8IFB
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![BU of 8ifb by Molmil](/molmil-images/mine/8ifb) | Dibekacin-bound E.coli 70S ribosome in the PURE system | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8Y0U
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![BU of 8y0u by Molmil](/molmil-images/mine/8y0u) | dormant ribosome with STM1 | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | dormant ribosome with STM1 To Be Published
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8IFC
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![BU of 8ifc by Molmil](/molmil-images/mine/8ifc) | Arbekacin-bound E.coli 70S ribosome in the PURE system | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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5LKS
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![BU of 5lks by Molmil](/molmil-images/mine/5lks) | Structure-function insights reveal the human ribosome as a cancer target for antibiotics | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | Authors: | Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. | Deposit date: | 2016-07-23 | Release date: | 2017-04-26 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7, 2016
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4V57
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![BU of 4v57 by Molmil](/molmil-images/mine/4v57) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. | Deposit date: | 2007-07-21 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A steric block in translation caused by the antibiotic spectinomycin. Acs Chem.Biol., 2, 2007
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8IFE
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![BU of 8ife by Molmil](/molmil-images/mine/8ife) | Arbekacin-added human 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8IFD
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![BU of 8ifd by Molmil](/molmil-images/mine/8ifd) | Dibekacin-added human 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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1W8C
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![BU of 1w8c by Molmil](/molmil-images/mine/1w8c) | |
4V52
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![BU of 4v52 by Molmil](/molmil-images/mine/4v52) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-15 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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7SEZ
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![BU of 7sez by Molmil](/molmil-images/mine/7sez) | Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with m7GDP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, DNA repair NTP-phosphohydrolase, SODIUM ION | Authors: | Peters, J.K, Tibble, R.W, Warminski, M, Jemielity, J, Gross, J.D. | Deposit date: | 2021-10-02 | Release date: | 2022-03-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.70001245 Å) | Cite: | Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis. Structure, 30, 2022
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7SF0
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![BU of 7sf0 by Molmil](/molmil-images/mine/7sf0) | Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with trinucleotide substrate | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, DNA repair NTP-phosphohydrolase, MAGNESIUM ION, ... | Authors: | Peters, J.K, Tibble, R.W, Warminski, M, Jemielity, J, Gross, J.D. | Deposit date: | 2021-10-02 | Release date: | 2022-03-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95000446 Å) | Cite: | Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis. Structure, 30, 2022
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4V54
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![BU of 4v54 by Molmil](/molmil-images/mine/4v54) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-16 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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4V5Y
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![BU of 4v5y by Molmil](/molmil-images/mine/4v5y) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-19 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (4.45 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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9BEZ
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![BU of 9bez by Molmil](/molmil-images/mine/9bez) | MID domain of human Argo2 bound to RNA | Descriptor: | Protein argonaute-2, [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate | Authors: | Harp, J.M, Egli, M. | Deposit date: | 2024-04-16 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
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3D2X
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![BU of 3d2x by Molmil](/molmil-images/mine/3d2x) | Structure of the thiamine pyrophosphate-specific riboswitch bound to oxythiamine pyrophosphate | Descriptor: | 3-[(4-hydroxy-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, MAGNESIUM ION, TPP-specific riboswitch | Authors: | Thore, S, Frick, C, Ban, N. | Deposit date: | 2008-05-09 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch J.Am.Chem.Soc., 130, 2008
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6FTI
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![BU of 6fti by Molmil](/molmil-images/mine/6fti) | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Braunger, K, Becker, T, Beckmann, R. | Deposit date: | 2018-02-22 | Release date: | 2018-03-21 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
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4V3O
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![BU of 4v3o by Molmil](/molmil-images/mine/4v3o) | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | Descriptor: | ACETATE ION, CALCIUM ION, YIII_M5_AII | Authors: | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | Deposit date: | 2014-10-20 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects Acta Crystallogr.,Sect.D, 72, 2016
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7ZCW
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![BU of 7zcw by Molmil](/molmil-images/mine/7zcw) | Cryo-EM structure of GMPCPP-microtubules in complex with VASH2-SVBP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Choi, S.R, Blum, T, Steinmetz, M.O. | Deposit date: | 2022-03-29 | Release date: | 2022-12-14 | Last modified: | 2023-06-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | VASH1-SVBP and VASH2-SVBP generate different detyrosination profiles on microtubules. J.Cell Biol., 222, 2023
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7CPU
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![BU of 7cpu by Molmil](/molmil-images/mine/7cpu) | Cryo-EM structure of 80S ribosome from mouse kidney | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | Authors: | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | Deposit date: | 2020-08-08 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
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8VDT
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![BU of 8vdt by Molmil](/molmil-images/mine/8vdt) | DNA Ligase 1 with nick DNA 3'rA:T | Descriptor: | DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*TP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*A)-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ... | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2023-12-17 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8WOQ
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![BU of 8woq by Molmil](/molmil-images/mine/8woq) | Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | Deposit date: | 2023-10-07 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1. Cell Discov, 10, 2024
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8VZL
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![BU of 8vzl by Molmil](/molmil-images/mine/8vzl) | DNA Ligase 1 captured with pre-step 3 ligation at the rG:C nicksite | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ... | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2024-02-11 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8VZM
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![BU of 8vzm by Molmil](/molmil-images/mine/8vzm) | DNA Ligase 1 captured with pre-step 3 ligation at the rA:T nicksite | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3'), ... | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2024-02-11 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8VDS
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![BU of 8vds by Molmil](/molmil-images/mine/8vds) | DNA Ligase 1 with nick DNA 3'rG:C | Descriptor: | DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*G)-D(P*GP*TP*CP*GP*GP*AP*C)-3') | Authors: | KanalElamparithi, B, Gulkis, M, Caglayan, M. | Deposit date: | 2023-12-17 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300, 2024
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8WOR
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![BU of 8wor by Molmil](/molmil-images/mine/8wor) | Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Liu, W, Tang, M, Wang, J, Zhang, X, Wu, S, Ru, H. | Deposit date: | 2023-10-07 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structural insights into cholesterol transport and hydrolase activity of a putative human RNA transport protein SIDT1. Cell Discov, 10, 2024
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