1CL5
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1G4I
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![BU of 1g4i by Molmil](/molmil-images/mine/1g4i) | Crystal structure of the bovine pancreatic phospholipase A2 at 0.97A | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | Authors: | Steiner, R.A, Rozeboom, H.J, de Vries, A, Kalk, K.H, Murshudov, G.N, Wilson, K.S, Dijkstra, B.W. | Deposit date: | 2000-10-27 | Release date: | 2001-04-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | X-ray structure of bovine pancreatic phospholipase A2 at atomic resolution. Acta Crystallogr.,Sect.D, 57, 2001
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1G2X
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![BU of 1g2x by Molmil](/molmil-images/mine/1g2x) | Sequence induced trimerization of krait PLA2: crystal structure of the trimeric form of krait PLA2 | Descriptor: | PHOSPHOLIPASE A2 | Authors: | Singh, G, Gourinath, S, Sharma, S, Bhanumathi, S, Paramsivam, M, Singh, T.P. | Deposit date: | 2000-10-22 | Release date: | 2003-06-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Sequence-induced trimerization of phospholipase A2: structure of a trimeric isoform of PLA2 from common krait (Bungarus caeruleus) at 2.5 A resolution. Acta Crystallogr.,Sect.F, 61, 2005
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1FX9
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![BU of 1fx9 by Molmil](/molmil-images/mine/1fx9) | CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + MJ33 INHIBITOR + SULPHATE IONS) | Descriptor: | 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHOLIPASE A2, ... | Authors: | Pan, Y.H, Epstein, T.M, Jain, M.K, Bahnson, B.J. | Deposit date: | 2000-09-25 | Release date: | 2001-09-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Five coplanar anion binding sites on one face of phospholipase A2: relationship to interface binding. Biochemistry, 40, 2001
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1G0Z
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1FV0
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![BU of 1fv0 by Molmil](/molmil-images/mine/1fv0) | FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 9-HYDROXY ARISTOLOCHIC ACID, ACETATE ION, ... | Authors: | Chandra, V, Jasti, J, Kaur, P, Srinivasan, A, Betzel, C, Singh, T.P. | Deposit date: | 2000-09-18 | Release date: | 2002-08-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure Biochemistry, 41, 2002
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1GP7
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1J1A
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![BU of 1j1a by Molmil](/molmil-images/mine/1j1a) | PANCREATIC SECRETORY PHOSPHOLIPASE A2 (IIa) WITH ANTI-INFLAMMATORY ACTIVITY | Descriptor: | (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, Phospholipase A2 | Authors: | Hansford, K.A, Reid, R.C, Clark, C.I, Tyndall, J.D.A, Whitehouse, M.W, Guthrie, T, McGeary, R.P, Schafer, K, Martin, J.L, Fairlie, D.P. | Deposit date: | 2002-12-03 | Release date: | 2003-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity Chembiochem, 4, 2003
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1IJL
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![BU of 1ijl by Molmil](/molmil-images/mine/1ijl) | Crystal structure of acidic phospholipase A2 from deinagkistrodon acutus | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2, ZINC ION | Authors: | Gu, L, Zhang, H, Song, S, Zhou, Y, Lin, Z. | Deposit date: | 2001-04-27 | Release date: | 2001-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of an acidic phospholipase A2 from the venom of Deinagkistrodon acutus. Acta Crystallogr.,Sect.D, 58, 2002
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1IRB
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![BU of 1irb by Molmil](/molmil-images/mine/1irb) | CARBOXYLIC ESTER HYDROLASE | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Sundaralingam, M. | Deposit date: | 1997-08-13 | Release date: | 1997-12-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface. Biochemistry, 35, 1996
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1JLT
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![BU of 1jlt by Molmil](/molmil-images/mine/1jlt) | Vipoxin Complex | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHOLIPASE A2, ... | Authors: | Banumathi, S, Rajashankar, K.R, Notzel, C, Aleksiev, B, Singh, T.P, Genov, N, Betzel, C. | Deposit date: | 2001-07-16 | Release date: | 2001-10-31 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of the neurotoxic complex vipoxin at 1.4 A resolution. Acta Crystallogr.,Sect.D, 57, 2001
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1JQ8
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![BU of 1jq8 by Molmil](/molmil-images/mine/1jq8) | Design of specific inhibitors of phospholipase A2: Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.0 resolution | Descriptor: | ACETIC ACID, Peptide inhibitor, Phospholipase A2, ... | Authors: | Chandra, V, Jasti, J, Kaur, P, Dey, S, Betzel, C, Singh, T.P. | Deposit date: | 2001-08-04 | Release date: | 2002-11-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS). ACTA CRYSTALLOGR.,SECT.D, 58, 2002
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1HN4
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![BU of 1hn4 by Molmil](/molmil-images/mine/1hn4) | PROPHOSPHOLIPASE A2 DIMER COMPLEXED WITH MJ33, SULFATE, AND CALCIUM | Descriptor: | 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PROPHOSPHOLIPASE A2, ... | Authors: | Epstein, T.M, Pan, Y.H, Jain, M.K, Bahnson, B.J. | Deposit date: | 2000-12-06 | Release date: | 2001-12-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The basis for k(cat) impairment in prophospholipase A(2) from the anion-assisted dimer structure. Biochemistry, 40, 2001
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1KVW
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1KVY
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2PB8
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![BU of 2pb8 by Molmil](/molmil-images/mine/2pb8) | Crystal structure of the complex formed between phospholipase A2 and peptide Ala-Val-Tyr-Ser at 2.0 A resolution | Descriptor: | ACETATE ION, AVYS, Phospholipase A2 VRV-PL-VIIIa | Authors: | Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | Deposit date: | 2007-03-28 | Release date: | 2007-04-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the complex formed between phospholipase A2 and peptide Ala-Val-Tyr-Ser at 2.0 A resolution To be Published
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1JQ9
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![BU of 1jq9 by Molmil](/molmil-images/mine/1jq9) | Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Phe-Leu-Ser-Tyr-Lys at 1.8 resolution | Descriptor: | ACETIC ACID, Peptide inhibitor, Phospholipase A2 | Authors: | Chandra, V, Jasti, J, Kaur, P, Dey, S, Betzel, C, Singh, T.P. | Deposit date: | 2001-08-04 | Release date: | 2002-11-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution J.BIOL.CHEM., 277, 2002
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2OQD
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![BU of 2oqd by Molmil](/molmil-images/mine/2oqd) | Crystal Structure of BthTX-II | Descriptor: | Phospholipase A2 | Authors: | Correa, L.C, Marchi-Salvador, D.P, Cintra, A.C.O, Soares, A.M, Fontes, M.R.M. | Deposit date: | 2007-01-31 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal structure of a myotoxic Asp49-phospholipase A(2) with low catalytic activity: Insights into Ca(2+)-independent catalytic mechanism. Biochim.Biophys.Acta, 1784, 2008
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1KVX
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2OUB
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![BU of 2oub by Molmil](/molmil-images/mine/2oub) | Crystal structure of the complex formed between phospholipase A2 and atenolol at 2.75 A resolution | Descriptor: | 2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDE, Phospholipase A2 VRV-PL-VIIIa | Authors: | Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | Deposit date: | 2007-02-10 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of the complex formed between phospholipase A2 and atenolol at 2.75 A resolution To be Published
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1KVO
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![BU of 1kvo by Molmil](/molmil-images/mine/1kvo) | HUMAN PHOSPHOLIPASE A2 COMPLEXED WITH A HIGHLY POTENT SUBSTRATE ANOLOGUE | Descriptor: | 4-(S)-[(1-OXO-7-PHENYLHEPTYL)AMINO]-5-[4-(PHENYLMETHYL)PHENYLTHIO]PENTANOIC ACID, CALCIUM ION, HUMAN PHOSPHOLIPASE A2 | Authors: | Cha, S.-S, Abdel-Meguid, S.S, Oh, B.-H. | Deposit date: | 1996-07-29 | Release date: | 1997-07-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | High-resolution X-ray crystallography reveals precise binding interactions between human nonpancreatic secreted phospholipase A2 and a highly potent inhibitor (FPL67047XX). J.Med.Chem., 39, 1996
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1KPM
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![BU of 1kpm by Molmil](/molmil-images/mine/1kpm) | First Structural Evidence of a Specific Inhibition of Phospholipase A2 by Vitamin E and its Implications in Inflammation: Crystal Structure of the Complex Formed between Phospholipase A2 and Vitamin E at 1.8 A Resolution. | Descriptor: | ACETIC ACID, Phospholipase A2, VITAMIN E | Authors: | Chandra, V, Jasti, J, Kaur, P, Betzel, C, Srinivasan, A, Singh, T.P. | Deposit date: | 2002-01-01 | Release date: | 2002-07-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its
Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and
alpha-Tocopherol at 1.8 A Resolution J.Mol.Biol., 320, 2002
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2PMJ
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![BU of 2pmj by Molmil](/molmil-images/mine/2pmj) | Crystal structure of the complex formed between phospholipase A2 and 1, 2 benzopyrone at 2.4 A resolution | Descriptor: | ACETONITRILE, COUMARIN, Phospholipase A2 VRV-PL-VIIIa | Authors: | Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | Deposit date: | 2007-04-23 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the complex formed between phospholipase A2 and 1, 2 benzopyrone at 2.4 A resolution to be published
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1L8S
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2OK9
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![BU of 2ok9 by Molmil](/molmil-images/mine/2ok9) | PrTX-I-BPB | Descriptor: | ISOPROPYL ALCOHOL, Phospholipase A2 homolog 1, p-Bromophenacyl bromide | Authors: | Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R. | Deposit date: | 2007-01-16 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Crystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity. Biochim.Biophys.Acta, 1794, 2009
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