8VZL
DNA Ligase 1 captured with pre-step 3 ligation at the rG:C nicksite
Summary for 8VZL
Entry DOI | 10.2210/pdb8vzl/pdb |
Descriptor | DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*G)-3'), DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (6 entities in total) |
Functional Keywords | lig1, dna ligase 1, ligase, ligase-dna complex, ligase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 85680.05 |
Authors | KanalElamparithi, B.,Gulkis, M.,Caglayan, M. (deposition date: 2024-02-11, release date: 2024-05-22) |
Primary citation | Balu, K.E.,Gulkis, M.,Almohdar, D.,Caglayan, M. Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA. J.Biol.Chem., 300:107216-107216, 2024 Cited by PubMed: 38522520DOI: 10.1016/j.jbc.2024.107216 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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