Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C) | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ... | Authors: | Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (10.1 Å) | Cite: | Structural basis for the inhibition of translation through eIF2 alpha phosphorylation. Nat Commun, 10, 2019
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6GSM
| Structure of a partial yeast 48S preinitiation complex in open conformation. | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-06-14 | Release date: | 2019-07-31 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (5.15 Å) | Cite: | Large-scale movement of eIF3 domains during translation initiation modulate start codon selection. Nucleic Acids Res., 2021
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6GXM
| Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State II) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N. | Deposit date: | 2018-06-27 | Release date: | 2018-08-22 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1. Nat Commun, 9, 2018
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