PDB: 243911 resultsInfo pagesStatus searchChemie searchBIRD

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4FSM	Crystal Structure of the CHK1 Descriptor: 4-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenol, GLYCEROL, ISOPROPYL ALCOHOL, ... Authors: Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. Deposit date: 2012-06-27 Release date: 2012-08-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of the CHK1 To be Published
4FYV	Aspartate Transcarbamoylase Complexed with dCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ... Authors: Cockrell, G.M, Kantrowitz, E.R. Deposit date: 2012-07-05 Release date: 2012-10-10 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.0976 Å) Cite: Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
4FZI	Crystal structure of prostaglandin F synthase from Trypanosoma cruzi Descriptor: GLUTAMIC ACID, Prostaglandin F synthase, SULFATE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-07-06 Release date: 2012-07-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71, 2015
4FSV	Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution Descriptor: Heat shock-related 70 kDa protein 2 Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-06-27 Release date: 2012-07-18 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A resolution To be published
4FT9	Crystal Structure of the CHK1 Descriptor: 1-(5-cyanopyrazin-2-yl)-3-isoquinolin-3-ylurea, SULFATE ION, Serine/threonine-protein kinase Chk1 Authors: Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. Deposit date: 2012-06-27 Release date: 2012-08-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of the CHK1 To be Published
4FTK	Crystal Structure of the CHK1 Descriptor: 3-(4'-hydroxybiphenyl-4-yl)-2,4-dihydroindeno[1,2-c]pyrazol-6-ol, ISOPROPYL ALCOHOL, SULFATE ION, ... Authors: Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. Deposit date: 2012-06-27 Release date: 2012-08-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of the CHK1 To be Published
4FTV	The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide Descriptor: A6 alpha chain, A6 beta chain, Beta-2-microglobulin, ... Authors: Borbulevych, O.Y, Baker, B.M. Deposit date: 2012-06-28 Release date: 2013-07-03 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity To be Published
4FUU	Crystal structure of a leucine aminopeptidase precursor (BT_2548) from Bacteroides thetaiotaomicron VPI-5482 at 1.30 A resolution Descriptor: 1,2-ETHANEDIOL, Leucine aminopeptidase, PHOSPHATE ION, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2012-06-28 Release date: 2012-10-31 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal structure of a leucine aminopeptidase precursor (BT_2548) from Bacteroides thetaiotaomicron VPI-5482 at 1.30 A resolution To be published
4G0S	Crystal Structure of Epiphyas postvittana Takeout 1 expressed in Sf9 cells Descriptor: MYRISTIC ACID, Takeout-like protein 1 Authors: Hamiaux, C, Baker, E.N, Newcomb, R.D. Deposit date: 2012-07-10 Release date: 2013-05-01 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.191 Å) Cite: Ligand promiscuity within the internal cavity of Epiphyas postvittana Takeout 1 protein. J.Struct.Biol., 182, 2013
4FV8	Crystal Structure of the ERK2 complexed with E63 Descriptor: 1,2-ETHANEDIOL, 6-({4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3H-indazol-3-one, Mitogen-activated protein kinase 1, ... Authors: Kang, Y.N, Stuckey, J.A, Xie, X. Deposit date: 2012-06-29 Release date: 2012-08-29 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of the ERK2 complexed with E63 TO BE PUBLISHED
4FVR	Crystal structure of the Jak2 pseudokinase domain mutant V617F (Mg-ATP-bound form) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tyrosine-protein kinase JAK2 Authors: Bandaranayake, R.M, Hubbard, S.R. Deposit date: 2012-06-29 Release date: 2012-07-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F. Nat.Struct.Mol.Biol., 19, 2012
4G2T	Crystal Structure of Streptomyces sp. SF2575 glycosyltransferase SsfS6, complexed with thymidine diphosphate Descriptor: SsfS6, THYMIDINE-5'-DIPHOSPHATE Authors: Wang, F, Zhou, M, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) Deposit date: 2012-07-12 Release date: 2012-07-25 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.405 Å) Cite: Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins, 81, 2013
4G8E	Crystal Structure of clone18 TCR Descriptor: alpha chain clone 18 TCR, beta chain clone 18 TCR Authors: Gras, S, Bhati, M, Rossjohn, J. Deposit date: 2012-07-23 Release date: 2013-05-08 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat.Immunol., 14, 2013
4G96	Crystal structure of calcium2+-free wild-type CD23 lectin domain Descriptor: 1,2-ETHANEDIOL, Low affinity immunoglobulin epsilon Fc receptor, SULFATE ION Authors: Yuan, D, Sutton, B.J, Dhaliwal, B. Deposit date: 2012-07-23 Release date: 2013-06-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J.Biol.Chem., 288, 2013
4G2S	Crystal structure of a Salmonella type III secretion system protein Descriptor: CALCIUM ION, Protein prgH Authors: Worrall, L.J, Vuckovic, M, Strynadka, N.C.J. Deposit date: 2012-07-12 Release date: 2013-05-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.858 Å) Cite: A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. Plos Pathog., 9, 2013
4GAB	Human AKR1B10 mutant V301L complexed with NADP+ and fidarestat Descriptor: (2S,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE, Aldo-keto reductase family 1 member B10, CHLORIDE ION, ... Authors: Cousido-Siah, A, Ruiz Figueras, F.X, Mitschler, A, Podjarny, A. Deposit date: 2012-07-25 Release date: 2013-03-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5971 Å) Cite: X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity. Chem.Biol.Interact, 202, 2013
4GAK	Crystal structure of acyl-ACP thioesterase from Spirosoma linguale Descriptor: Acyl-ACP thioesterase, CHLORIDE ION, GLYCEROL Authors: Chang, C, Wu, R, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2012-07-25 Release date: 2012-09-19 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of acyl-ACP thioesterase from Spirosoma linguale To be Published
4GBM	Sulfotransferase Domain from the Curacin Biosynthetic Pathway Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, CHLORIDE ION, CurM Sulfotransferase, ... Authors: McCarthy, J.G, Smith, J.L. Deposit date: 2012-07-27 Release date: 2012-10-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. Acs Chem.Biol., 7, 2012
4G6R	Minimal Hairpin Ribozyme in the Transition State with G8I Variation Descriptor: Loop A Ribozyme strand, Loop A Substrate strand, Loop B Ribozyme Strand, ... Authors: Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. Deposit date: 2012-07-19 Release date: 2012-08-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.832 Å) Cite: A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis. J.Am.Chem.Soc., 134, 2012
4G85	Crystal structure of human HisRS Descriptor: Histidine-tRNA ligase, cytoplasmic Authors: Wei, Z, Wu, J, Zhou, J.J, Yang, X.-L, Zhang, M, Schimmel, P. Deposit date: 2012-07-21 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing. Structure, 20, 2012
4G9F	Crystal Structure of C12C TCR-HLAB2705-KK10-L6M Descriptor: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen, ... Authors: Gras, S, Wilmann, P.G, Rossjohn, J. Deposit date: 2012-07-23 Release date: 2013-03-20 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
4GG5	Crystal structure of CMET in complex with novel inhibitor Descriptor: 3-(4-methylpiperazin-1-yl)-N-(3-nitrobenzyl)-7-(trifluoromethyl)quinolin-5-amine, Hepatocyte growth factor receptor Authors: Liu, Q.F, Chen, T.T, Xu, Y.C. Deposit date: 2012-08-05 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.423 Å) Cite: Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
4GA1	Structure of the N-terminal domain of Nup358 Descriptor: E3 SUMO-PROTEIN LIGASE RANBP2 Authors: Hoelz, A, Kassube, S.A, Lin, D.H, Stuwe, T. Deposit date: 2012-07-24 Release date: 2012-09-26 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Crystal structure of the N-terminal domain of Nup358/RanBP2. J.Mol.Biol., 423, 2012
4GB9	Potent and Highly Selective Benzimidazole Inhibitors of PI3K-delta Descriptor: 2-[1-({2-[2-(dimethylamino)-1H-benzimidazol-1-yl]-9-methyl-6-(morpholin-4-yl)-9H-purin-8-yl}methyl)piperidin-4-yl]propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Authors: Murray, J.M. Deposit date: 2012-07-26 Release date: 2012-08-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.438 Å) Cite: Potent and highly selective benzimidazole inhibitors of PI3-kinase delta. J.Med.Chem., 55, 2012
4FVD	Crystal structure of EV71 2A proteinase C110A mutant in complex with substrate Descriptor: 10-mer peptide from 2A proteinase, 2A proteinase, ZINC ION Authors: Cai, Q, Muhammad, Y, Liu, W, Gao, Z, Peng, X, Cai, Y, Wu, C, Zheng, Q, Li, J, Lin, T. Deposit date: 2012-06-29 Release date: 2013-06-19 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Conformational Plasticity of 2A Proteinase from Enterovirus 71 J.Virol., 87, 2013

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