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2XWJ	Crystal Structure of Complement C3b in Complex with Factor B Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ... Authors: Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. Deposit date: 2010-11-04 Release date: 2011-01-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (4 Å) Cite: Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
2XWB	Crystal Structure of Complement C3b in complex with Factors B and D Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ... Authors: Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. Deposit date: 2010-11-01 Release date: 2011-01-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.49 Å) Cite: Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
2ODP	Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Narayana, S.V.L, Krishnan, V. Deposit date: 2006-12-25 Release date: 2007-02-06 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The crystal structure of c2a, the catalytic fragment of classical pathway c3 and c5 convertase of human complement. J.Mol.Biol., 367, 2007
2OK5	Human Complement factor B Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement factor B, ... Authors: Milder, F.J, Gomes, L, Schouten, A, Janssen, B.J.C, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P. Deposit date: 2007-01-16 Release date: 2007-02-27 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Factor B structure provides insights into activation of the central protease of the complement system. Nat.Struct.Mol.Biol., 14, 2007
6CX1	Cryo-EM structure of Seneca Valley Virus-Anthrax Toxin Receptor 1 complex Descriptor: Anthrax toxin receptor 1, Capsid protein VP1, Capsid protein VP2, ... Authors: Jayawardena, N, Burga, L, Easingwood, R, Takizawa, Y, Wolf, M, Bostina, M. Deposit date: 2018-04-02 Release date: 2018-10-31 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2ODQ	Complement component C2a, the catalytic fragment of C3- and C5-convertase of human complement Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Narayana, S.V.L, Krishnan, V. Deposit date: 2006-12-25 Release date: 2007-02-06 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of c2a, the catalytic fragment of classical pathway c3 and c5 convertase of human complement. J.Mol.Biol., 367, 2007
6RUR	Structure of the SCIN stabilized C3bBb convertase bound to properdin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ... Authors: Pedersen, D.V, Gadeberg, T.A.F, Andersen, G.R. Deposit date: 2019-05-29 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (6 Å) Cite: Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
6RUV	Structure of the SCIN stabilized C3bBb convertase bound to Properdin and a the non-inhibitory nanobody hFPNb1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ... Authors: Pedersen, D.V, Andersen, G.R. Deposit date: 2019-05-29 Release date: 2019-08-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (6.15 Å) Cite: Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
4HQO	Crystal structure of Plasmodium vivax TRAP protein Descriptor: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ... Authors: Song, G, Koksal, A.C, Lu, C, Springer, T.A. Deposit date: 2012-10-25 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.194 Å) Cite: Shape change in the receptor for gliding motility in Plasmodium sporozoites. Proc.Natl.Acad.Sci.USA, 109, 2012
4HQL	Crystal structure of magnesium-loaded Plasmodium vivax TRAP protein Descriptor: CHLORIDE ION, MAGNESIUM ION, Sporozoite surface protein 2, ... Authors: Song, G, Koksal, A.C, Lu, C, Springer, T.A. Deposit date: 2012-10-25 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.241 Å) Cite: Shape change in the receptor for gliding motility in Plasmodium sporozoites. Proc.Natl.Acad.Sci.USA, 109, 2012
4HQN	Crystal structure of manganese-loaded Plasmodium vivax TRAP protein Descriptor: CHLORIDE ION, MANGANESE (II) ION, Sporozoite surface protein 2, ... Authors: Song, G, Koksal, A.C, Lu, C, Springer, T.A. Deposit date: 2012-10-25 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.196 Å) Cite: Shape change in the receptor for gliding motility in Plasmodium sporozoites. Proc.Natl.Acad.Sci.USA, 109, 2012
4HQF	Crystal structure of Plasmodium falciparum TRAP, I4 form Descriptor: CHLORIDE ION, Thrombospondin-related anonymous protein, TRAP Authors: Song, G, Koksal, A.C, Lu, C, Springer, T.A. Deposit date: 2012-10-25 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Shape change in the receptor for gliding motility in Plasmodium sporozoites. Proc.Natl.Acad.Sci.USA, 109, 2012
1RTK	Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid Descriptor: 4-carbamimidamidobenzoic acid, Complement factor B Bb fragment, IODIDE ION, ... Authors: Ponnuraj, K, Xu, Y, Macon, K, Moore, D, Volanakis, J.E, Narayana, S.V. Deposit date: 2003-12-10 Release date: 2004-12-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14, 2004
6NDB	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND COBALT Descriptor: AMMONIUM ION, CHLORIDE ION, COBALT (II) ION, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.2 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND COBALT To be published
6NDH	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND ZINC Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH ZINC BOUND To be published
6ND8	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND BARIUM Descriptor: AMMONIUM ION, BARIUM ION, CHLORIDE ION, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2018-12-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND BARIUM To be published
6NDD	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH MANGANESE BOUND Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2018-12-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.05 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH MANGANESE BOUND To be published
6NDF	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH STRONTIUM Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.05 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH STRONTIUM BOUND To be published
6NDG	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH YTTRIUM BOUND Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.15 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH YTTRIUM BOUND To be published
6NDA	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND CADMIUM Descriptor: AMMONIUM ION, CADMIUM ION, CHLORIDE ION, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2018-12-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.15 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND CADMIUM To be published
6NDC	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH CHROMIUM BOUND Descriptor: AMMONIUM ION, CHLORIDE ION, CHROMIUM ION, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.35 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH CHROMIUM BOUND To be published
6ND9	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH CALCIUM Descriptor: AMMONIUM ION, CALCIUM ION, CHLORIDE ION, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.9 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN AND CALCIUM To be published
6NDE	RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH PRASEDYMIUM Descriptor: AMMONIUM ION, CHLORIDE ION, Integrin alpha-2, ... Authors: Stetefeld, J, McDougall, M.D, Loewen, P.C. Deposit date: 2018-12-13 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.5 Å) Cite: RHODOCETIN IN COMPLEX WITH THE INTEGRIN ALPHA2-A DOMAIN WITH PRASEDYMIUM BOUND To be published
7JTQ	Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 31 Bases Descriptor: Complement factor B, DNA (32-MER) Authors: Xu, X, Geisbrecht, B.V. Deposit date: 2020-08-18 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B. J Immunol., 206, 2021
7JTN	Human Complement Factor B Inhibited by a Slow Off-Rate Modified Aptamer of 29 Bases Descriptor: Complement factor B, DNA (30-MER) Authors: Xu, X, Geisbrecht, B.V. Deposit date: 2020-08-18 Release date: 2020-12-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B. J Immunol., 206, 2021

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