9BDL
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![BU of 9bdl by Molmil](/molmil-images/mine/9bdl) | 80S ribosome with angiogenin | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Loveland, A.B, Korostelev, A.A. | Deposit date: | 2024-04-12 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural mechanism of angiogenin activation by the ribosome. Nature, 630, 2024
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6Z4C
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![BU of 6z4c by Molmil](/molmil-images/mine/6z4c) | The structure of the N-terminal domain of RssB from E. coli | Descriptor: | Regulator of RpoS | Authors: | Zeth, K, Dimce, M, Terrence, D.M, Schuenemann, V, Dougan, D. | Deposit date: | 2020-05-25 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insight into the RssB-Mediated Recognition and Delivery of sigma s to the AAA+ Protease, ClpXP. Biomolecules, 10, 2020
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3E3M
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![BU of 3e3m by Molmil](/molmil-images/mine/3e3m) | Crystal structure of a LacI family transcriptional regulator from Silicibacter pomeroyi | Descriptor: | Transcriptional regulator, LacI family | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Iizuka, M, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-08-07 | Release date: | 2008-08-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a LacI family transcriptional regulator from Silicibacter pomeroyi To be Published
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3E7Q
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![BU of 3e7q by Molmil](/molmil-images/mine/3e7q) | The crystal structure of the putative transcriptional regulator from Pseudomonas aeruginosa PAO1 | Descriptor: | transcriptional regulator | Authors: | Zhang, R, Skarina, T, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-08-18 | Release date: | 2008-10-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structure of the putative transcriptional regulator from Pseudomonas aeruginosa PAO1 To be Published
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2ICU
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![BU of 2icu by Molmil](/molmil-images/mine/2icu) | Crystal Structure of Hypothetical Protein YedK From Escherichia coli | Descriptor: | Hypothetical protein yedK | Authors: | Chen, L, Liu, Z.J, Li, Y, Zhao, M, Rose, J, Ebihara, A, Yokoyama, S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-09-13 | Release date: | 2006-11-07 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Hypothetical Protein YedK From Escherichia coli To be Published
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9FBV
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![BU of 9fbv by Molmil](/molmil-images/mine/9fbv) | |
4V5B
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![BU of 4v5b by Molmil](/molmil-images/mine/4v5b) | Structure of PDF binding helix in complex with the ribosome. | Descriptor: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Bingel-Erlenmeyer, R, Kohler, R, Kramer, G, Sandikci, A, Antolic, S, Maier, T, Schaffitzel, C, Wiedmann, B, Bukau, B, Ban, N. | Deposit date: | 2007-11-22 | Release date: | 2014-07-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.74 Å) | Cite: | A Peptide Deformylase-Ribosome Complex Reveals Mechanism of Nascent Chain Processing. Nature, 452, 2008
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4V7K
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![BU of 4v7k by Molmil](/molmil-images/mine/4v7k) | Structure of RelE nuclease bound to the 70S ribosome (postcleavage state) | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | Deposit date: | 2009-11-02 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell(Cambridge,Mass.), 139, 2009
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6NZD
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![BU of 6nzd by Molmil](/molmil-images/mine/6nzd) | Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | Descriptor: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... | Authors: | Fromm, S.A, Young, L.N, Hurley, J.H. | Deposit date: | 2019-02-13 | Release date: | 2019-11-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science, 366, 2019
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4VUB
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![BU of 4vub by Molmil](/molmil-images/mine/4vub) | CCDB, A TOPOISOMERASE POISON FROM ESCHERICHIA COLI | Descriptor: | CCDB, CHLORIDE ION | Authors: | Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L. | Deposit date: | 1998-04-17 | Release date: | 1998-10-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of CcdB, a topoisomerase poison from E. coli. J.Mol.Biol., 285, 1999
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4D5F
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![BU of 4d5f by Molmil](/molmil-images/mine/4d5f) | |
5LYB
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![BU of 5lyb by Molmil](/molmil-images/mine/5lyb) | |
6D9X
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![BU of 6d9x by Molmil](/molmil-images/mine/6d9x) | Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design | Descriptor: | 2-phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole, SODIUM ION, WD repeat-containing protein 5 | Authors: | Phan, J, Fesik, S.W. | Deposit date: | 2018-04-30 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. J. Med. Chem., 61, 2018
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6DAI
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![BU of 6dai by Molmil](/molmil-images/mine/6dai) | Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design | Descriptor: | 6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-1-methylindoline, DIMETHYL SULFOXIDE, WD repeat-containing protein 5 | Authors: | Phan, J, Fesik, S.W. | Deposit date: | 2018-05-01 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. J. Med. Chem., 61, 2018
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4V4W
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![BU of 4v4w by Molmil](/molmil-images/mine/4v4w) | |
4V4V
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![BU of 4v4v by Molmil](/molmil-images/mine/4v4v) | |
3NBH
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![BU of 3nbh by Molmil](/molmil-images/mine/3nbh) | Crystal structure of human RMI1C-RMI2 complex | Descriptor: | RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | Authors: | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | Deposit date: | 2010-06-03 | Release date: | 2010-09-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex. Structure, 18, 2010
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4WLP
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![BU of 4wlp by Molmil](/molmil-images/mine/4wlp) | Crystal structure of UCH37-NFRKB Inhibited Deubiquitylating Complex | Descriptor: | Nuclear factor related to kappa-B-binding protein, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | Deposit date: | 2014-10-07 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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2IGI
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![BU of 2igi by Molmil](/molmil-images/mine/2igi) | Crystal Structure of E. coli Oligoribonuclease | Descriptor: | ACETIC ACID, CADMIUM ION, Oligoribonuclease, ... | Authors: | Zuo, Y, Malhotra, A. | Deposit date: | 2006-09-22 | Release date: | 2007-10-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli To be Published
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6YWX
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![BU of 6ywx by Molmil](/molmil-images/mine/6ywx) | The structure of the mitoribosome from Neurospora crassa with tRNA bound to the E-site | Descriptor: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-30 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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1JUN
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6YWE
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![BU of 6ywe by Molmil](/molmil-images/mine/6ywe) | The structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state | Descriptor: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-29 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWV
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![BU of 6ywv by Molmil](/molmil-images/mine/6ywv) | The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa | Descriptor: | 23 S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-30 | Release date: | 2020-11-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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7SYN
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![BU of 7syn by Molmil](/molmil-images/mine/7syn) | Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYJ
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![BU of 7syj by Molmil](/molmil-images/mine/7syj) | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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