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6EZ4
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BU of 6ez4 by Molmil
NMR structure of the C-terminal domain of the human RPAP3 protein
Descriptor: RNA polymerase II-associated protein 3
Authors:Fabre, P, Chagot, M.E, Bragantini, B, Manival, X, Quinternet, M.
Deposit date:2017-11-14
Release date:2018-04-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones.
Nat Commun, 9, 2018
6PKJ
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BU of 6pkj by Molmil
MicroED structure of proteinase K from an uncoated, single lamella at 2.17A resolution (#2)
Descriptor: Proteinase K
Authors:Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T.
Deposit date:2019-06-29
Release date:2019-09-04
Last modified:2019-12-18
Method:ELECTRON CRYSTALLOGRAPHY (2.176 Å)
Cite:Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
6PKO
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BU of 6pko by Molmil
MicroED structure of proteinase K from a platinum coated, unpolished, single lamella at 2.07A resolution (#12)
Descriptor: Proteinase K
Authors:Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T.
Deposit date:2019-06-29
Release date:2019-09-04
Last modified:2019-12-18
Method:ELECTRON CRYSTALLOGRAPHY (2.07 Å)
Cite:Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
6PKN
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BU of 6pkn by Molmil
MicroED structure of proteinase K from an unpolished, platinum-coated, single lamella at 2.08A resolution (#9)
Descriptor: Proteinase K
Authors:Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T.
Deposit date:2019-06-29
Release date:2019-09-04
Last modified:2019-12-18
Method:ELECTRON CRYSTALLOGRAPHY (2.08 Å)
Cite:Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
6PKR
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BU of 6pkr by Molmil
MicroED structure of proteinase K from a platinum-coated, polished, single lamella at 1.79A resolution (#13)
Descriptor: Proteinase K
Authors:Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T.
Deposit date:2019-06-29
Release date:2019-09-04
Last modified:2024-10-09
Method:ELECTRON CRYSTALLOGRAPHY (1.79 Å)
Cite:Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
6PKK
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BU of 6pkk by Molmil
MicroED structure of proteinase K from an uncoated, single lamella at 2.18A resolution (#5)
Descriptor: Proteinase K
Authors:Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T.
Deposit date:2019-06-29
Release date:2019-09-04
Last modified:2019-12-18
Method:ELECTRON CRYSTALLOGRAPHY (2.176 Å)
Cite:Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
6PKP
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BU of 6pkp by Molmil
MicroED structure of proteinase K from a platinum-coated, polished, single lamella at 1.91A resolution (#10)
Descriptor: Proteinase K
Authors:Martynowycz, M.W, Zhao, W, Hattne, J, Jensen, G.J, Gonen, T.
Deposit date:2019-06-29
Release date:2019-09-04
Last modified:2019-12-18
Method:ELECTRON CRYSTALLOGRAPHY (1.91 Å)
Cite:Qualitative Analyses of Polishing and Precoating FIB Milled Crystals for MicroED.
Structure, 27, 2019
7S7B
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BU of 7s7b by Molmil
Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1)
Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
7S7C
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BU of 7s7c by Molmil
Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2)
Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ...
Authors:Puno, M.R, Lima, C.D.
Deposit date:2021-09-15
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
Cell, 185, 2022
9B73
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BU of 9b73 by Molmil
Cryo-EM structure of the desensitised ATP-bound human P2X1 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Felix, M.B, Alisa, G, Hariprasad, V, Jesse, I.M, David, M.T.
Deposit date:2024-03-27
Release date:2024-10-09
Method:ELECTRON MICROSCOPY (1.96 Å)
Cite:Structural insights into the human P2X1 receptor and ligand interactions
Nat Commun, 15, 2024
8QPY
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BU of 8qpy by Molmil
Solution NMR structure of the peptidyl carrier domain TomAPCP from the Tomaymycin non-ribosomal peptide synthetase
Descriptor: Carrier protein TomAPCP
Authors:Karanth, M.N, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2023-10-03
Release date:2024-06-26
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain.
Sci Adv, 10, 2024
8SWF
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BU of 8swf by Molmil
Cryo-EM structure of NLRP3 open octamer
Descriptor: NACHT, LRR and PYD domains-containing protein 3
Authors:Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S.
Deposit date:2023-05-18
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
1ACC
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BU of 1acc by Molmil
ANTHRAX PROTECTIVE ANTIGEN
Descriptor: ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION
Authors:Petosa, C, Liddington, R.C.
Deposit date:1997-02-05
Release date:1998-02-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
1D6G
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BU of 1d6g by Molmil
MOLECULAR COMPLEX OF CHOLECYSTOKININ-8 AND N-TERMINUS OF THE CHOLECYSTOKININ A RECEPTOR BY NMR SPECTROSCOPY
Descriptor: cholecystokinin type a receptor, cholecystokinin-8
Authors:Pellegrini, M, Mierke, D.F.
Deposit date:1999-10-13
Release date:1999-11-17
Last modified:2021-07-07
Method:SOLUTION NMR
Cite:Molecular complex of cholecystokinin-8 and N-terminus of the cholecystokinin A receptor by NMR spectroscopy.
Biochemistry, 38, 1999
6DU8
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BU of 6du8 by Molmil
Human Polycsytin 2-l1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein
Authors:Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J.
Deposit date:2018-06-20
Release date:2018-07-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Cryo-EM structure of the polycystin 2-l1 ion channel.
Elife, 7, 2018
6D9O
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BU of 6d9o by Molmil
NMR solution structure of tamapin, mutant E25A
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Titaux Delgado, G.A, Mayorga Flores, M.
Deposit date:2018-04-30
Release date:2019-05-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells
Acs Med.Chem.Lett., 2020
7TYZ
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BU of 7tyz by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DARPin FSR22, ...
Authors:Kwon, Y.D, Gorman, J, Kwong, P.D.
Deposit date:2022-02-15
Release date:2022-12-07
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Nat.Chem.Biol., 19, 2023
6DLW
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BU of 6dlw by Molmil
Complement component polyC9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose
Authors:Dunstone, M.A, Spicer, B.A, Law, R.H.P.
Deposit date:2018-06-03
Release date:2018-09-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
6KI0
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BU of 6ki0 by Molmil
Crystal Structure of Human ASC-CARD
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Apoptosis-associated speck-like protein containing a CARD, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Xu, Z.H, Jin, T.C.
Deposit date:2019-07-16
Release date:2020-07-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome.
Cell Death Dis, 12, 2021
6DT6
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BU of 6dt6 by Molmil
Crystal Structure of the YopH PTP1B Chimera 3 PTPase bound to vanadate
Descriptor: Targeted effector protein, VANADATE ION
Authors:Morales, Y, Johnson, S.J, Hengge, A.C.
Deposit date:2018-06-15
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
Biochemistry, 57, 2018
6DB5
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BU of 6db5 by Molmil
Crystal structure of anti-HIV-1 V3 Fab TA6 in complex with a HIV-1 gp120 V3 peptide from NY5 strain
Descriptor: HIV-1 gp120 V3 peptide from NY5 strain, Human monoclonal anti-HIV-1 gp120 V3 antibody TA6 Fab heavy chain, Human monoclonal anti-HIV-1 gp120 V3 antibody TA6 Fab light chain
Authors:Chan, K.-W, Kong, X.-P.
Deposit date:2018-05-02
Release date:2018-07-11
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Structural Comparison of Human Anti-HIV-1 gp120 V3 Monoclonal Antibodies of the Same Gene Usage Induced by Vaccination and Chronic Infection.
J. Virol., 92, 2018
6DBV
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BU of 6dbv by Molmil
Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs
Descriptor: CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ...
Authors:Wu, H, Liao, M, Ru, H, Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.291 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6KNA
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BU of 6kna by Molmil
Viral Ubiquitin from Autographa californica Nucleo Polyhedrosis Virus
Descriptor: Viral ubiquitin
Authors:Negi, H, Reddy, P.P, Das, R.
Deposit date:2019-08-05
Release date:2020-06-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A novel polyubiquitin chain linkage formed by viral Ubiquitin is resistant to host deubiquitinating enzymes.
Biochem.J., 477, 2020
6K8Q
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BU of 6k8q by Molmil
Solution structure of the intermembrane space domain of the mitochondrial import protein Tim21 from S. cerevisiae
Descriptor: Mitochondrial import inner membrane translocase subunit TIM21
Authors:Bala, S, Shinya, S, Srivastava, A, Shimada, A, Kobayashi, N, Kojima, C, Tama, F, Miyashita, O, Kohda, D.
Deposit date:2019-06-13
Release date:2019-09-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Crystal contact-free conformation of an intrinsically flexible loop in protein crystal: Tim21 as the case study.
Biochim Biophys Acta Gen Subj, 1864, 2020
6K2K
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BU of 6k2k by Molmil
Solution structure of MUL1-RING domain
Descriptor: Mitochondrial ubiquitin ligase activator of NFKB 1, ZINC ION
Authors:Lee, M.S, Lee, M.K, Ryu, K.S, Chi, S.W.
Deposit date:2019-05-14
Release date:2019-07-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of MUL1-RING domain and its interaction with p53 transactivation domain.
Biochem.Biophys.Res.Commun., 516, 2019

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