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5GHD
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BU of 5ghd by Molmil
SOLUTION STRUCTURE OF LYS39 ACETYLATED HUMAN SUMO1
Descriptor: Small ubiquitin-related modifier 1
Authors:Naik, M.T, Naik, N, Shih, H, Huang, T.
Deposit date:2016-06-19
Release date:2017-06-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structures of Human Sumo
To Be Published
6PX7
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BU of 6px7 by Molmil
Dg12a in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
6PX8
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BU of 6px8 by Molmil
Dg3b in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
Descriptor: Venom polypeptide
Authors:Agwa, A.J, Schroeder, C.
Deposit date:2019-07-25
Release date:2020-01-22
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
6SGB
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BU of 6sgb by Molmil
mt-SSU assemblosome of Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
7SHQ
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BU of 7shq by Molmil
Structure of a functional construct of eukaryotic elongation factor 2 kinase in complex with calmodulin.
Descriptor: CALCIUM ION, Calmodulin-1, Eukaryotic elongation factor 2 kinase,Eukaryotic elongation factor 2 kinase, ...
Authors:Piserchio, A, Isiorho, E.A, Jeruzalmi, D, Dalby, K.N, Ghose, R.
Deposit date:2021-10-11
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase.
Sci Adv, 8, 2022
2K7M
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BU of 2k7m by Molmil
Structure of the Connexin40 Carboxyl terminal Domain
Descriptor: Gap junction alpha-5 protein
Authors:Bouvier, D, Spagnol, G, Kieken, F, Vitrac, H, Kellezi, A, Forge, V.
Deposit date:2008-08-14
Release date:2009-07-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains.
J.Biol.Chem., 284, 2009
2JP3
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BU of 2jp3 by Molmil
Solution Structure of the human FXYD4 (CHIF) protein in SDS micelles
Descriptor: FXYD domain-containing ion transport regulator 4
Authors:Franzin, C.M, Teriete, P, Marassi, F.M.
Deposit date:2007-04-18
Release date:2008-03-04
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Structural similarity of a membrane protein in micelles and membranes
J.Am.Chem.Soc., 129, 2007
7NH4
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BU of 7nh4 by Molmil
Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 3
Descriptor: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide
Authors:Landel, I, Mueller, M.P, Rauh, D.
Deposit date:2021-02-10
Release date:2021-09-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
7NH5
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BU of 7nh5 by Molmil
Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6
Descriptor: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide
Authors:Landel, I, Mueller, M.P, Rauh, D.
Deposit date:2021-02-10
Release date:2021-09-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
1NG8
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BU of 1ng8 by Molmil
G15-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)
Descriptor: GRAMICIDIN A
Authors:Sham, S.S, Townsley, L.E, Hinton, J.F.
Deposit date:2002-12-17
Release date:2002-12-31
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:The Structure, Cation Binding, Transport and Conductance of Gly15-Gramicidin a Incorporated Into Sds Micelles and Pc/Pg Vesicles
Biochemistry, 42, 2003
1NT6
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BU of 1nt6 by Molmil
F1-Gramicidin C In Sodium Dodecyl Sulfate Micelles (NMR)
Descriptor: GRAMICIDIN C
Authors:Townsley, L.E, Fletcher, T.G, Hinton, J.F.
Deposit date:2003-01-28
Release date:2003-02-11
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:The Structure, Cation Binding, Transport, and Conductance of Gly15-Gramicidin a Incorporated Into Sds Micelles and Pc/Pg Vesicles.
Biochemistry, 42, 2003
7T64
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BU of 7t64 by Molmil
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2021-12-13
Release date:2022-07-20
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T65
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BU of 7t65 by Molmil
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2021-12-13
Release date:2022-07-20
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
2JUL
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BU of 2jul by Molmil
NMR Structure of DREAM
Descriptor: CALCIUM ION, Calsenilin
Authors:Ames, J.
Deposit date:2007-08-30
Release date:2008-04-22
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structure of DREAM: Implications for Ca(2+)-dependent DNA binding and protein dimerization.
Biochemistry, 47, 2008
1NT5
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BU of 1nt5 by Molmil
F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)
Descriptor: GRAMICIDIN A
Authors:Townsley, L.E, Fletcher, T.G, Hinton, J.F.
Deposit date:2003-01-28
Release date:2003-02-11
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:The Structure, Cation Binding, Transport, and Conductance of Gly15-Gramicidin a Incorporated Into Sds Micelles and Pc/Pg Vesicles.
Biochemistry, 42, 2003
5A6R
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BU of 5a6r by Molmil
Crystal structure of the BTB domain of human KCTD17
Descriptor: BTB/POZ DOMAIN-CONTAINING PROTEIN KCTD17
Authors:Pinkas, D.M, Sorrell, F, Sanvitale, C.E, Goubin, S, Williams, E, Newman, J.A, Pearce, N.M, Neshich, I, Pike, A.C.W, MacKenzie, A, Quigley, A, Faust, B, Carpenter, E.P, Tallant, C, Kopec, J, Chalk, R, Krojer, T, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
Deposit date:2015-06-30
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Biochem. J., 474, 2017
7VUO
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BU of 7vuo by Molmil
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
Descriptor: CALCIUM ION, Calmodulin-1, Kv7.1
Authors:Chen, L.
Deposit date:2021-11-03
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.679 Å)
Cite:Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
To Be Published
2YGG
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BU of 2ygg by Molmil
Complex of CaMBR and CaM
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ...
Authors:Koester, S, Yildiz, O.
Deposit date:2011-04-15
Release date:2011-09-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.227 Å)
Cite:Structure of Human Na+/H+ Exchanger Nhe1 Regulatory Region in Complex with Cam and Ca2+
J.Biol.Chem., 286, 2011
1KIL
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BU of 1kil by Molmil
Three-dimensional structure of the complexin/SNARE complex
Descriptor: Complexin I SNARE-complex binding region, MAGNESIUM ION, SNAP-25 C-terminal SNARE motif, ...
Authors:Chen, X, Tomchick, D, Kovrigin, E, Arac, D, Machius, M, Sudhof, T.C, Rizo, J.
Deposit date:2001-12-03
Release date:2002-03-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of the complexin/SNARE complex.
Neuron, 33, 2002
7TDJ
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BU of 7tdj by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 1(Dataset-A)
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDG
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BU of 7tdg by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in inactivated conformation (Dataset-A)
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDH
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BU of 7tdh by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in open conformation
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDI
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BU of 7tdi by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 2 (Dataset-A)
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDK
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BU of 7tdk by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 3 (Dataset-A)
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
6QPB
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BU of 6qpb by Molmil
Cryo-EM structure of calcium-free mTMEM16F lipid scramblase in digitonin
Descriptor: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6
Authors:Alvadia, C, Lim, N.K, Clerico Mosina, V, Oostergetel, G.T, Dutzler, R, Paulino, C.
Deposit date:2019-02-13
Release date:2019-03-06
Last modified:2019-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F.
Elife, 8, 2019

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