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5J4P	DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTTGG) in sodium Descriptor: DNA (5'-D(*GP*GP*TP*TP*TP*GP*GP*TP*TP*TP*TP*GP*GP*TP*TP*TP*GP*G)-3') Authors: Dvorkin, S.A, Webba da Silva, M. Deposit date: 2016-04-01 Release date: 2017-06-14 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Encoding canonical DNA quadruplex structure. Sci Adv, 4, 2018
5J4W	DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTGG) in sodium Descriptor: DNA (5'-D(*GP*GP*TP*TP*TP*GP*GP*TP*TP*TP*TP*GP*GP*TP*TP*GP*G)-3') Authors: Dvorkin, S.A, Webba da Silva, M. Deposit date: 2016-04-01 Release date: 2017-04-12 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Encoding canonical DNA quadruplex structure. Sci Adv, 4, 2018
1NZM	NMR structure of the parallel-stranded DNA quadruplex d(TTAGGGT)4 complexed with the telomerase inhibitor RHPS4 Descriptor: 3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM, 5'-D(*TP*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION Authors: Gavathiotis, E, Heald, R.A, Stevens, M.F.G, Searle, M.S. Deposit date: 2003-02-18 Release date: 2003-11-04 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Drug Recognition and Stabilisation of the Parallel-stranded DNA Quadruplex d(TTAGGGT)4 Containing the Human Telomeric Repeat J.Mol.Biol., 334, 2003
5YEY	The structure of a chair-type G-quadruplex of the human telomeric variant in K+ solution Descriptor: DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*TP*GP*GP*G)-3') Authors: Liu, C, Zhou, B, Kuryavyi, V.V, Zhu, G. Deposit date: 2017-09-20 Release date: 2018-09-26 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K+solution. Chem Sci, 10, 2019
5DWW	Structural Insights into the Quadruplex-Duplex 3' Interface formed from a Telomeric Repeat - TTLOOP Descriptor: DNA (25-MER), DNA (5'-D(*TP*AP*AP*CP*GP*CP*TP*A)-3'), POTASSIUM ION Authors: Russo Krauss, I, Parkinson, G.N. Deposit date: 2015-09-23 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Structural Insights into the Quadruplex-Duplex 3' Interface Formed from a Telomeric Repeat: A Potential Molecular Target. J.Am.Chem.Soc., 138, 2016
5MVB	Solution structure of a human G-Quadruplex hybrid-2 form in complex with a Gold-ligand. Descriptor: DNA (26-MER), POTASSIUM ION, bis(m2-Oxo)-bis(2-methyl-2,2'-bipyridine)-di-gold(iii) Authors: Wirmer-Bartoschek, J, Jonker, H.R.A, Bendel, L.E, Gruen, T, Bazzicalupi, C, Messori, L, Gratteri, P, Schwalbe, H. Deposit date: 2017-01-16 Release date: 2017-05-31 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Solution NMR Structure of a Ligand/Hybrid-2-G-Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding. Angew. Chem. Int. Ed. Engl., 56, 2017
5ZEV	Solution structure of G-quadruplex formed in vegfr-2 proximal promoter sequence Descriptor: DNA (5'-D(*GP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*TP*GP*AP*GP*GP*TP*GP*CP*GP*GP*GP*GP*T)-3') Authors: Liu, Y, Lan, W.X. Deposit date: 2018-02-28 Release date: 2018-04-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: A putative G-quadruplex structure in the proximal promoter ofVEGFR-2has implications for drug design to inhibit tumor angiogenesis. J. Biol. Chem., 293, 2018
6SX6	Guanine-rich oligonucleotide with 5'-GC end form G-quadruplex with A(GGGG)A hexad, GCGC- and G-quartets and two symmetric GG and AA base pairs Descriptor: GCn Authors: Pavc, D, Wang, B, Spindler, L, Drevensek-Olenik, I, Plavec, J, Sket, P. Deposit date: 2019-09-25 Release date: 2020-07-22 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: GC ends control topology of DNA G-quadruplexes and their cation-dependent assembly. Nucleic Acids Res., 48, 2020
1MYQ	An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction Descriptor: 5'-D(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3' Authors: Matsugami, A, Ouhashi, K, Kanagawa, M, Liu, H, Kanagawa, S, Uesugi, S, Katahira, M. Deposit date: 2002-10-04 Release date: 2002-10-23 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: An intramolecular quadruplex of (GGA)(4) triplet repeat DNA with a G:G:G:G tetrad and a G(:A):G(:A):G(:A):G heptad, and its dimeric interaction. J.Mol.Biol., 313, 2001
1K8P	Structure of the Human G-quadruplex reveals a novel topology Descriptor: 5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION, SODIUM ION Authors: Parkinson, G.N, Lee, M.P.H, Neidle, S. Deposit date: 2001-10-25 Release date: 2002-05-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of parallel quadruplexes from human telomeric DNA. Nature, 417, 2002
6A85	Crystal structure of a novel DNA quadruplex Descriptor: AMMONIUM ION, DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*GP*GP*GP*TP*GP*CP*GP*TP*T)-3'), LEAD (II) ION, ... Authors: Liu, H.H, Gan, J.H. Deposit date: 2018-07-06 Release date: 2019-03-06 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.45 Å) Cite: High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads. Nucleic Acids Res., 46, 2018
1VYA	Identification and characterization of the first plant G-quadruplex binding protein encoded by the Zea mays L. nucleoside diphosphate1 gene, ZmNDPK1 Descriptor: Nucleoside diphosphate kinase Authors: Kopylov, M, Stroupe, M.E. Deposit date: 2014-08-14 Release date: 2015-04-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.05 Å) Cite: The Maize (Zea mays L.) Nucleoside Diphosphate Kinase1 (ZmNDPK1) Gene Encodes a Human NM23-H2 Homologue That Binds and Stabilizes G-Quadruplex DNA. Biochemistry, 54, 2015
8C7B	Slow cation movements within tetramolecular G-quadruplex: vacant cation binding sites in addition to all syn G-quartet Descriptor: DNA (5'-D(*GP*GP*GP*GP*CP*C)-3') Authors: Wang, B, Zalar, M, Plavec, J, Sket, P. Deposit date: 2023-01-14 Release date: 2023-11-22 Method: SOLUTION NMR Cite: Insight into Tetramolecular DNA G-Quadruplexes Associated with ALS and FTLD: Cation Interactions and Formation of Higher-Ordered Structure. Int J Mol Sci, 24, 2023
8C7A	Slow cation movements within tetramolecular G-quadruplex: vacant cation binding sites in addition to all syn G-quartet Descriptor: DNA (5'-D(*GP*GP*GP*GP*CP*C)-3') Authors: Wang, B, Zalar, M, Plavec, J, Sket, P. Deposit date: 2023-01-14 Release date: 2023-11-22 Method: SOLUTION NMR Cite: Insight into Tetramolecular DNA G-Quadruplexes Associated with ALS and FTLD: Cation Interactions and Formation of Higher-Ordered Structure. Int J Mol Sci, 24, 2023
6ZL2	Structure of a parallel c-Myc modified with 3' duplex stem-loop overhang Descriptor: DNA (36-MER) Authors: Vianney, Y.M, Weisz, K. Deposit date: 2020-06-30 Release date: 2020-10-07 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands. Chemistry, 26, 2020
6ZL9	Structure of a parallel c-Myc modified with 5' duplex stem-loop overhang Descriptor: DNA (35-MER) Authors: Vianney, Y.M, Weisz, K. Deposit date: 2020-06-30 Release date: 2020-10-07 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands. Chemistry, 26, 2020
6ZTE	Structure of a parallel c-myc modified with 5' duplex stem-loop and 3' diagonal snap-back loop Descriptor: DNA (36-MER) Authors: Vianney, Y.M, Weisz, K. Deposit date: 2020-07-20 Release date: 2020-10-07 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands. Chemistry, 26, 2020
6ZX6	Antiparallel basket-type G-quadruplex DNA structure formed in human Bcl-2 promoter containing 8-oxoG Descriptor: bcl2ex-oxoG19 Authors: Bielskute, S, Plavec, J, Podbevsek, P. Deposit date: 2020-07-29 Release date: 2021-03-10 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter. Nucleic Acids Res., 49, 2021
6ZX7	Antiparallel basket-type G-quadruplex DNA structure formed in human Bcl-2 promoter Descriptor: bcl2ex Authors: Bielskute, S, Plavec, J, Podbevsek, P. Deposit date: 2020-07-29 Release date: 2021-03-10 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter. Nucleic Acids Res., 49, 2021
8PSE	(3+1) hybrid G-quadruplex from a G-rich sequence with five G-runs Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*(BG)P*GP*TP*AP*CP*GP*GP*GP*T)-3') Authors: Jana, J, Vianney, Y.M, Schroder, N, Weisz, K. Deposit date: 2023-07-13 Release date: 2023-09-27 Last modified: 2023-10-18 Method: SOLUTION NMR Cite: Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect. J.Am.Chem.Soc., 145, 2023
8PSC	Three-layered basket-type G-quadruplex from a G-rich sequence with five G-runs Descriptor: DNA (5'-D(*AP*GP*(BG)P*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3') Authors: Vianney, Y.M, Schroeder, N, Jana, J, Weisz, K. Deposit date: 2023-07-13 Release date: 2023-09-27 Last modified: 2023-10-18 Method: SOLUTION NMR Cite: Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect. J.Am.Chem.Soc., 145, 2023
8PSB	Three-layered parallel G-quadruplex with snapback loop from a G-rich sequence with five G-runs Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*AP*CP*GP*GP*GP*T)-3') Authors: Vianney, Y.M, Schroeder, N, Jana, J, Chojetzki, G, Weisz, K. Deposit date: 2023-07-13 Release date: 2023-09-27 Last modified: 2023-10-25 Method: SOLUTION NMR Cite: Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect. J.Am.Chem.Soc., 145, 2023
6GH0	Two-quartet kit* G-quadruplex is formed via double-stranded pre-folded structure Descriptor: DNA (5'-D(*GP*GP*CP*GP*AP*GP*GP*AP*GP*GP*GP*GP*CP*GP*TP*GP*GP*CP*CP*GP*GP*C)-3') Authors: Kotar, A, Rigo, R, Sissi, C, Plavec, J. Deposit date: 2018-05-04 Release date: 2019-01-09 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Two-quartet kit* G-quadruplex is formed via double-stranded pre-folded structure. Nucleic Acids Res., 47, 2019
1MY9	Solution structure of a K+ cation stabilized dimeric RNA quadruplex containing two G:G(:A):G:G(:A) hexads, G:G:G:G tetrads and UUUU loops Descriptor: 5'-R(*GP*GP*AP*GP*GP*UP*UP*UP*UP*GP*GP*AP*GP*G)-3' Authors: Liu, H, Matsugami, A, Katahira, M, Uesugi, S. Deposit date: 2002-10-04 Release date: 2003-10-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: A Dimeric RNA Quadruplex Architecture Comprised of Two G:G(:A):G:G(:A) Hexads, G:G:G:G Tetrads and UUUU Loops J.Mol.Biol., 322, 2002
1L1H	Crystal Structure of the Quadruplex DNA-Drug Complex Descriptor: 3-PYRROLIDIN-1-YL-N-[6-(3-PYRROLIDIN-1-YL-PROPIONYLAMINO)-ACRIDIN-3-YL]-PROPIONAMIDE, 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION Authors: Haider, S.M, Parkinson, G.N, Neidle, S. Deposit date: 2002-02-16 Release date: 2003-02-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure of a G-quadruplex-Ligand Complex J.Mol.Biol., 326, 2003

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