PDB: 59042 resultsInfo pagesStatus searchChemie searchBIRD

---

7AE9	Crystal structure of mono-AMPylated HEPN(R46E) toxin in complex with MNT antitoxin Descriptor: 2',3'-DIDEOXYADENOSINE-5'-MONOPHOSPHATE, HEPN toxin, MNT ANTITOXIN Authors: Tamulaitiene, G, Sasnauskas, G, Songailiene, I, Juozapaitis, J, Siksnys, V. Deposit date: 2020-09-17 Release date: 2020-12-30 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation. Mol.Cell, 80, 2020
6QZR	14-3-3 sigma in complex with FOXO1 pT24 peptide Descriptor: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Forkhead box protein O1, ... Authors: Ottmann, C, Wolter, M, Lau, R.A. Deposit date: 2019-03-12 Release date: 2019-07-31 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. J.Biol.Chem., 294, 2019
8WNJ	Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Ile-AMP Descriptor: ACETATE ION, GLYCEROL, Isoleucine--tRNA ligase, ... Authors: Guo, Y, Li, S, Zhang, T. Deposit date: 2023-10-06 Release date: 2024-02-14 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase. Febs Lett., 598, 2024
3S22	AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with an inhibitor Descriptor: Beta-lactamase, CHLORIDE ION, [(2S,3R)-2-formyl-1-{[4-(methylamino)butyl]carbamoyl}pyrrolidin-3-yl]sulfamic acid Authors: Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. Deposit date: 2011-05-16 Release date: 2011-06-29 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
6NAB	Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with proline and adenosine monophophsphate (AMP) Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-12-05 Release date: 2019-01-30 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with proline and adenosine monophophsphate (AMP) TO BE PUBLISHED
1NJF	Nucleotide bound form of an isolated E. coli clamp loader gamma subunit Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
1NJG	Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit Descriptor: DNA polymerase III subunit gamma, SULFATE ION, ZINC ION Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
6XB6	Structure of Danaus plexippus poxin cGAMP nuclease Descriptor: Poxin Authors: Eaglesham, J.B, McCarty, K.L, Kranzusch, P.J. Deposit date: 2020-06-05 Release date: 2020-11-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9, 2020
6NFE	Crystal Structure of Ribose-phosphate Pyrophosphokinase from Legionella pneumophila with bound AMP, ADP, and Ribose-5-Phosphate Descriptor: 1,2-ETHANEDIOL, 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-12-19 Release date: 2019-01-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structure of Ribose-phosphate Pyrophosphokinase from Legionella pneumophila with bound AMP, ADP, and Ribose-5-Phosphate to be published
3I59	Crystal structure of MtbCRP in complex with N6-cAMP Descriptor: (2R)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, (2S)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, CHLORIDE ION, ... Authors: Reddy, M.C, Palaninathan, S.K, Bruning, J.B, Thurman, C, Smith, D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2009-07-03 Release date: 2009-09-08 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein. J.Biol.Chem., 284, 2009
3I62	Structure of Mss116p bound to ssRNA and ADP-Aluminum Fluoride Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ... Authors: Del Campo, M, Lambowitz, A.M. Deposit date: 2009-07-06 Release date: 2009-09-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA Mol.Cell, 35, 2009
3I61	Structure of Mss116p bound to ssRNA and ADP-Beryllium Fluoride Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ... Authors: Del Campo, M, Lambowitz, A.M. Deposit date: 2009-07-06 Release date: 2009-09-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA Mol.Cell, 35, 2009
4U2Q	Full-length AMPA subtype ionotropic glutamate receptor GluA2 in complex with partial agonist kainate Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 Authors: Duerr, K.L, Chen, L, Gouaux, E. Deposit date: 2014-07-17 Release date: 2014-08-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.5247 Å) Cite: Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
2QCS	A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that represents the inhibited state Descriptor: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... Authors: Kim, C, Cheng, C.Y, Saldanha, A.S, Taylor, S.S. Deposit date: 2007-06-19 Release date: 2007-11-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell(Cambridge,Mass.), 130, 2007
4BZP	Structure of the Mycobacterium tuberculosis APS kinase CysC in complex with ADP Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BIFUNCTIONAL ENZYME CYSN/CYSC Authors: Poyraz, O, Lohkamp, B, Schnell, R, Schneider, G. Deposit date: 2013-07-29 Release date: 2014-08-06 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Crystal Structures of the Kinase Domain of the Sulfate-Activating Complex in Mycobacterium Tuberculosis. Plos One, 10, 2015
4U4C	The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities Descriptor: 1,2-ETHANEDIOL, ATP-dependent RNA helicase DOB1, CHLORIDE ION, ... Authors: Falk, S, Weir, J.R, Hentschel, J, Reichelt, P, Bonneau, F, Conti, E. Deposit date: 2014-07-23 Release date: 2014-09-24 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities. Mol.Cell, 55, 2014
4O22	Binary complex of metal-free PKAc with SP20. Descriptor: Phosphorylated peptide pSP20., cAMP-dependent protein kinase catalytic subunit alpha. Authors: Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.S. Deposit date: 2013-12-16 Release date: 2014-05-28 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
4O21	Product complex of metal-free PKAc, ATP-gamma-S and SP20. Descriptor: ADENOSINE-5'-DIPHOSPHATE, Thio-phosphorylated peptide pSP20, cAMP-dependent protein kinase catalytic subunit alpha Authors: Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S. Deposit date: 2013-12-16 Release date: 2014-05-28 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
4LV0	AmpC beta-lactamase in complex with m-aminophenyl boronic acid Descriptor: Beta-lactamase, M-AMINOPHENYLBORONIC ACID, PHOSPHATE ION Authors: London, N, Eidam, O, Shoichet, B.K. Deposit date: 2013-07-25 Release date: 2014-07-30 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.652 Å) Cite: Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
9DJ8	RNA-nsp9 bound to the NiRAN domain of the E-RTC with an empty G-pocket Descriptor: ADENOSINE MONOPHOSPHATE, Non-structural protein 9, RNA-directed RNA polymerase, ... Authors: Small, G.I, Darst, S.A, Campbell, E.A. Deposit date: 2024-09-06 Release date: 2025-03-19 Method: ELECTRON MICROSCOPY (2.58 Å) Cite: Matters arising: There is no structure of the catalytic intermediate of GTP-mediated mRNA capping by the SARS-CoV-2 NiRAN domain, and thus the mechanism remains unknown To Be Published
3SG7	Crystal Structure of GCaMP3-KF(linker 1) Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
3SG5	Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2) Descriptor: CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
5XPU	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal Descriptor: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B Authors: Hara, K, Taharazako, S, Hashimoto, H. Deposit date: 2017-06-05 Release date: 2017-09-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.304 Å) Cite: Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
3SG2	Crystal Structure of GCaMP2-T116V,D381Y Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
3SG6	Crystal Structure of Dimeric GCaMP2-LIA(linker 1) Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012

<71727374757677787980818283848586>